MCPA SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： MCPA
- CAS： 3653-48-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Acute toxicity - Category 4, Inhalation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: MCPA
- Common names and synonyms: MCPA
- CAS number: 3653-48-3
- EC number: 222-895-9
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
Treatment is symptomatic and supportive. Oils should not be used as either cathartics or dermal cleansing agents, as they increase absorption. Gastric lavage and use of activated charcoal and sodium sulfate are indicated for ingestion. If dermal exposure occurred, contaminated clothes should be removed, and the skin should be thoroughly cleansed with soap and water. Management of seizures in both children and adults is with Valium or phenobarbital. Respiratory depression and even respiratory arrest especially with concomitant use of Valium and phenobarbital in children, may occur. These drugs preferably should be used only in critical care areas where emergency endotracheal intubation can be performed. ... Epinephrine can not be utilized in patients with organochlorine poisoning, as the organochlorines induce myocardial irritability and ventricular arrhythmias may occur. However, dopamine may be necessary in the event of hypotension unresponsive to fluid administration, and epinephrin may be necessary in the event of cardiopulmonary arrest. ... In a critically ill patient with unknown insecticide exposure, ... Atropine must be used with caution, as it can cause ventricular irritability, especially when a myocardial irritant such as an organochlorine is present. ... Hematologic, hepatic (especially with endrin, which is markedly hepatotoxic), and renal studies as well as cardiopulmonary monitoring should be carried out in acute intoxication from lindane or other organochlorines for at least 48 to 72 hr. Long term hematologic follow-up is necessary for the patient with lindane intoxication. As the carrier for these agents may be xylene or a petroleum distillate, management also must include observation and treatment for these entities. Organochlorine pesticides
SECTION 5: Firefighting measures
Suitable extinguishing media
Use dry chemical, carbon dioxide or alcohol-resistant foam.
Specific hazards arising from the chemical
no data available
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep in well-ventilated area.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Methoxone sodium salt is a colorless plates. Corrosive. Used as an herbicide.
-
Colour：
White to light brown solid flakes, crystal powder or liquid.
-
Odour：
no data available
-
Melting point/freezing point：
118-119°C
-
Boiling point or initial boiling point and boiling range：
327°C at 760mmHg
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
151.6°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
INSOL IN CARBON DISULFIDE; SOLUBILITY (G/100 ML): ETHER 77, ETHANOL 153, N-HEPTANE 0.5, TOLUENE 6.2, XYLENE 4.9
-
Partition coefficient n-octanol/water：
log Kow = 3.25
-
Vapour pressure：
5.90X10-6 mm Hg
-
Density and/or relative density：
1.56 @ 25 DEG C/15.5 DEG C
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Very soluble in water.
Chemical stability
NONVOLATILE
Possibility of hazardous reactions
NonflammableMETHOXONE SODIUM SALT is a salt of a chlorinated benzoic acid.
Conditions to avoid
no data available
Incompatible materials
Reacts with alkalis to form salts
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /hydrogen chloride and nitrogen oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat male oral 700 mg/kg
- Inhalation: no data available
- Dermal: LD50 Rat percutaneous >1000 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Not Likely to be Carcinogenic to Humans
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Salmo gairdneri (Rainbow trout) 232 mg/l/96 hr /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Microbial degradation of MCPA in soil was followed by measuring radiolabeled 14-CO2 evolution(1); in non-acclimated soil, CO2 evolution reached 40-50% after 78 days of incubation(1). At an initial MCPA concn of 5 mg/kg, CO2 evolution increased markedly after a 2-3 week lag period indicating that microbial adaptation will increase the degradation rate(1); optimum degradation occurred in soil with a moisture content of 0.6 to 1.2 field capacity(1) while degradation in dry soil was negligible(1). The importance of acclimation was demonstrated in soil degradation tests in which degradation in unacclimated soil required 46-82 days, but only 5-14.5 days were required for a subsequent degradation in the same soil(2); sterilization tests (via sodium azide) indicated that all soil degradation was microbial in nature(2). The results of laboratory studies indicated that 14C-labeled MCPA would degrade faster in soils that had received previous applications than in untreated soils(3). Microbial degradation in soil is probably due to hydroxylation with cleavage of the ether linkage (4). The dechlorination of MCPA was indicated as an acid-yielding reaction and was observed to reduce the pH in a mixed culture medium; no degradation occurred in cultures above pH 8.5 and degradation was slower at higher concns(5). In samples of sandy clay soil (pH 5.2, organic matter 6.3%) at field capacity moisture content (18.2%) and incubated at 23 deg C for up to 32 weeks, MCPA, at initial concns of 10, 100, 200 and 500 ppm, degraded more rapidly at the lower concns(6). Respective losses of 40%, 60% and 90% were observed at 2, 8 and 32 weeks; the degradates were identified as 4-chloro-o-cresol, 5-chloro-3-methylcatechol, and 2,6-dimethoxyphenol(6).
Bioaccumulative potential
A BCF of 1 was determined for trout at MCPA aqueous concns of 10-100 mg/l and using an exposure period of 10-28 day(1). In a model aquatic ecosystem study, BCFs of <1 were measured in fish and snails for the sodium salt of 2-methyl-4-chlorophenoxyacetic acid(2,3). According to a classification scheme(3), these BCF values suggest the potential for bioconcentration in aquatic organisms is low. MCPA is absorbed through leaves or roots and is readily translocated in plants(4).
Mobility in soil
MCPA adsorption coefficients (Kd) of 0.7 to 1.0 were measured in three soils (loamy sand and sandy loam types)(1); based upon humus contents of 2.4-3.0%(1),the Koc values of the three soils are approximately 60, 52 and 50, respectively. A similar Kd value of 0.4 was observed in a garden soil(2). Using soil thin-layer chromatography, Rf values of 0.6-1.0 were measured for Chillum silt loam (3.1% organic matter), Lakeland sand loam (0.9% organic matter) and Hagerstown silty clay loam (1.4% organic matter)(3,4); these Rf values classify MCPA as mobile in soil(3,4). When MCPA was applied to a rice field, an observed 70% decrease in MCPA was attributed to losses through soil percolation(5). In a laboratory study of leaching columns with either turf grass soil or two subsoils, most of the applied MCPA (95.4-99.0%) eluted with the first 100-ml fraction of leaching water applied to the columns, indicating that MCPA did not bind to the soils(6). According to a classification scheme(7), these Koc values suggest that MCPA is expected to have high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: no data available
IMDG: no data available
IATA: no data available
UN Proper Shipping Name
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Transport hazard class(es)
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Packing group, if applicable
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/