Glyphosate SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Glyphosate
- CAS： 1071-83-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Serious eye damage, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H318 Causes serious eye damage
H411 Toxic to aquatic life with long lasting effects
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Glyphosate
- Common names and synonyms: Glyphosate
- CAS number: 1071-83-6
- EC number: 213-997-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting.
Most important symptoms/effects, acute and delayed
SYMPTOMS: Symptoms of exposure to this compound include irritation of the skin, gastrointestinal tract and respiratory tract, convulsions and coma. It may also cause enhanced breathing. ACUTE/CHRONIC HAZARDS: This compound is an irritant of the skin, respiratory tract and gastrointestinal tract. When heated to decomposition it emits very toxic fumes of nitrogen oxides and phosphorus oxides. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Glyphosate (Roundup) and Related Compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
To fight fire use/ powder, alcohol-resistant foam, water spray, carbon dioxide.
Specific hazards arising from the chemical
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Special protective actions for fire-fighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Sweep spilled substance into plastic containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Prevent build-up of electrostatic charges (e.g., by grounding). Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Do NOT store or transport in containers made from galvanized steel or unlined steel. Store in an area without drain or sewer access.Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Avoid inhalation of dust and mist.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
PHYSICAL DESCRIPTION: Odorless white powder. Decomposition begins at approximately 419°F (darkens). pH (1% solution in water) 2.5. (NTP, 1992)
-
Colour：
White crystals
-
Odour：
Odorless
-
Melting point/freezing point：
230°C
-
Boiling point or initial boiling point and boiling range：
465.8°C at 760 mmHg
-
Flammability：
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
235.5°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
<234°C
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
5 to 10 mg/mL at 64° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
-1
-
Vapour pressure：
1.94e-07 mm Hg at 113° F (NTP, 1992)
-
Density and/or relative density：
1.74
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes including nitrogen oxides and phosphorus oxides. Attacks iron and galvanized steel.
Chemical stability
Negligible volatility
Possibility of hazardous reactions
Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc.GLYPHOSATE may react with galvanized steel or unlined steel (except stainless steel) containers to produce hydrogen gas which may form a highly combustible or explosive gas mixture. It can react with caustic (basic) materials to liberate heat. It is corrosive to iron. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Incompatible materials: Strong oxidizing agents, metals, bases.
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /nitrogen and phosphorus oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Goat oral 3530 mg/kg
- Inhalation: LC50 Rat inhalation >4.98 mg/L air/4 hr
- Dermal: LD50 Rabbit percutaneous >5000 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Classification - D; not classifiable as to human carcinogenicity. Basis - Inadequate evidence for oncogenicity in animals. Glyphosate was originally classified as C, possible human carcinogen, on the basis of increased incidence of renal tumors in mice. Following independent review of the slides the classification was changed to D on the basis of a lack of statistical significance and uncertainty as to a treatment-related effect.
Reproductive toxicity
no data available
STOT-single exposure
The substance is severely irritating to the eyes. The substance is mildly irritating to the skin.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly on spraying.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: /Oncorhynchus mykiss/ (Rainbow trout) weight 0.8 g; Conditions: static bioassay without aeration, 12 deg C, pH 7.2-7.5, water hardness 40-50 mg/L as calcium carbonate and alkalinity of 30-35 mg/L Concentration: 130 mg/L for 96 hr (95% confidence interval: 108-156 mg/L) /Technical material, 96.7%
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr; Conditions: freshwater, static; Concentration: >22000 ug/L for 48 hr; Effect: intoxication, immobilization /80% purity
- Toxicity to algae: EC50; Species: Microcystis aeruginosa (Blue-Green Algae) Exponential Growth Phase; Conditions: freshwater, static, 22 deg C; Concentration: 251400 ug/L for 21 days; Effect: decreased population growth rate /formulation
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: When glyphosate was incubated in Williams silt loam soil (pH 6.4, 1.9% organic matter), 19% degradation occurred in 9 days. No degradation was noted in sterilized soil(1). In shake-flask metabolism studies, glyphosate was rapidly and completely biodegraded in the presence of soil microorganisms under both aerobic and anaerobic conditions(2). After 28 days under aerobic conditions, 45-55% of the glyphosate was mineralized using Ray silt loam soil, Lintonia sandy loam soil, and Drummer silty clay loam soil. Norfolk sandy loam mineralized glyphosate at a much slower, but still significant, rate. In greenhouse experiments, the half-lives of glyphosate in Ray, Drummer and Norfolk soil was 3, 27, and 130 days, respectively(2). The biodegradation half-life of glyphosate in a Kickapoo sandy loam and Dupo silt loam soil were 1.85 and 2.06 days, respectively, under aerobic conditions. The major degradation product observed was aminomethyl phosphonic acid. The aerobic and anaerobic biodegradation half-life of glyphosate in a flooded silty clay loam sediment was 7 and 8.1 days, respectively(3).
Bioaccumulative potential
In controlled laboratory studies using glyphosate at levels 3 to 4 times the recommended application rates, BCF values in fish tissue 10-14 days post application ranged from 0.2 to 0.3(1). A BCF value of 0.52 (whole body) was measured in bluegill (Lepomis macrochirus) exposed for 28 days(2). BCF values of 0.38 for edible tissues and 0.63 for non-edible tissues have been reported(3). According to a classification scheme(4), these BCF data suggest that bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
When applied to clay loam or muck soil at an application rate of 56 kg/ha, glyphosate was rapidly inactivated. This inactivation was probably the result of reversible adsorption to clay and organic matter. Iron and aluminum clays and organic matter adsorbed more glyphosate than sodium and calcium clays and was readily bound to kaolinite, illite, bentonite, charcoal and muck but not to ethyl cellulose. (14)C-Labeled glyphosate was degraded in soil and (14)CO2 was released.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Sodium, potassium and amine salts are readily soluble in water.Carrier solvents used in commercial formulations may change physical and toxicological properties.