Glycerol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Glycerol
- CAS： 56-81-5
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
- Signal word No signal word
none
none
none
none
none
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Glycerol
- Common names and synonyms: Glycerol
- CAS number: 56-81-5
- EC number: 200-289-5
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Rinse skin with plenty of water or shower. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Rinse mouth.
Most important symptoms/effects, acute and delayed
No hazard (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
The clinician should attend to the management of dehydration, electrolyte imbalance (hypokalemia and hyponatremia), hyperglycemia, and acidosis or alkalosis. ... Osmotic diuretics
SECTION 5: Firefighting measures
Suitable extinguishing media
Water or foam may cause frothing.
Specific hazards arising from the chemical
This chemical is combustible. (NTP, 1992)
Special protective actions for fire-fighters
Use water spray, alcohol-resistant foam, dry powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Ventilation. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Ventilation. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Wear approved respiratory protection, chemically compatible gloves and protective clothing. Wipe up spillage or collect spillage using a high efficiency vacuum cleaner. Avoid breathing vapor. Place spillage in appropriately labelled container for disposal.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants.Glycerol should preferably be stored at 40 - 60 deg C under nitrogen blanketing. It is not corrosive and presents little risk of ignition because of its high flash point. Highly concentrated glycerol does not corrode steel, but storage tanks of carbon steel must be protected by surface coating to prevent rusting by residual moisture. Glycerol is therefore usually stored in tanks of stainless steel or aluminum.
SECTION 8: Exposure controls/personal protection
Control parameters
MAK: (inhalable fraction): 200 mg/m3; peak limitation category: I(2); pregnancy risk group: C
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use ventilation.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid. Viscous.
-
Colour：
Clear, water-white.
-
Odour：
MILD ODOR
-
Melting point/freezing point：
18.17 °C. Atm. press.:Ca. 101.3 kPa.
-
Boiling point or initial boiling point and boiling range：
290 °C. Atm. press.:760 mm Hg.
-
Flammability：
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
199 °C. Atm. press.:Ca. 101.3 kPa.;177 °C. Atm. press.:Ca. 101.3 kPa.
-
Auto-ignition temperature：
370 °C. Remarks:No pressure reported. Usually autoflammability is measured at atmospheric pressure.
-
Decomposition temperature：
no data available
-
pH：
Neutral to litmus
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 1 412. Temperature:20°C.;dynamic viscosity (in mPa s) = 612. Temperature:30.0°C.;dynamic viscosity (in mPa s) = 14.8. Temperature:100.0°C.
-
Solubility：
greater than or equal to 100 mg/mL at 64° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Pow = -1.75. Temperature:25 °C.
-
Vapour pressure：
0.003 mm Hg. Temperature:50 °C.;0.195 mm Hg. Temperature:100 °C.;4.3 mm Hg. Temperature:150 °C.
-
Density and/or relative density：
1.261 g/ml. Temperature:20 °C.
-
Relative vapour density：
3.1 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces corrosive fumes of acrolein. Reacts with strong oxidants. This generates fire and explosion hazard.
Chemical stability
Mixtures of glycerin with water, ethanol (95%), and propylene glycol are chemically stable. Glycerin may crystallize if stored at low temperatures; the crystals do not melt until warmed to 20 deg C.
Possibility of hazardous reactions
GLYCERINE is incompatible with strong oxidizers. It is also incompatible with hydrogen peroxide, potassium permanganate, nitric acid + sulfuric acid, perchloric acid + lead oxide, acetic anhydride, aniline + nitrobenzene, Ca(OCl)2, CrO3, F2 + PbO, KMnO4, K2O2, AgClO4 and NaH. A mixture with chlorine explodes if heated to 158-176° F. It reacts with acetic acid, potassium peroxide, sodium peroxide, hydrochloric acid, (HClO4 + PbO) and Na2O2. Contact with potassium chlorate may be explosive. It also reacts with ethylene oxide, perchloric acid, nitric acid + hydrofluoric acid and phosphorus triiodide. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Exothermic interaction of granular /sodium/ hydride with undiluted (viscous) glycerol with inadequate stirring caused charring to occur.
Hazardous decomposition products
Pure gycerin is not prone to oxidation by the atmosphere under ordinary conditions, but is decomposes on heating with the evolution of toxic acrolein.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 12.6 g/kg
- Inhalation: LC50 Rat inhalation > 570 mg/cu m/1 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly on spraying.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 54 000 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 1 955 mg/L - 48 h.
- Toxicity to algae: EC3 - Scenedesmus quadricauda - > 10 000 mg/L - 8 d.
- Toxicity to microorganisms: Toxicity Threshold - Pseudomonas putida - > 10 000 mg/L - 16 h.
Persistence and degradability
AEROBIC: Glycerin, present at 100 mg/L, reached 63% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). Biodegradation rate constants of 0.258/day and 0.200/day in respirometric test systems employing activated sludge have also been reported, corresponding to 68% and 78% degradation, respectively(2).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for glycerin(SRC), using a log Kow of -1.76(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of glycerin can be estimated to be 1(SRC). According to a classification scheme(2), this estimated Koc value suggests that glycerin is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/