Formamide SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Formamide
- CAS： 75-12-7
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
none
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Formamide
- Common names and synonyms: Formamide
- CAS number: 75-12-7
- EC number: 200-842-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Rinse mouth. Refer for medical attention .
Most important symptoms/effects, acute and delayed
INHALATION: A moderate irritant to mucous membranes. EYES: Moderately irritating to the eyes. SKIN: A mild to moderate irritant to the skin. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Formamide is absorbed directly through guinea pig skin .
SECTION 5: Firefighting measures
Suitable extinguishing media
Fire Extinguishing Agents: Dry chemical, water, alcohol foam, or carbon dioxide. (USCG, 1999)
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Toxic fumes emitted on decomposition (carbon monoxide and ammonia), beginning at 180 - 210°C. Behavior in Fire: Vapor will burn in air above 310°F. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, alcohol-resistant foam, powder, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Store and dispose of according to local regulations.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. See Chemical Dangers. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from oxidants, acids and bases. Dry.For storage ... tanks of stainless steel or aluminum are indicated. When small amounts of iron are permissible, mild steel can be used for tank cars and drums. Caffeine, adenine and other purines stabilize formamide in storage ...
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 10 ppm as TWA; (skin).MAK skin absorption (H)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield.
Protective clothing. Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Colorless.
-
Odour：
Faint ammonia odor
-
Melting point/freezing point：
2.6 °C.
-
Boiling point or initial boiling point and boiling range：
218.3 °C. Atm. press.:1 013.3 hPa. Remarks:Normal boiling point, extrapolated.
-
Flammability：
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
152 °C. Atm. press.:1 013 hPa.
-
Auto-ignition temperature：
> 500 °C. Atm. press.:1 013 hPa.
-
Decomposition temperature：
210°C
-
pH：
7.1 (0.5 molar aqueous soln)
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 3.764. Temperature:20°C.
-
Solubility：
greater than or equal to 100 mg/mL at 66° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Pow = -0.82. Temperature:25 °C. Remarks:No information on pH available.
-
Vapour pressure：
1.001 mBar. Temperature:55.01 °C. Remarks:Lowest value measured.;0.06 hPa. Temperature:20 °C. Remarks:Extrapolated.
-
Density and/or relative density：
1.13 g/cm3. Temperature:20 °C.
-
Relative vapour density：
1.55 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes at 180°C. This produces toxic and corrosive gases including ammonia and hydrogen cyanide. Reacts with oxidants, acids and bases. This generates fire and toxic hazard. Attacks aluminium, brass, copper, iron, lead and some forms of plastic.
Chemical stability
no data available
Possibility of hazardous reactions
Combustible when exposed to heat or flame.The vapour is heavier than air.FORMAMIDE is incompatible with strong oxidizers, acids and bases. Sensitive to light. Reacts with water very slowly at room temperature, but rate is accelerated by acids and bases at elevated temperatures. Incompatible with iodine, pyridine and sulfur trioxide. Reacts explosively with furfuryl alcohol, H2O2, Tl(NO3)3.H2O, nitromethane and P2O5. An effective solvent: dissolves casein, glucose, tannins, starch, lignin, polyvinyl alcohol, cellulose acetate, nylon, the chlorides of copper, lead, zinc, tin, cobalt, iron, aluminum and nickel, the acetates of the alkali metals, some inorganic sulfates and nitrates. Attacks copper and brass (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
Incompatible with iodine, pyridine and sulfur trioxide.
Hazardous decomposition products
When heated to decomposition, emits toxic fumes of /nitrogen oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - ca. 5 325 mg/kg bw. Remarks:After 14 days.
- Inhalation: LC50 - rat (male) - > 21 mg/L air.
- Dermal: LD50 - rat (male/female) - > 3 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is moderately irritating to the eyes and skin. The substance may cause effects on the central nervous system.
STOT-repeated exposure
May cause toxicity to human reproduction or development.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Leuciscus idus - 6 569 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 500 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 500 mg/L - 72 h.
- Toxicity to microorganisms: NOEC - activated sludge from laboratory waste water plant treating municipal sewage - 1 000 mg/L - 30 min. Remarks:Respiration rate.
Persistence and degradability
AEROBIC: Theoretical BODs were measured for formamide of 1.6, 4.7, and 11.8% over 6-, 12-, and 24-hr inoculation periods(1), respectively. Theoretical BODs greater than 30% over a 2 week incubation period(2,3), and 22.6 and 57.7% over a 2 week incubation period(4) were noted using the Japanese MITI standard BOD test.
Bioaccumulative potential
An estimated BCF of 3 was calculated for formamide(SRC), using a log Kow of -1.51(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of formamide is 3.6(1). According to a classification scheme(2), this Koc value suggests that formamide is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/