N-(trichloromethylthio)phthalimide SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： N-(trichloromethylthio)phthalimide
- CAS： 133-07-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Eye irritation, Category 2
Skin sensitization, Category 1
Acute toxicity - Category 4, Inhalation
Carcinogenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H319 Causes serious eye irritation
H317 May cause an allergic skin reaction
H332 Harmful if inhaled
H351 Suspected of causing cancer
H400 Very toxic to aquatic life
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: N-(trichloromethylthio)phthalimide
- Common names and synonyms: N-(trichloromethylthio)phthalimide
- CAS number: 133-07-3
- EC number: 205-088-6
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Rinse mouth. Seek medical attention if you feel unwell.
Most important symptoms/effects, acute and delayed
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
Skin decontamination: Skin contamination should he treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be, obtained without delay. Herbicides
SECTION 5: Firefighting measures
Suitable extinguishing media
Extinguishing Media: In case of small fire: foam or dry chemical, carbon dioxide. In case of large fire: water spray, fog or regular foam. Folpan 80 WDG Fungicide
Specific hazards arising from the chemical
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)
Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: protective gloves and chemical protection suit. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: protective gloves and chemical protection suit. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Do not contaminate water by cleaning of equipment or disposal of rinsate. Folpan 80 WDG Fungicide
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. Separated from food and feedstuffs.Store in dry place at ambient or lower temperatures.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: (inhalable fraction): 1 mg/m3, as TWA; (SEN); A3 (confirmed animal carcinogen with unknown relevance to humans)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles.
Protective gloves. Protective clothing.
Use ventilation (not if powder).
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Folpet is a white crystals. Used as a fungicide. Insoluble in water.
-
Colour：
Crystals from benzene
-
Odour：
no data available
-
Melting point/freezing point：
177-180°C
-
Boiling point or initial boiling point and boiling range：
333.8°C
-
Flammability：
Combustible under specific conditions. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
155.7°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
In carbon tetrachloride 6, toluene 26, methanol 3 (all in g/L at 25 deg C)
-
Partition coefficient n-octanol/water：
log Kow = 2.85
-
Vapour pressure：
0.000133mmHg at 25°C
-
Density and/or relative density：
1.74 g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic and corrosive fumes including sulfur oxides, nitrogen oxides and hydrogen chloride (see ICSC 0163).
Chemical stability
Virtually non-volatile; stable when dry, but slowly hydrolyzes in water at ordinary temp, rapidly @ high temp or under alkaline conditions
Possibility of hazardous reactions
A halogenated phthalimide.
Conditions to avoid
no data available
Incompatible materials
Incompatible with strongly alkaline material.
Hazardous decomposition products
When heated to decomp it emits very toxic fumes of /hydrogen chloride, nitrogen oxides & sulfur oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 7540 mg/kg
- Inhalation: LC50 Rat inhalation >1.89 mg/l/4 hr
- Dermal: LD50 Rabbit (albino) percutaneous >22,600 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group B2 Probable Human
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the gastrointestinal tract. Tumours have been detected in experimental animals but may not be relevant to humans.
Aspiration hazard
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Oncorhynchus mykiss (Rainbow Trout) fingerling; Conditions: freshwater, flow through, 12 deg C, pH 7.5, hardness 314 mg/L CaCO3; Concentration: 74.0 ug/L for 24 hr (95% confidence interval: 68.6-79.9 ug/L) /88% purity technical material
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) 1st instar larvae; Conditions: freshwater, static; Concentration: 85 ug/L for 24 hr (95% confidence interval: 75-97 ug/L); Effect: intoxication, immobilization /87.5% purity
- Toxicity to algae: EC50; Species: Scenedesmus subspicatus (Green Algae); Conditions: freshwater, static; Concentration: 100 ug/L for 96 hr; Effect: population abundance /87.5% purity
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: A first-order half-life of 75.4 days was measured for the degradation of radio-labeled folpet, applied at 10 ug/L to Georgia sandy loam soil. The degradation pattern was described to be biphasic, with rapid degradation occurring between days 0-14 and slower degradation occurring between days 14-365 post-treatment. The Environmental Protection Agency calculated an integrated first-order half-life of 2.55 days using non-linear regression on the non-transformed data. An earlier study measured a half-life of 2.4 days with 74% of the applied radioactivity detected as 14CO2 at 7 days post-treatment for the degradation of radiolabeled folpet applied at 5.92 ppm to a sandy loam soil. Degradation products are carbon dioxide, phthalimide and phthalic acid(1).
Bioaccumulative potential
Bioconcentration factors (BCFs) of 19, 61, and 81 were determined for the fillet, whole fish, and viscera, respectively, in bluegill sunfish (Lepomis macrochirus)(1) using radiolabeled folpet at 10 ug/L. These bioconcentration factors are based on total radiolabeled residues and not specifically folpet residues. According to a classification scheme(2), this BCF range, based on total residues, suggests bioconcentration of folpet and its metabolites in aquatic organisms is low to moderate. The accumulated residues were eliminated over 7 days(1).
Mobility in soil
Koc values of 7.47 to 21.9 have been reported for folpet(1). According to a classification scheme(2), this estimated Koc value suggests that folpet is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3077 (For reference only, please check.)
IMDG: UN3077 (For reference only, please check.)
IATA: UN3077 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
If the pesticide is present under the form of a formulation containing hydrocarbon solvents, vomiting may not be induced.If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).Carrier solvents used in commercial formulations may change physical and toxicological properties.