Fenitrothion SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Fenitrothion
- CAS： 122-14-5
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Fenitrothion
- Common names and synonyms: Fenitrothion
- CAS number: 122-14-5
- EC number: 204-524-2
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .
Most important symptoms/effects, acute and delayed
This compound is an organophosphate insecticide. It is a highly toxic cholinesterase inhibitor, that acts on the nervous system. Does not cause delayed neurotoxicity and contact produces little irritation. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Basic Treatment: Establish a patent airway. Suction if necessary. Aggressive airway control may be needed. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary. Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Organophosphates and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Non-Specific -- Organophosphate Pesticide n.o.s.) Move containers from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Wear positive pressure breathing apparatus and special protective clothing. This compound is an organophosphate insecticide. Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog or foam. (EPA, 1998)
Specific hazards arising from the chemical
When heated to decomposition, it emits very toxic fumes of oxides of nitrogen, phosphorus and sulfur. Decomposition at 212-284F produces a mixture of organophosphorus polymers. Unstable in alkaline media. Stable for 2 years if stored at 68-77F. Do not store above 104F. (EPA, 1998)
Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: chemical protection suit including self-contained breathing apparatus. Absorb remaining liquid in sand or inert absorbent. Collect leaking liquid in covered containers. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT let this chemical enter the environment.
Environmental precautions
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Personal protection: chemical protection suit including self-contained breathing apparatus.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room./Storage temperature should be less than 40 deg C on account of the tendency/ to isomerize.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | Fenitrothion | |||
|---|---|---|---|---|
| CAS No. | 122-14-5 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Austria | ? | 1 | ? | ? |
| Japan - JSOH | ? | 1 | ? | ? |
| People's Republic of China | ? | 1 | ? | 2 (1) |
| Poland | ? | 0,02 | ? | 0,1 |
| Remarks | ||||
| People's Republic of China | (1) 15 minutes average value | |||
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Fenitrothion is a brownish-yellow oil. Used as a selective acaricide and a contact and stomach insecticide against chewing and sucking insects on rice, orchard fruits, vegetables, cereals, cotton and forest. Also used against flies, mosquitoes, and cockroaches. (EPA, 1998)
-
Colour：
Yellow-brown liquid
-
Odour：
Phenolic odor
-
Melting point/freezing point：
3.4°C
-
Boiling point or initial boiling point and boiling range：
140-145°C (0.05 torr)
-
Flammability：
Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
165.2°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
140-145°C
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Readily soluble in dichloromethane, 2-propanol, toluene, hardly sol in n-hexane.
-
Partition coefficient n-octanol/water：
log Kow= 3.30
-
Vapour pressure：
0mmHg at 25°C
-
Density and/or relative density：
1.3227
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides, phosphorus oxides and sulfur oxides.
Chemical stability
It is hydrolyzed by alkali, in 10 m sodium hydroxide 50% loss occurs in 4.5 hr @ 30 deg c
Possibility of hazardous reactions
Organophosphates, such as FENITROTHION, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat (female) acute oral 800 mg/kg
- Inhalation: no data available
- Dermal: LD50 Rat (male) acute percutaneous 890 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the nervous system. This may result in convulsions, respiratory failure and death. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Rainbow trout 2.4 mg/l/96 hr, water 10 deg C (95% confidence limit 2.0-2.9 mg/l), wt 1.5 g. Static bioassay without aeration, pH 7.2-7.5, water hardness 40-50 mg/l as calcium carbonate and alkalinity of 30-35 mg/l. Technical material, 95%.
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
The loss of fenitrothion was faster in non-sterile soil than sterile soil indicating degradation in soil was a combination of abiotic and microbial reactions(1). The rate of fenitrothion degradation in soil depended on pH, soil type, organic amendment, soil moisture content and pesticide concentration(1). The half-life was 1608 days in a non-sterile sandy loam soil containing 1,000 ppm fenitrothion at a soil pH 7.2 and moisture content of 50%(1). On the other hand, the biodegradation half-life was 13 days in a non-sterile clay loam soil containing 100 ppm fenitrothion at a soil pH 10 and moisture content of 50%(1).
Bioaccumulative potential
There were no consistent differences in concn of fenitrothion in streamwater with depth, or between midstream and slow water at the stream edge. This was true of aq and oil-based formulations. A large portion of the fenitrothion was taken up by suspended material; in sediment, it was taken up mainly by the organic fraction. Concn of fenitrothion were above pre-spray values in most plants and insects sampled, and in some, above peak concn found in the water. Highest and most persistent residues were found in a livewort. Highest residues in an animal were found in black fly larvae, perhaps explained by their filter-feeding on suspended matter with high fenitrothion concn. Peak concn in plants and animals usually occured at 6 or 24 hr postspray sampling times, and in all cases decr thereafter. Aminofenitrothion and fenitrooxon in sediments and 3-methyl-4-nitrophenol in plants and insects were seldom and inconsistently detected.
Mobility in soil
Measured fenitrothion Koc values of 593 and 254 in Tsukuba and Kanuma soils(1) and 1531, 1201, 833, and 1061 in 4 rice soils(2) have been determined. According to a classification scheme(3), these Koc value suggests that fenitrothion is expected to have low to moderate mobility in soil. A study conducted on organic and silty clay loam soil, from the Boreal Forest in Ontario, Canada, indicate a maximum adsorption rate of 92 ug/g and 81 ug/g, respectively, in 30 hrs when fenitrothion-acetone is added to the soils(4). In the same experiment, studies with a buffer solution showed 38 and 48% desorption rate after 50 hrs extraction time(4).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3018 (For reference only, please check.)
IMDG: UN3018 (For reference only, please check.)
IATA: UN3018 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.