Ethoprophos SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Ethoprophos
- CAS： 13194-48-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 1, Dermal
Skin sensitization, Category 1
Acute toxicity - Category 2, Inhalation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H301 Toxic if swallowed
H310 Fatal in contact with skin
H317 May cause an allergic skin reaction
H330 Fatal if inhaled
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
P391 Collect spillage.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Ethoprophos
- Common names and synonyms: Ethoprophos
- CAS number: 13194-48-4
- EC number: 236-152-1
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. Wear protective gloves when administering first aid.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.
Most important symptoms/effects, acute and delayed
This material is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150 lb. person. It is a cholinesterase inhibitor which affects the nervous system. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Airway protection. Ensure that a clear airway exists. Intubate the patients and aspirate the secretions with a large-bore suction device if necessary. Administer oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. Improve tissue oxygenation as much as possible before administering atropine, so as to minimize the risk of ventricular fibrillation. In severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. Organophosphate pesticides
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide. Organophosphorus pesticides, liquid, flammable, toxic; Organophosphorus pesticides, liquid, toxic
Specific hazards arising from the chemical
Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Stable in water. Hydrolyzed in alkali. (EPA, 1998)
Special protective actions for fire-fighters
Use water spray, dry powder, carbon dioxide, alcohol-resistant foam. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Environmental precautions
Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Methods and materials for containment and cleaning up
Environmental considerations: Air spill: Apply water spray or mist to knock down vapors. Organophosphorus pesticides, liquid, flammable, toxic; Organophosphorus pesticides, liquid, toxic; Organophosphorus pesticides, solid, toxic
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access. Ventilation along the floor.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV BEI issued
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Ethorop is one of a family of organophosphorus pesticides. It is combustible though it may require some effort to ignite. It is very toxic by skin absorption and inhalation. It may or may not be water soluble.
-
Colour：
Pale yellow liquid
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Odour：
no data available
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Melting point/freezing point：
-13°C
-
Boiling point or initial boiling point and boiling range：
86-91°C
-
Flammability：
Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Heating will cause rise in pressure with risk of bursting.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
100°C
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Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
Readily sol in most organic solvents
-
Partition coefficient n-octanol/water：
log Kow = 3.59 @ 21 deg C
-
Vapour pressure：
0.00111mmHg at 25°C
-
Density and/or relative density：
1.106g/cm3
-
Relative vapour density：
(air = 1): 8.4
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes at room temperature. This produces flammable n-propylmercaptan (see ICSC 1492). Decomposes on heating. This produces toxic fumes including phosphorus oxides and sulfur oxides.
Chemical stability
Very stable in neutral and weakly acidic media. Rapidly hydrolysed in alkaline media. Stable in water up to 100 deg C at pH 7.
Possibility of hazardous reactions
Organothiophosphates, such as ETHOPROPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Conditions to avoid
no data available
Incompatible materials
Incompatible with alkaline materials.
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /phosphorus oxides and sulfur oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral (male) 61 mg/kg
- Inhalation: no data available
- Dermal: LD50 Rabbit percutaneous 26 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Likely to be Carcinogenic to Humans
Reproductive toxicity
no data available
STOT-single exposure
Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Exposure could cause death. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Lepomis macrochirus (Bluegill) 2.07 mg/l/96 hr /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
During ethoprop metabolism studies, it was observed that ethoprop did not metabolize in sterilized soils, but did in nonsterile soils(1). Soil from ethoprop treated plots in the Midwestern US were studied to determine ethoprop persistence(1); half-lives of 5-12 days were observed at application rates of 1-2 lb/acre granular formulation(1); when applied as a liquid formulation to VA soil, half-lives of 3-4 days were observed(1). Addition of ethoprop to soil has been observed to stimulate microbial oxygen consumption(2). During 4-week soil incubation studies using 1-ethyl-14C-labeled ethoprop, (14)CO2 evolution ranged from 23.4 to 50.9% in soils having no previous organophosphorus exposure and soils having prior exposure to isofenphos and fonophos(3); (14)CO2 from ethoprop was greater in soil having no prior exposure to the other pesticides(3). Mineralization of ethoprop was found to occur faster in soils that had been treated previously with ethoprop as compared to no prior treatment indicating microbial adaptation(4); during a 1 wk incubation, 32.7% mineralized in previously treated soil and 19.9% mineralized in untreated soil(4). Faster biodegradation in previously ethoprop treated soils was also noted in another study(5); sterilization of soils drastically reduced disappearance rates of ethoprop(5). The soil half-life of ethoprop can range from 3 to 56 days(6). In various field studies, soil half-lives of 2-12 weeks were determined(7). In soil column studies, ethoprop had the following half-lives(8): in silty loam (12 days at 20 deg C to 89 days at 2 deg C), in sandy loam (16 days at 20 deg C to 144 days at 2 deg C), in humous loamy sand (73 days at 20 deg C to 347 days at 6 deg C)(8). The half-lives of ethoprop in sterile and non-sterile soil from a banana plantation in Jamaica, with heavy ethoprop use, were 28.8 and 10.9 days, respectively(9).
Bioaccumulative potential
Using an intermittent flow-through system, an ethoprop BCF range of 4 to 17 was measured in juvenile sheepshead minnow over a 28 day exposure period(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
In adsorption studies using silty clay loam, silt loam and two sandy loam soils, ethoprop adsorption was found to increase as soil organic matter increased(1); adsorption was to a great extent reversible indicating that the major interaction between ethoprop and the adsorptive surfaces was hydrophobic bonding(1); experimentally determined Koc values (values not reported) place ethoprop in the medium soil mobility class(1). The US Dept Agric's Pesticide Properties Database lists a Koc value of 70 for ethoprop(2). Koc values of 120.6 and 76.0 have been reported for Riverhead and Rhinebeck soils, respectively(3). According to a classification scheme(4), these Koc values suggest that ethoprop is expected to have high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3018 (For reference only, please check.)
IMDG: UN3018 (For reference only, please check.)
IATA: UN3018 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.The substance is combustible but no flash point is available in literature.Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Carrier solvents used in commercial formulations may change physical and toxicological properties.