O-ethyl O-4-nitrophenyl phenylphosphonothioate SDS

Acute toxicity - Category 2, Oral

Acute toxicity - Category 1, Dermal

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H300 Fatal if swallowed

H310 Fatal in contact with skin

H410 Very toxic to aquatic life with long lasting effects

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P262 Do not get in eyes, on skin, or on clothing.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P273 Avoid release to the environment.

P301+P316 IF SWALLOWED: Get emergency medical help immediately.

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P316 Get emergency medical help immediately.

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P391 Collect spillage.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. Wear protective gloves when administering first aid. Put clothes in sealable container. See Notes.

Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.

This material may be fatal if swallowed. It is poisonous if inhaled and extremely hazardous by skin contact. Repeated exposure may, without symptoms, be increasingly hazardous. The estimated fatal oral dose is 0.3 grams for a 150 lb. (70 kg) person. (EPA, 1998)

Basic treatment: Establish a patent airway. Suction if necessary. Aggressive airway control may be needed. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Organophosphates and related compounds

Self contained breathing apparatus with a full facepiece operated in pressure demand, or other positive pressure mode /should be used in firefighting/. Parathion

Non-Specific -- Organophosphorus Pesticide, n.o.s.) This material may burn but does not ignite readily. Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Avoid strong oxidizers. Hydrolyzed by alkali. (EPA, 1998)

Use powder, alcohol-resistant foam, water spray, carbon dioxide.

Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.

Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.

1) Ventilate area of spill. 2) Cover with soda ash, mix and spray with water. Place in container of water and allow to stand for two days, then neutralize with 6 molar hydrogen chloride.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from strong oxidizers and food and feedstuffs. Well closed. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Keep away from heat and open flame. Keep container closed. Store at 65-100 deg F.

TLV: (inhalable fraction): 0.1 mg/m3, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued.MAK: (inhalable fraction): 0.5 mg/m3; peak limitation category: II(2); skin absorption (H)

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield or eye protection in combination with breathing protection if powder. Wear safety spectacles.

Protective gloves. Protective clothing.

Use local exhaust or breathing protection.

no data available

Decomposes on heating. This produces toxic and corrosive fumes including nitrogen oxides, phosphorus oxides and sulfur oxides. Reacts with strong oxidants strong oxidants. This generates fire and explosion hazard. Decomposes under the influence of bases. This produces p-nitrophenol (see ICSC 0066).

Stable in neutral and acidic media but hydrolyzed by alkali to liberate p-nitrophenol.

Organophosphates, such as EPN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

no data available

Strong oxidizers

The substance decomposes under influence of alkalies (hydrolysis) forming p-nitrophenol

no data available

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A4; Not classifiable as a human carcinogen.

no data available

The substance is irritating to the eyes and skin. Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Exposure could cause unconsciousness and death. The effects may be delayed. Medical observation is indicated.

Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

A harmful concentration of airborne particles can be reached quickly.

AEROBIC: EPN, present at 100 mg/l, reached 3% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/l and the Japanese MITI test(1). Field dissipation half-lives ranging from 28 to 56 days have been reported(2). The half-life of 14C-labeled EPN in field tests with Dundee silt loam (pH 5.5, organic matter 1.3%) and Keyport silt loam (pH 6.4, organic matter 2.75%) were 2 weeks and 1 month, respectively(3) Greater than 90% of the residual radiolabeled carbon was found in the top 3 inches of soil, after 18 months, indicating no leaching of EPN or its degradation products had occurred(3). Under greenhouse conditions 14C-labeled EPN has a half-life of 5-6 weeks in Fallsington sandy loam soil (pH 5.6, organic matter 1.4%)(3). In a biometer study with Keyport silt loam half-lives were 5 and 6 weeks at 2 and 10 ppm, respectively(3). Breakdown of EPN in soil proceeded primarily through hydrolysis and oxidation to phenylphosphonic acid, followed by further degradation of the phenyl ring to CO2(3). Under laboratory conditions, the half-life of 1 ppm EPN in upland soil was 30-90 days and in submerged soil it was 3-15 days(4). In upland soils, degradation products were EPN-oxon, desethyl EPN-oxon, O-ethyl S-methylphenylphosphonothiolate, p-nitrophenol, O-ethyl O-methylphenylphosphonate, O-ethylphenylphosphonate, and phenylphosphonic acid(4).

BCF values of 2,346(1), 700(2), 2,100 to 7,700(3), 358 to 1590(4), 1682(5), 495(6) to 1205(7), 929 to 1116(7), 641(7), 376(7) in topmouth gudgeon, pinfish, adult sheepshead minnow, carp, willow shiner, killifish, guppy, goldfish, and white cloud mountain fish, respectively, have been reported. According to a classification scheme(8), these BCF values suggest the potential for bioconcentration in aquatic organisms is high to very high(SRC). Although EPN can be bioconcentrated in aquatic organisms, it is also rapidly depurated(2). Pinfish exposed to 2.4 ug/l EPN, bioconcentrated the compound rapidly, reaching an apparent steady-state in approximately 2 days(2). After a 4-day post-exposure period only 1 out of 4 pinfish had detectable levels of EPN (0.04 g/g) in its tissues and after 8 days EPN was not detected in any fish(2). EPN was applied to sorghum leaves in a terrestrial-aquatic model ecosystem containing salt marsh catepillars, mosquito larvae, plankton, alga, snails and fish. After 33 days the values for bioaccumulation or ecological magnification in snail and fish were reported as 12,561 and 346, respectively(3).

Koc values, measured at concentrations of 0.01, 0.1 and 1.0 ppm EPN, were 1,997 and 706 for a clay loam and a high clay soil, respectively, with a mean of 1,327(1). According to a classification scheme(2), these Koc values suggest that EPN is expected to have low mobility in soil. In field tests with Dundee silt loam (pH 5.5, organic matter 1.3%) and Keyport silt loam (pH 6.4, organic matter 2.75%), greater than 90% of the residual radiolabeled carbon was found in the top 3 inches of soil, after 18 months, indicating no leaching of EPN or its degradation products had occurred(3).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN3018 (For reference only, please check.)

IMDG: UN3018 (For reference only, please check.)

IATA: UN3018 (For reference only, please check.)

ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)

IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)

IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

ADR/RID: I (For reference only, please check.)

IMDG: I (For reference only, please check.)

IATA: I (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

no data available

Depending on the degree of exposure, periodic medical examination is suggested.Isolate contaminated clothing by sealing in a bag or other container.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.