Diuron SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Diuron
- CAS： 330-54-1
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Carcinogenicity, Category 2
Specific target organ toxicity – repeated exposure, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H351 Suspected of causing cancer
H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Diuron
- Common names and synonyms: Diuron
- CAS number: 330-54-1
- EC number: 206-354-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
INHALATION: May cause irritation of nose and throat. EYES: Irritation. SKIN: Moderately irritating to skin. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
SECTION 5: Firefighting measures
Suitable extinguishing media
Use dry chemical, CO2, water spray, or foam extinguishers ... If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors or shows any digns of deforming), withdraw immediately to a secure position ... The only respirators recommended for fire fighting are self-contained breathing apparatuses that have full face-pieces and are operated in a pressure-demand or other positive-pressure mode.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Highly toxic fumes are imminent Behavior in Fire: Decomposes at 180° to 190°C (USCG, 1999)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Spill handling: evacuate persons not wearing protective equipment from area of spill or leak until clean-up is complete. Remove all ignition sources. Collect powdered material in the most convenient and safe manner and deposit in sealed containers. Ventilate area after clean-up is complete. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store in tightly closed containers in a cool, well-ventilated area.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | Diuron | |||
|---|---|---|---|---|
| CAS No. | 330-54-1 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Australia | ? | 10 | ? | ? |
| Austria | ? | 5 inhalable aerosol | ? | 10 inhalable aerosol |
| Belgium | ? | 10 | ? | ? |
| Canada - Ontario | ? | 10 | ? | ? |
| Canada - Québec | ? | 10 | ? | ? |
| Denmark | ? | 5 | ? | 10 |
| Finland | ? | 10 | ? | 20 (1) |
| France | ? | 10 | ? | ? |
| Ireland | ? | 10 | ? | ? |
| New Zealand | ? | 10 | ? | ? |
| People's Republic of China | ? | 10 | ? | ? |
| Singapore | ? | 10 | ? | ? |
| South Korea | ? | 10 | ? | ? |
| Spain | ? | 10 | ? | ? |
| Switzerland | ? | 10 inhalable aerosol | ? | ? |
| USA - NIOSH | ? | 10 | ? | ? |
| United Kingdom | ? | 10 | ? | ? |
| Remarks | ||||
| Finland | (1) 15 minutes average value | |||
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Diuron is a white crystalline solid. It is a wettable powder. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It can cause illness by inhalation, skin absorption and/or ingestion. It is used as a herbicide.
-
Colour：
White, crystalline solid
-
Odour：
Odorless
-
Melting point/freezing point：
280°C(lit.)
-
Boiling point or initial boiling point and boiling range：
158°C/11mmHg(lit.)
-
Flammability：
Noncombustible Solid
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
103°C(lit.)
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
0.004 % (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
log Kow = 2.68
-
Vapour pressure：
2e-09 mm Hg (NIOSH, 2016)
-
Density and/or relative density：
1.369 g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Very slightly soluble in water.
Chemical stability
Stable for 2 yrs. in double polyethylene bag inside a fiber drum under warehouse conditions.
Possibility of hazardous reactions
May burn, but not readily flammable.DIURON is incompatible with the following: Strong acids (NIOSH, 2016).
Conditions to avoid
no data available
Incompatible materials
Treatment at elevated temperatures by acid or base yields dimethylamine and 3,4-dichloroaniline.
Hazardous decomposition products
Diuron, stable under normal conditions, decomposed on heating to 180 to 190 deg C giving dimethylamine and 3,4-dichlorophenyl isocyanate.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat (male) oral 3400 mg/kg
- Inhalation: LC50 Rat inhalation > 0.265 mg/L for 4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Known/ Likely to be Carcinogenic to Humans
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill), weight 0.8 g; Concentration: 8.2 mg/L/96 hr (95% confidence limit 7.4 - 9.1 mg/L); Conditions: static bioassay without aeration, temperature 18 deg C, pH 7.2-7.5, water hardness 40-50 mg/L as calcium carbonate, alkalinity 30-35 mg/L
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (water flea); Concentration: 1400 ug/L/24 hr /Conditions of bioassay not specified
- Toxicity to algae: LC50; Species: Scenedesmus subspicatus (algae); Concentration: 0.022 mg/L for 4 days; Conditions: temperature 23 deg C
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Diuron, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). In a Zahn-Wellens inherent biodegradability test, 50 mg/L of diuron was found to be not inherently biodegradable with 0% degradation in activated sludge inoculum after 28 days(2). Degradation of diuron in natural soils was found to be slow and incomplete(3). Inoculation of a sandy C-horizon with a diuron-degrading bacterial strain led to substantial diuron degradation, but the addition of purified fulvic acid and humic acid to these inoculated soils decreased this degradation, suggesting that adsorption to humic substances in soil hinders degradation(3). In soil, enzymatic and microbial demethylation of the nitrogen atom and hydroxylation at position 2 of the benzene ring occurs. Duration of activity in soil is about 4 to 8 months, depending on soil type and humidity, with a half-life of 90 to 180 days(4). In a 22 week laboratory study conducted at 27 deg C and 60% relative humidity, approximately 40% degradation occurred in Cecil loamy sand (1 ppm applied 4 times) and Brookstone silty clay loam (5 ppm applied 4 times)(5). Biological degradation in soil increased with increasing temperature and decreased with increasing concentration; little degradation was noted at 0 deg C in 20 weeks whereas substantial degradation occurred in 10 weeks in two soils at 10 ppm and only in one at 15 ppm when incubated at 20 deg C(6,7). Less than 20% of diuron (60 ppm) added to soil was detoxified within 8 weeks and there was little effect on the degradation rate when the soils were titrated to different pH's between 4.3 and 7.5(8). Degradation of diuron in soil was stimulated by amendment of the soil with manure but inhibited by sludge amendment(9).
Bioaccumulative potential
BCF values of 3.4 to 4.9 and <2.9 to 14 were measured in fish for diuron at concentrations of 0.5 and 0.05 mg/L, respectively, using carp (Cyprinus carpio) which were exposed over an 6-week period(1). According to a classification scheme(2), these BCF values indicate that bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The mean value and standard deviation of Koc for diuron compiled from the published literature for 84 soils is 383 and 72 respectively(1). Other Koc experimental values for diuron are: Webster soil, 682(2); mucky peat soil, 879(3); loamy sand soil, 478(3); two subsurface soils from Oklahoma, 224 and 371(4); 480 (5); 400 (6); aquifer sediments, range 69-266(7). In 43 surface soil samples representing a range of soil physicochemical properties collected from dry and wet zones of Sri Lanka, measured Koc values for diuron ranged from 55.3 to 962 (mean, 407; median, 328), while soils from dry zones were 1.5 times higher than those from the wet zone(8). In three representative cotton soils, a red sandy soil, a black cracking clay, and a brown loam, of North West New South Wales, Australia, diuron had Koc values of 457, 488, and 498, respectively(9). According to a classification scheme(10), these measured Koc values suggest that diuron is expected to have moderate to low mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/