Dimethylamine SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Dimethylamine
- CAS： 124-40-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Gases under pressure: Liquefied gas
Flammable gases, Category 1A, Flammable gas
Skin irritation, Category 2
Serious eye damage, Category 1
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H220 Extremely flammable gas
H315 Causes skin irritation
H318 Causes serious eye damage
H332 Harmful if inhaled
H335 May cause respiratory irritation
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P381 In case of leakage, eliminate all ignition sources.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P403 Store in a well-ventilated place.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Dimethylamine
- Common names and synonyms: Dimethylamine
- CAS number: 124-40-3
- EC number: 204-697-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
VAPOR: Irritating to eyes, nose and throat. If inhaled, will cause difficult breathing. LIQUID. Will burn skin and eyes. Harmful if swallowed. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 mg/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Cover skin burns with dry sterile dressings after decontamination . /Organic bases/Amines and related compounds/
SECTION 5: Firefighting measures
Suitable extinguishing media
Stop flow of gas before extinguishing fire. Use water spray to keep fire-exposed containers cool. Use water spray, dry chemical, or "alcohol resistant" foam on fires involving aqueous solutions.
Specific hazards arising from the chemical
FLAMMABLE. Flashback along vapor trail may occur. May explode if ignited in an enclosed area. Vapors are eye, skin and respiratory irritants. (USCG, 1999)
Special protective actions for fire-fighters
Use water in large amounts, alcohol-resistant foam, dry powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Cover the spilled material with foam. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT let this chemical enter the environment.
Environmental precautions
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Remove all ignition sources. NEVER direct water jet on liquid. Remove gas with fine water spray. Do NOT let this chemical enter the environment.
Methods and materials for containment and cleaning up
Environmental considerations-land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Apply "universal" gelling agent to immobilize spill. Neutralize with sodium bisulfate (NaHSO4). Dimethylamine, Solution
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Cool.They are extremely flammable products that should be stored in a well-ventilated area and protected from fire risk. Methylamines
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 5 ppm as TWA; 15 ppm as STEL; (SEN); A4 (not classifiable as a human carcinogen).MAK: 3.7 mg/m3, 2 ppm; peak limitation category: I(2); pregnancy risk group: D.EU-OEL: 3.8 mg/m3, 2 ppm as TWA; 9.4 mg/m3, 5 ppm as STEL
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Dimethylamine, anhydrous is a colorless gas smelling of fish at low concentrations and of ammonia at higher concentrations. Shipped as a liquid under its vapor pressure. Contact with the unconfined liquid can cause frostbite by evaporative cooling and chemical type burns. Density of liquid 5.5 lb / gal. The gas, which is corrosive, dissolves readily in water to form flammable corrosive solutions. The gas is heavier than air and can asphyxiate by the displacement of air. Gas is easily ignited and produces toxic oxides of nitrogen when burned. Long-term inhalation of low concentrations or short-term inhalation of low concentrations has adverse health effects. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. Used to make other chemicals and as a solvent.
-
Colour：
Colorless gas ... [Note: A liquid below 44 degrees F. Shipped as a liquefied compressed gas].
-
Odour：
... Ammonia or fish-like odor ...
-
Melting point/freezing point：
-93°C
-
Boiling point or initial boiling point and boiling range：
7°C(lit.)
-
Flammability：
Flammable Gas
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 2.8% by volume; Upper flammable limit: 14.4% by volume
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Flash point：
-6°C
-
Auto-ignition temperature：
753°F
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Decomposition temperature：
no data available
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pH：
AQUEOUS SOLN OF DIMETHYLAMINE ARE HIGHLY ALKALINE, LIKE AMMONIA.
-
Kinematic viscosity：
1.7 mPa.s at 15.5 deg C /40% Dimethylamine aqueous solution/
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Solubility：
24 % at 140° F (NIOSH, 2016)
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Partition coefficient n-octanol/water：
log Kow = -0.38
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Vapour pressure：
16.97 psi ( 55 °C)
-
Density and/or relative density：
0.68g/mLat 20°C(lit.)
-
Relative vapour density：
1.55 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on burning. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants and mercury. This generates fire and explosion hazard. Attacks copper, zinc alloys, aluminium, galvanized surfaces and plastics. The solution in water is a strong base. It reacts violently with acid and is corrosive (see ICSC 1485 dimethylamine, aqueous solution).
The solution in water is a strong base. It reacts violently with acid and is corrosive. Reacts violently with strong oxidants and mercury. This generates fire and explosion hazard. Attacks aluminium, copper, zinc alloys, galvanized surfaces and plastic.
Chemical stability
no data available
Possibility of hazardous reactions
Liquid solutions are flammable.The gas is heavier than air and may travel along the ground; distant ignition possible.,The vapour is heavier than air and may travel along the ground; distant ignition possible.DIMETHYLAMINE is a base, neutralizing acids in exothermic reactions, and a reducing agent. It is temperature sensitive. Reacts vigorously with mercury and chlorine (NTP, 1992). Reacts violently with strong oxidizing agents and attacks copper and copper compounds [Handling Chemicals Safely, 1980 p. 123]. Reacts with hypochlorites to give N-chloroamines, some of which are explosives when isolated [Bretherick, 1979 p. 108].
Conditions to avoid
no data available
Incompatible materials
Dimethylamine is a medium strong base. Reacts violently with strong oxidizers; with mercury causing fire and explosion hazard. Incompatible with acids, organic anhydrides, isocyanates, vinyl acetate, acrylates, substituted allyls, alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks aluminum, copper, lead, tin, zinc and alloys, some plastics, rubber and coatings.
Hazardous decomposition products
Products of decomposition include carbon monoxide, carbon dioxide, hydrocarbons, and toxic oxides of nitrogen as well as toxic amine vapors.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 698 mg/kg
- Inhalation: LC50 Mouse inhalation (2 hr) 14.3 mg/L
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4; Not classifiable as a human carcinogen.
Reproductive toxicity
no data available
STOT-single exposure
The substance is corrosive to the eyes and skin. The vapour is severely irritating to the respiratory tract. Corrosive on ingestion.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air will be reached very quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Brachydanio rerio /Zebra danio/ 396 mg/L/96 hr; static, freshwater. /Dimethylamin-Hydrochlorid
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea); Conditions: freshwater, static, 15 deg C, pH 7.2, hardness 320 mg/L CaCO3, dissolved oxygen >95%; Concentration: 46,000 ug/L for 96 hr (95% confidence interval: 40,100-52,800 ug/L); Effect: intoxication, immobilization
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae); Conditions: freshwater, static; Concentration: 9000 ug/L for 96 hr; Effect: general growth /40% water solution
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: 51% of the theoretical BOD was achieved for dimethylamine with an activated sludge during a 2 week incubation period(1). Dimethylamine was biodegraded 69-89% in three Saskatchewan soils during a 7 day incubation period(2). In a screening study, dimethylamine completely degraded at 10 ppm with both an activated sludge and freshwater/sediment inoculum(3); after 5 days incubation, 70 and 80% of theoretical BOD was consumed in the activated sludge and the sediment, respectively(1). Inhibition was noted at 50 ppm with the sediment inoculum and 100 ppm with the sludge inoculum(3). Another screening study that employed an activated sludge inoculum reported 100% degradation in 6 and 12 days when the concentration was 20 mg/L and 135 mg/L, respectively(4). Other screening studies give similar results and dimethylamine is confirmed to be biodegradable according to the standard test of the Japanese Ministry of Industry and Trade (MITI) that employs a mixed inoculum obtained from freshwater, soil, and sludge(5-7). In a laboratory activated sludge unit, dimethylamine was completely removed from inflows of up to 135 mg/L with retention times of 4 hr indicating that it should be readily degraded in biological treatment plants(4). When 250 ppm dimethylamine was added to a fine sand loam and sandy soil amended with sewage and nitrite-N, 50% degradation occurred in 2 days in the sand loam, while 20% degradation occurred in the sandy soil(8). N-nitrosodimethylamine was formed in the degradation(8). 50 to >90% degradation occurred in four silt loam or loam soils within 14 days(9).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for dimethylamine(SRC), using a log Kow of -0.38(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The adsorption isotherm for dimethylamine in 5 soils was linear and resulted in a mean Koc of 434.9(1). A Koc value of 508 was reported for dimethylamine in lake sediment(2). According to a classification scheme(3), this Koc data suggests that dimethylamine is expected to have moderate mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1160 (For reference only, please check.)
IMDG: UN1160 (For reference only, please check.)
IATA: UN1160 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: DIMETHYLAMINE AQUEOUS SOLUTION (For reference only, please check.)
IMDG: DIMETHYLAMINE AQUEOUS SOLUTION (For reference only, please check.)
IATA: DIMETHYLAMINE AQUEOUS SOLUTION (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Toxicity information applies to aqueous solutions containing dimethylamine over 15%, and physical properties will vary according to concentration.Physical properties of this card are for the 40% solution.See ICSC 0260 Dimethylamine gas in a cylinder.