Diethyl ether SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Diethyl ether
- CAS： 60-29-7
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 1
Acute toxicity - Category 4, Oral
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H224 Extremely flammable liquid and vapour
H302 Harmful if swallowed
H336 May cause drowsiness or dizziness
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Diethyl ether
- Common names and synonyms: Diethyl ether
- CAS number: 60-29-7
- EC number: 200-467-2
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Vapor inhalation may cause headache, nausea, vomiting, and loss of consciousness. Contact with eyes will be irritating. Skin contact from clothing wet with the chemical may cause burns. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
INHALATION: Cough. Sore throat. Drowsiness. Vomiting. Headache. Labored breathing. Unconsciousness. First aid: Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. SKIN: Symptoms: Dry skin. First aid: Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES: Symptoms: Redness. Pain. First aid: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION: Symptoms: Dizziness. Drowsiness. Vomiting. First aid: Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.
SECTION 5: Firefighting measures
Suitable extinguishing media
Water may be ineffective ... But water should be used to keep fire-exposed containers cool. Use water spray dry chemical, foam, or carbon dioxide.
Specific hazards arising from the chemical
Behavior in Fire: Vapor is heavier than air and may travel considerable distance to a source of ignition and flash back. Decomposes violently when heated. (USCG, 1999)
Special protective actions for fire-fighters
Use alcohol-resistant foam, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Spills and leakage: Absorb with paper. Evaporate completely all spilt surface. Dispose by burning the paper after complete ventilation of vapor.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants. See Chemical Dangers. Cool. Keep in the dark. Store only if stabilized.Separate from oxidizing materials. Store in a cool, dry, well-ventilated area. Avoid sunlight.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 400 ppm as TWA; 500 ppm as STEL.MAK: 1200 mg/m3, 400 ppm; peak limitation category: I(1); pregnancy risk group: D.EU-OEL: 308 mg/m3, 100 ppm as TWA; 616 mg/m3, 200 ppm as STEL
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid. Liquid.
-
Colour：
Colourless.
-
Odour：
Sweetish, pungent odor
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Melting point/freezing point：
-116.3 °C. Remarks:Melting point for stable crystals.
-
Boiling point or initial boiling point and boiling range：
34.58 - 34.59 °C. Atm. press.:760 mm Hg.
-
Flammability：
Class IA Flammable Liquid: Fl.P. below 73°F and BP below 100°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 1.9% by volume; Upper flammable limit: 36.0% by volume
-
Flash point：
-44.37°C. Atm. press.:1 atm.;-14.43°C. Atm. press.:1 atm.
-
Auto-ignition temperature：
175 °C. Atm. press.:Ca. 1 atm.
-
Decomposition temperature：
no data available
-
pH：
no data available
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Kinematic viscosity：
dynamic viscosity (in mPa s) = 0.235. Temperature:20°C. Remarks:Pressure 100 kPa.;dynamic viscosity (in mPa s) = 0.195. Temperature:40°C. Remarks:Pressure 410 kPa.;dynamic viscosity (in mPa s) = 0.203. Temperature:40°C. Remarks:Pressure 4360 kPa.
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Solubility：
greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
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Partition coefficient n-octanol/water：
Pow = 6.8. Temperature:20 °C.
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Vapour pressure：
58.96 kPa. Temperature:20°C. Remarks:Calculated from fitted experimental data.;589.6 hPa. Temperature:20 °C. Remarks:Calculated from fitted experimental data.;71.6 kPa. Temperature:25°C. Remarks:Calculated from fitted experimental data.
-
Density and/or relative density：
0.71 g/cm3. Temperature:20 °C.;0.73 g/cm3. Temperature:10 °C.;0.74 g/cm3. Temperature:0 °C.
-
Relative vapour density：
2.6 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
1900 ppm [Based on 10% of the lower explosive limit for safety considerations even though the relevant toxicological data indicated that irreversible health effects or impairment of escape existed at higher concentrations.]
The substance can form explosive peroxides under the influence of light and air. Reacts violently with halogens, interhalogens, sulfur compounds and oxidants. This generates fire and explosion hazard. Attacks plastics and rubber.
Chemical stability
It is slowly oxidized by action of air, moisture, and light, with formation of peroxides.
Possibility of hazardous reactions
When shaken under absolutely dry conditions ether can generate enough static electricity to start a fire.The vapour is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated.Occasional explosions have occurred when aluminum hydride was stored in ether. The explosions have been blamed on the presence of carbon dioxide impurity in the ether, [J. Amer. Chem. Soc. 70:877(1948)]. Diethyl ether and chromium trioxide react violently at room temperature. Solid acetyl peroxide in contact with ether or any volatile solvent may explode violently. A 5-gram portion in ether detonated while being carried, [Chem. Eng. News 27:175(1949)]. Nitrosyl perchlorate ignites and explodes with diethyl ether. A mixture of ether and ozone forms aldehyde and acetic acid and a heavy liquid, ethyl peroxide, an explosive, [Mellor 1:911(1946-1947)].
Conditions to avoid
no data available
Incompatible materials
Boron triazide, bromine trifluoride, bromine pentafluoride, bromine, iodine heptafluoride, silver perchlorate, fluorine nitrate, permanganic acid, nitric acid, hydrogen peroxide, peroxodisulfuric acid, iodine(VII) oxide, peat soils, thiotriazyl perchlorate, sulfonyl chloride, sulfur, uranyl nitrate, and wood pulp extracts.
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 1 600 mg/kg bw. Remarks:14 d old.
- Inhalation: LCLo - mouse - 397 mg/L air (nominal).
- Dermal: LD50 - rabbit (male) - > 20 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. The substance may cause effects on the central nervous system. This may result in narcosis.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking. The substance may have effects on the central nervous system. May cause addiction.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Lepomis macrochirus - > 10 000 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 165 mg/L - 24 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 100 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - 26 000 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
AEROBIC: Diethyl ether has been included in a list of compounds which were not biodegraded in a relatively short time either in screening tests which utilized sewage sludge inocula or soil inocula(1). Many ethers are known to be resistant to biodegradation(1). The 5-day biological oxygen demand measured for diethyl ether in screening tests ranged from 0%(2,3) to approximately 1.1%(2) in studies using the standard dilution technique with sewage inocula and 0% in a screening study using an activated sludge inoculum(4). A lag time of >10 days was observed in the latter study with activated sludge(4). In a study which used the seawater dilution method with a sewage inoculum, 0% theoretical BOD was observed over a 5-day period(3). No change was observed in the biological oxygen demand in tests of a semi-continuous activated sludge biological treatment simulator which tested for the removal of diethyl ether at a concn of 200 to 800 ppm in a domestic sewage feed over a period of 24 hours(5). A biodegradation study of diethyl ether, based on TOC measurements (GC analysis), using an activated sludge seed and an initial diethyl ether concn of 100 mg/L, indicated 2.5% (6.5%) biodegradation over a period of 4 weeks(6).
Bioaccumulative potential
BCF values of 0.9 to 1.4 and <1.7 to 9.1 were measured for carp exposed to 500 and 50 ug/L of diethyl ether over the course of a 6 week incubation period(1). According to a classification scheme(2), these BCFs suggest bioconcentration in aquatic organisms is low.
Mobility in soil
The Koc of diethyl ether is estimated as approximately 73(SRC), using a log Kow of 0.89(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that diethyl ether is expected to have high mobility in soil(SRC). A vapor-phase partition coefficient of 15.49 was measured for diethyl ether at 30 deg C in the silt and clay size fraction of a calcareous soil (1.2% organic carbon w/w) from Southern Nevada at 52% relative humidity(4).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1155 (For reference only, please check.)
IMDG: UN1155 (For reference only, please check.)
IATA: UN1155 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: DIETHYL ETHER (ETHYL ETHER) (For reference only, please check.)
IMDG: DIETHYL ETHER (ETHYL ETHER) (For reference only, please check.)
IATA: DIETHYL ETHER (ETHYL ETHER) (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Use of alcoholic beverages enhances the harmful effect.Check for peroxides prior to distillation; eliminate if found.