Dicofol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Dicofol
- CAS： 115-32-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Skin irritation, Category 2
Skin sensitization, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P332+P317 If skin irritation occurs: Get medical help.
P333+P317 If skin irritation or rash occurs: Get medical help.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Dicofol
- Common names and synonyms: Dicofol
- CAS number: 115-32-2
- EC number: 204-082-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Inhalation or ingestion causes nausea, headache, weight loss, convulsions, possible kidney and liver damage. Contact with eyes causes irritation. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Observation. Persons exposed to high levels of organochlorine pesticides by any route should be observed for sensory disturbances, incoordination, speech slurring, mental aberrations, and involuntary motor activity that would warn of imminent convulsions. Solid organochlorine insecticides
SECTION 5: Firefighting measures
Suitable extinguishing media
If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Irritating hydrogen chloride fumes may form in fire. Behavior in Fire: Xylene solvent vapors may travel to source of ignition and flash back. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.
Environmental precautions
Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.
Methods and materials for containment and cleaning up
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from acids. Keep in a well-ventilated room.Store above 40 deg F, away from feed, foodstuffs, or any body of water.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Dicofol or kelthane is a white crystalline, wettable powder dissolved in a liquid carrier, (water). The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Since it is a liquid it can easily penetrate the soil and contaminate groundwater and nearby streams. It can cause illness by inhalation, skin absorption, and/or ingestion. It is used as a pesticide.
-
Colour：
Colorless solid
-
Odour：
Solids have slight characteristic odor
-
Melting point/freezing point：
78.5°C
-
Boiling point or initial boiling point and boiling range：
225°C
-
Flammability：
Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
228.8°C
-
Auto-ignition temperature：
986° F (USCG, 1999)
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
less than 0.1 mg/mL at 72° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = 5.02
-
Vapour pressure：
4.64E-09mmHg at 25°C
-
Density and/or relative density：
1.45
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on burning. Decomposes on contact with acids. This produces toxic and corrosive fumes including hydrogen chloride.
Chemical stability
no data available
Possibility of hazardous reactions
Liquid solvent may be flammable.DICOFOL is an organochlorine bridged diphenyl. Halogenated aliphatic compounds are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Halogenated aliphatics are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. DICOFOL hydrolyzes in alkali. It is slightly corrosive to metals. Contact with steel at elevated temperatures causes formation of toxic gases. (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
Contact with steel at elevated temp causes formation of toxic chlorine & hydrogen chloride gases.
Hazardous decomposition products
Dangerous: when heated to decomposition ... they evolve highly toxic /hydrogen/ chloride fumes. chlorides
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 684-809 mg/kg
- Inhalation: LC50 Rat inhalation >5 mg/L over 4 hrs
- Dermal: LD50 Rabbit percutaneous 2100 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group C Possible Human Carcinogen
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and skin (technical grade). The substance may cause effects on the central nervous system, liver and kidneys.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, weight 1 g); Conditions: freshwater, static, 18 deg C, pH 7.1, hardness 44 mg/L CaCO3; Concentration: 1050 ug/L for 24 hr (95% confidence interval: 889-1241 ug/L) /100% purity technical material
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age 2-26 hr, adult); Conditions: freshwater, static; 80 ug/L for 24 hr (95% confidence interval: 71-90 ug/L); Effect: intoxication, immobilization /formulated product
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Dicofol, present at 100 mg/L, reached 0% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). Dicofol degraded with a half-life of 43 days in a silt loam soil(2). The major metabolites were 1,1-(p-chlorophenyl)-2,2-dichloroethanol, p,p'-DCBP, and 3-hydroxy-4,4'-dichlorobenzophenone(2). Volatile residues were 21-22% of the applied, and unextractable residues were 10-15% of the applied after 12 months(2). In a different study, the aerobic biodegradation half-life of dicofol in soil is expected to range from 259 to 348 days based upon a 300 day open bottle experiment with mixed soil (conducted indoors) and a 300 day open bottle experiment with surface soil (conducted outdoors), respectively(3).
Bioaccumulative potential
BCFs of 8200 and 6100 were measured in carp (Coprinus carpio) exposed for a 60 day incubation period at concns of 1.0 and 0.1 ug/L of dicofol, respectively(1). The BCF of dicofol was measured as 15,000, 18,900, 9,500 and 14,500 in fathead minnow at dicofol concns of 12.38, 1.15, 14.95 and 1.33 ppb, respectively(2). Dicofol residues accumulated in bluegill sunfish with BCFs of 6,600, 17,000, and 10,000 in fillet, viscera, and whole fish, respectively, during 28 days of exposure(3). The estimated elimination half-life was 33 days(3). BCFs in fish were reported as 8050-13,500 based on whole body weight(4). According to a classification scheme(5), these BCF values suggest the potential for bioconcentration in aquatic organisms is very high. In crop areas, the highest mean concns of dicofol measured in the biotic matrices were 1.4 ppm for small mammals (FL), 3.9 ppm for terrestrial invertebrates (CA), and 3.8 ppm for reptiles/amphibians (FL)(3). In non-crop areas, highest mean concns were 0.3 ppm for small mammals (NY), 0.76 ppm for terrestrial invertebrates (FL), 0.38 ppm for reptiles/amphibians (FL), 0.9 ppm for birds (FL), and 0.26 ppm for fish (FL)(3).
Mobility in soil
The Koc for dicofol is 8,383 in sand, 8,073 in sandy loam, 5,868 in silty loam, and 5,917 in clay loam(1). Other reported Koc values for dicofol are 7,207 in sand (0.2% organic matter, pH 6.5), 6,945 in sandy loam (1.6% organic matter, pH 5.8), 5,017 in silty loam (2.4% organic matter, pH 7.1), and 5,086 in clay loam (2.8% organic matter, pH 7.0)(2). Dicofol shows moderate to low mobility in batch equilibrium and column leaching studies, with little potential to leach to groundwater(3). In batch equilibrium studies, mobility of dicofol was moderate in sand (Koc of 5,868), and clay loam (Koc of 5,917) soil slurries(3). According to a classification scheme(4), these Koc values suggest that dicofol is expected to be immobile in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The appearance and physical properties of technical products can differ from those of the pure substance.Carrier solvents used in commercial formulations may change physical and toxicological properties.