DL-bornan-2-one SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： DL-bornan-2-one
- CAS： 21368-68-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable solids, Category 2
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H228 Flammable solid
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P370+P378 In case of fire: Use ... to extinguish.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: DL-bornan-2-one
- Common names and synonyms: DL-bornan-2-one
- CAS number: 21368-68-3
- EC number: 244-350-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Artificial respiration may be needed. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Excerpt from ERG Guide 133 [Flammable Solids]: Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution. (ERG, 2016)
Within 5 to 90 minutes after swallowing, the following may be noted: nausea and vomiting; feeling of warmth; headache; confusion, vertigo, excitement, restlessness, delirium, and hallucinations; increased muscular excitability, tremors, and jerky movements; epileptiform convulsions, followed by depression (convulsions sometimes occur early in the syndrome and may be severe, but they do not have the grave prognosis of strychnine convulsions); coma; central nervous depression may at times be the primary clinical response; death results from respiratory failure or from status epilepticus; slow convalescence (days or weeks), often with persistent gastric distress. (USCG, 1999)
SYMPTOMS: Ingestion of this compound may cause nausea, vomiting, vertigo, mental confusion, delirium, convulsions, coma, respiratory failure or death. It may also cause a burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, severe irritation and possible destruction to the tissues of the mucous membranes, upper respiratory tract, eyes and skin. Other symptoms may include congestion and edematous changes in the gastrointestinal tract, kidneys and brain. Ingestion may result in burning in the mouth and throat, epigastric pain, thirst, feeling of tension, dizziness, irrational behavior, unconsciousness, rigidity, rapid pulse, slow respiration, twitching of the facial muscles and muscular spasms. Other symptoms may include flickering, darkening or veiling of vision, noises in the ears and weakness. Exposure to this compound may also result in a feeling of warmth, depression of the central nervous system, difficult breathing, a characteristic breath odor and anuria. Colic may also be a symptom of exposure. Other symptoms may include eye irritation, sore throat, excitement, fever, bluish lips, pale face, loss of sense of smell and agitation. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of carbon monoxide and carbon dioxide. It is harmful if swallowed, inhaled or absorbed through the skin. It can be absorbed through mucous membranes. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
Treatment of camphor intoxication is primarily supportive with a focus on airway management and seizure control. No antidotes are available. Activated charcoal should be administered for gastrointestinal decontamination, although its efficacy is doubtful. Due to prominent CNS effects, the induction of emesis is contraindicated. If liquid camphor is ingested, a nasogastric tube can be used to aspirate gastric contents before instillation of activated charcoal. Alcohols and oil solutions should be avoided because they have been reported to enhance absorption of camphor. Although not readily available, lipid hemodialysis and resin hemoperfusion have been reported to lower blood camphor concentrations in severely poisoned patients. Benzodiazepines such as lorazepam or diazepam are indicated for symptoms of CNS hyperactivity, such as agitation, tremors, and seizures. Phenobarbital can be used for recurrent or prolonged seizures.
SECTION 5: Firefighting measures
Suitable extinguishing media
To fight fire, use foam, carbon dioxide, dry chemical
Specific hazards arising from the chemical
Excerpt from ERG Guide 133 [Flammable Solids]: Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare-burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished. (ERG, 2016)
Behavior in Fire: The solid often evaporates without first melting. (USCG, 1999)
This chemical is flammable. (NTP, 1992)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.
Methods and materials for containment and cleaning up
Methods and materials for containment and cleaning up: sweep up and shovel. Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulation... Keep in suitable, closed containers for disposal...
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants, strong reducing agents, chlorinated solvents and food and feedstuffs. Well closed. Ventilation along the floor.Conditions for safe storage, including any incompatibilities: keep container tightly closed in a dry and well-ventilated place.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | DL-bornan-2-one |
|---|---|
| CAS No. | 21368-68-3 |
|
Recommended Exposure Limit: 10 Hour Time-Weighted Average: 2 mg/cu m. |
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Camphor is a colorless or white colored crystalline powder with a strong mothball-like odor. About the same density as water. Emits flammable vapors above 150°F. Used to make moth proofings, pharmaceuticals, and flavorings.
-
Colour：
Colorless or white crystals, granules, or crystalline masses; or as colorless to white, translucent, tough masses
-
Odour：
Fragrant and penetrating odor
-
Melting point/freezing point：
175°C
-
Boiling point or initial boiling point and boiling range：
204°C
-
Flammability：
Combustible Solid
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 0.6% by volume; Upper flammable limit: 3.5% by volume
-
Flash point：
64°C
-
Auto-ignition temperature：
870.8° F (USCG, 1999)
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Insoluble (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
no data available
-
Vapour pressure：
0.225mmHg at 25°C
-
Density and/or relative density：
0.992
-
Relative vapour density：
5.24 (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on burning. This produces toxic gases and irritating fumes. Reacts violently with strong oxidants, strong reducing agents and chlorinated solvents. This generates fire and explosion hazard.
Chemical stability
no data available
Possibility of hazardous reactions
Evolves flammable and explosive vapors when heated.Dust explosion possible if in powder or granular form, mixed with air.Naphthalene, CAMPHOR, glycerol, or turpentine will react violently with chromic anhydride [Haz. Chem. Data 1967 p. 68].
Conditions to avoid
no data available
Incompatible materials
Reacts violently with ...strong reducing agents and chlorinated solvents, causing fire and explosion hazard.
Hazardous decomposition products
The substance decomposes on burning producing toxic gases and irritating fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 1310 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4; Not classifiable as a human carcinogen. Camphor, synthetic
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Pimephales promelas (Fathead minnow); Conditions: static bioassay; Concentration: 145 mg/L for 1 hr; 112 mg/L/24 hr; 111 mg/L/48 hr; 110 mg/L/72 hr; 110 mg/L/96 hr
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Camphor, at an influent concentration of 4.08 mg/L, was degraded to below detection limits (not specified) during a 20 hour aeration period in an aerobic activated sludge system(1). Camphor did not concentrate in the activated sludge solids. However, the loss of camphor in this process cannot be definitely attributed to biodegradation since there may have been loss due to volatilization(1). Monoterpine ketones were more resistant to biodegradation in aerated lagoon samples than monoterpine hydrocarbons or alcohols(2). The concentration of camphor actually increased in some of the samples which suggests that camphor was being produced in the lagoon. Camphor was on the list of very difficult to biodegrade compounds in a study of organic chemicals found in effluents(3). Camphor, present at 100 mg/L, reached 94% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test which classified the compound as readily biodegradable(4).
Bioaccumulative potential
An estimated BCF of 17 was calculated in fish for camphor(SRC), using a measured log Kow of 2.38(1) and a regression-derived equation(2). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of camphor can be estimated to be 117(SRC). According to a classification scheme(2), this estimated Koc value suggests that camphor is expected to have high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/