Dioxathion SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Dioxathion
- CAS： 78-34-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 3, Dermal
Acute toxicity - Category 2, Inhalation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H311 Toxic in contact with skin
H330 Fatal if inhaled
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
P391 Collect spillage.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Dioxathion
- Common names and synonyms: Dioxathion
- CAS number: 78-34-2
- EC number: 201-107-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .
Most important symptoms/effects, acute and delayed
Very toxic. Probable oral lethal dose for humans is 50-500 mg/kg or between 1 teaspoonful and 1 oz. for a 70 kg (150 lb.) person. It is a cholinesterase inhibitor. Death is primarily due to respiratory arrest arising from failure of the respiratory center, paralysis of respiratory muscles, intense bronchoconstriction, or all three. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
4. 4= very toxic: probable oral lethal dose (human) 50-500 mg/kg, between 1 teaspoon & 1 oz for 70 kg person (150 lb).
When applied dermally to cattle, dioxathion was absorbed into blood rapidly & peak level of radioactivity was reached in 3 hr; whereas, in orally treated animals, it occurred in 12 hr. blood radioactivity persisted @ least 1 wk after application. radioactivity pattern of urine followed that of blood...
SECTION 5: Firefighting measures
Suitable extinguishing media
Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog or foam. (EPA, 1998)
Specific hazards arising from the chemical
Shock can shatter container, releasing contents. (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, it emits highly toxic fumes of oxides of nitrogen, phosphorus, and sulfur. Avoid alkali materials and heat. It is unstable to iron or tin surfaces and when mixed with certain carriers. (EPA, 1998)
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.
Environmental precautions
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs. Dry. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.STORAGE: ...MUST BE STORED IN ITS SEALED ORIGINAL CONTAINERS, IN WELL-AIRED, FRESH & DRY STOREHOUSES OR IN SHADED & POSSIBLY WELL-AIRED PLACES. IT IS RECOMMENDED THAT THE PRODUCT'S TEMP...NOT EXCEED 25-30 DEG C, & KEEP...AWAY FROM SOURCES OF HEAT, FREE FLAMES OR SPARK-GENERATING EQUIPMENT. CONTAINERS MUST BE STACKED IN SUCH A WAY AS TO PERMIT FREE CIRCULATION OF AIR...AT BOTTOM & INSIDE OF PILES. STORAGE AREAS MUST BE LOCATED AT SUITABLE DISTANCE FROM INHABITED BUILDINGS, ANIMAL SHELTERS, & FOOD STORES; MOREOVER, THEY MUST BE INACCESSIBLE TO UNAUTHORIZED PERSONS, CHILDREN, & DOMESTIC ANIMALS. DIMETHOATE
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.1 mg/m3, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Dioxathion is a tan liquid (technical grade is brown). Used for the control of insects and mites on grapes, citrus, walnuts, ornamentals, apples, pears, and quince. Also used as a spray or dip for the control of ticks, lice, hornfly, and sheep ked on cattle, goats, sheep, and hogs. (EPA, 1998)
-
Colour：
TAN LIQUID
-
Odour：
no data available
-
Melting point/freezing point：
-20°C
-
Boiling point or initial boiling point and boiling range：
60 - 68°C at 0.5 mm Hg
-
Flammability：
Noncombustible Liquid
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
no data available
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
117 CENTIPOISES @ 25 DEG C
-
Solubility：
less than 0.1 mg/mL at 68° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
3
-
Vapour pressure：
17.8 mm Hg at 77° F (NTP, 1992)
-
Density and/or relative density：
1.257(26/4°C)
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes above 135°C . This produces toxic fumes including phosphorus oxides and sulfur oxides. Attacks iron and tin surfaces. Hydrolyzed by alkalis.
Chemical stability
Stable in water at neutral ph, but hydrolysed by alkali or on heating. unstable to iron or tin surfaces or when mixed with certain carriers.
Possibility of hazardous reactions
NON-FLAMMABLEDIOXATHION is heat sensitive. This chemical may react with iron or tin surfaces. It may be hydrolyzed by strong acids or alkalis. (NTP, 1992). Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Conditions to avoid
no data available
Incompatible materials
Alkalis, iron or tin surfaces, heat.
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mongrel dog oral approx 10-40 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4; Not classifiable as a human carcinogen.
Reproductive toxicity
no data available
STOT-single exposure
The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. Exposure at high levels could cause death. Medical observation is indicated.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Micropterus salmoides (largemouth bass) 22 ug/kg/96 hr at 18 deg C, wt 1.3 g (95% confidence limit 20-25 ug/l). Static bioassay without aeration, pH 7.2-7.5, water hardness 40-50 mg/l as calcium carbonate and alkalinity of 30-35 mg/l. /Technical material, 100%, tested in hard water, 272 ppm CaCO3
- Toxicity to daphnia and other aquatic invertebrates: EC50 Daphnia magna 0.35 ug/l/48 hr at 2 deg C, first instar (95% confidence limit 0.25-0.49 ug/L). Static bioassay without aeration, pH 7.2-7.5, water hardness 40-50 mg/l as calcium carbonate and alkalinity of 30-35 mg/l. /Technical material, 100%
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
No biodegradation was observed when dioxathion was anaerobically incubated for 25 hr with a bovine rumen inoculum(1). No aerobic biodegradability studies were located.
Bioaccumulative potential
The log octanol/water partition coefficient for dioxathion is estimated to be 2.99(1) from which one estimates a BCF of 110 using a recommended regression equation(2). Therefore dioxathion might be expected to bioconcentrate moderately in fish and aquatic organisms.
Mobility in soil
The log octanol/water partition coefficient for dioxathion is estimated to be 2.99(1) from which one estimates a Koc of 1000 using a recommended regression equation(2), indicating moderately strong adsorptivity to soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2784 (For reference only, please check.)
IMDG: UN2784 (For reference only, please check.)
IATA: UN2784 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Depending on the degree of exposure, periodic medical examination is suggested.The symptoms of acute intoxication do not become manifest until 30 minutes to 2 hours.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.