Chlorotoluron SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Chlorotoluron
- CAS： 15545-48-9
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Carcinogenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H351 Suspected of causing cancer
H410 Very toxic to aquatic life with long lasting effects
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Chlorotoluron
- Common names and synonyms: Chlorotoluron
- CAS number: 15545-48-9
- EC number: 239-592-2
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth.
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
1. wash contaminated skin with soap & water. 2. flush contaminated eyes with copious amounts of fresh water for 15 minutes. 3. ingestions of small amounts (less than 10 mg/kg body weight) occurring less than an hour before treatment, are probably best treated by: a. syrup of ipecac, followed by 1-2 glasses of water. dose for adults & children over 12 years: 30 ml. dose for children under 12 years: 15 ml. b. activated charcoal: /prc: 30 g activated charcoal in 3-4 oz water (children), 100 g in 8-10 oz water (adult)/...after vomiting stops. c. sodium or magnesium sulfate, 0.25 g/kg in tap water, as a cathartic. pesticides of low or moderate toxicity
SECTION 5: Firefighting measures
Suitable extinguishing media
Use water spray, foam, dry powder, carbon dioxide.
Specific hazards arising from the chemical
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Special protective actions for fire-fighters
Use water spray, foam, dry powder, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. Separated from strong bases, strong acids and food and feedstuffs.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
COLOURLESS CRYSTALS OR WHITE POWDER.
-
Colour：
COLORLESS CRYSTALS
-
Odour：
ODORLESS
-
Melting point/freezing point：
147-148°C
-
Boiling point or initial boiling point and boiling range：
367.8°C at 760 mmHg
-
Flammability：
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
176.2°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
IT IS SOLUBLE IN MOST ORGANIC SOLVENTS
-
Partition coefficient n-octanol/water：
Log Kow = 2.41
-
Vapour pressure：
1.33E-05mmHg at 25°C
-
Density and/or relative density：
1.218 g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
On combustion, forms toxic fumes. Reacts with strong acids and strong bases.
Chemical stability
Stable under normal conditions in neutral media. Hydrolyzed by strong acids and alkalis.
Possibility of hazardous reactions
On combustion, forms toxic fumes. Reacts with strong acids and strong bases.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral greater than 10000 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
Tumours have been detected in experimental animals but may not be relevant to humans. See Notes.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
Degradation of chlortoluron proceeds through the cleavage of the C-N bond as demonstrated using both soil and microbial culture studies(1). Chlortoluron had a half-life in soil of 4-6 weeks(2). The only metabolite identified in this study was monomethyl chlortoluron(2). A half-life of between 6-18 weeks was reported for chlortoluron(3). In biometer experiments, half-lives of 93 days and 40 days were measured for chlortoluron in a silty sand and silty loam soil, respectively(4). However, the disappearance of this compound in an outdoor lysimeter experiment was slower in silty loam (49 days, fallow land; 38 days, barley field) than in silty sand(52 days, fallow land; 14 days, barley field)(4). The main metabolite of chlortoluron degradation was N-dimethylated chlortoluron(4). Chlortoluron, applied as either a suspendible concentrate or wettable powder, had a calculated half-life of 96 days for both conditions in one soil (pH 5.1; organic carbon 4.1%; silt 16%; water holding capacity 27%); a second soil (pH 7.0; organic carbon 1.6%; silt 11% water holding capacity 16.6%) had calculated half-lives of 82 and 84 days for a suspendible concentrate and wettable powder, respectively(5).
Bioaccumulative potential
An estimated BCF value of 40 was calculated for chlortoluron(SRC), using an experimental log Kow of 2.41(1,SRC) and a recommended regression-derived equation(2). According to a classification scheme, this BCF value suggests that bioconcentration in aquatic organisms is moderate, not high(3). Winter wheat grown in soil containing 4.7 mg chlortoluron/kg dry soil had bioconcentration factors of 21 and 22 for root material and for shoots, respectively (bioconcentration factor is the concentration of 14C from the chlortoluron in the plant versus the soil)(4).
Mobility in soil
An average organic matter-water distribution of 60 was measured for seven soils (organic matter range 1.09-5.92%; pH range 5.9-7.5)(1). Seventeen soils from Australia had a range of organic matter-water distribution values for this compound from 25-85, giving Koc values ranging from 1-3467 (organic matter range 0.19-6.62; pH range 4.8-8.4)(2). Leaching was studied following field application of chlortoluron to a sandy soil; after 10 cm of rain had fallen, >2 mg/kg, 1 mg/kg, 0.5 mg/kg, and a trace remained in the 0-2.5, 2.5-5, 5-7.5, and 7.5-10 cm depth, respectively(2). Chlortoluron has measured Koc values ranging from 146-346 for eight Czechoslovakian soils (mean=228), with higher values corresponding to soils with a greater content of organic matter(3). Koc values of 271 and 419 were measured for a loamy sand and a mucky peat soil, respectively, at 25 deg C(4). According to a recommended classification scheme(5), these estimated Koc values suggest that chlortoluron has moderate mobility in soil(SRC). Adsorption of chlortoluron corresponds to an L-isotherm indicating that as the solution concentration increases, there is a decrease in site availability(6). Chlortoluron, applied at a rate of 2.0 kg/ha to sandy soil monoliths containers, had a measured Koc of 160 and 113 in the A and B horizons, respectively(7). The addition of liquid manure, increasing the organic carbon content, resulted in reduced mobility(7).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Tumors of kidney and liver were observed at high dose levels in mice.The substance is combustible but no flash point is available in literature.