Chloromethane SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Chloromethane
- CAS： 74-87-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Gases under pressure: Liquefied gas
Flammable gases, Category 1A, Flammable gas
Carcinogenicity, Category 2
Specific target organ toxicity – repeated exposure, Category 2
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H220 Extremely flammable gas
H351 Suspected of causing cancer
H373 May cause damage to organs through prolonged or repeated exposure
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P381 In case of leakage, eliminate all ignition sources.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P403 Store in a well-ventilated place.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Chloromethane
- Common names and synonyms: Chloromethane
- CAS number: 74-87-3
- EC number: 200-817-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention .
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
Inhalation causes nausea, vomiting, weakness, headache, emotional disturbances; high concentrations cause mental confusion, eye disturbances, muscular tremors, cyanosis, convulsions. Contact of liquid with skin may cause frostbite. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Flush eyes with water, and hospitalize. Treat with oxygen against shock, and, if indicated administer stimulants. Treat burns of skin in the usual way.
SECTION 5: Firefighting measures
Suitable extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Toxic and irritating gases are generated in fires. Behavior in Fire: Containers may explode (USCG, 1999)
Special protective actions for fire-fighters
Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out. In other cases extinguish with water spray. In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. NEVER direct water jet on liquid.
Environmental precautions
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. NEVER direct water jet on liquid.
Methods and materials for containment and cleaning up
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas; Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains; Methods and materials for containment and cleaning up: Clean up promptly by sweeping or vacuum.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Ventilation along the floor.Keep container tightly closed in a dry and well-ventilated place. Contents under pressure. Moisture sensitive. Storage class (TRGS 510): Gases
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 50 ppm as TWA; 100 ppm as STEL; (skin); A4 (not classifiable as a human carcinogen).MAK: 100 mg/m3, 50 ppm; peak limitation category: II(2); skin absorption (H); carcinogen category: 3B; pregnancy risk group: B
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles, face shield or eye protection in combination with breathing protection.
Cold-insulating gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Methyl chloride is a colorless gas with a faint sweet odor. Shipped as a liquid under its vapor pressure. A leak may either be liquid or vapor. Contact with the liquid may cause frostbite by evaporative cooling. Easily ignited. Vapors heavier than air. Can asphyxiate by the displacement of air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. Used to make other chemicals and as a herbicide.
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Colour：
Colorless compressed gas or liquid
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Odour：
Faint sweet ethereal odor
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Melting point/freezing point：
-91°C(lit.)
-
Boiling point or initial boiling point and boiling range：
?24.2°C(lit.)
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Flammability：
Flammable Gas
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Lower and upper explosion limit/flammability limit：
Lower flammable limit: 8.1% by volume; Upper flammable limit: 17.4% by volume
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Flash point：
24°C(lit.)
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Auto-ignition temperature：
1169°F
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Decomposition temperature：
no data available
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pH：
no data available
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Kinematic viscosity：
0.00027 Pa.s at 20 deg C (liquid, 0.5 MPa)
-
Solubility：
Slightly soluble (NTP, 1992)
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Partition coefficient n-octanol/water：
log Kow = 0.91
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Vapour pressure：
760 mm Hg at -11° F ; 3672 mm Hg at 68° F (NTP, 1992)
-
Density and/or relative density：
0.915g/mLat 25°C(lit.)
-
Relative vapour density：
1.74 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
NIOSH considers methyl chloride to be a potential occupational carcinogen.
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride and phosgene. Reacts violently with powdered aluminium, powdered zinc, aluminium trichloride and ethylene. This generates fire and explosion hazard. Attacks many metals in the presence of moisture.
Chemical stability
Chemical stability: Stable under recommended storage conditions.
Possibility of hazardous reactions
Flammable gas. Very dangerous fire hazard when exposed to heat, flame or powerful oxidizers. ... May ignite on contact with aluminum chloride or powdered aluminum.The gas is heavier than air and may travel along the ground; distant ignition possible. The gas is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. See Notes.METHYL CHLORIDE can react vigorously with oxidizing agents. May react explosively with sodium, potassium, sodium-potassium alloy, magnesium, zinc. Reacts with aluminum powder in the presence of catalytic amounts of aluminum chloride to form pyrophoric trimethylaluminum. When heated to decomposition, it emits highly toxic fumes of chlorine [Bretherick, 5th ed., 1995, p. 176].
Conditions to avoid
no data available
Incompatible materials
Incompatible materials: Strong oxidizing agents, Iron
Hazardous decomposition products
In contact with moisture undergoes slow decomposition to hydrochloric acid and methanol.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 1800 mg/kg
- Inhalation: LC50 Mouse inhalation 6300 mg/cu m/7 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
The Human Health Assessment Group in EPA's Office of Health and Environmental Assessment has evaluated methyl chloride for carcinogenicity. According to their analysis, the weight-of-evidence for methyl chloride is group C, which is based on limited evidence in animals. No data are available for humans. As a group C chemical, methyl chloride is considered possibly carcinogenic to humans.
Reproductive toxicity
No studies were located concerning developmental or reproductive effects of methyl chloride in humans. Several inhalation studies have demonstrated that methyl chloride causes reproductive effects in animals, with effects such as testicular lesions, disrupted spermatogenesis, and decreased sperm production in male rats. Delayed fetal development was noted in rats exposed to the same concentration of methyl chloride that resulted in maternal toxicity.
STOT-single exposure
The liquid may cause frostbite. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause liver, cardiovascular system and kidney damage. Exposure could cause unconsciousness. Medical observation is indicated. The effects may be delayed.
STOT-repeated exposure
The substance may have effects on the central nervous system. This may result in effects measured using behavioural tests. Animal tests show that this substance possibly causes toxic effects upon human reproduction.
Aspiration hazard
A harmful concentration of this gas in the air will be reached very quickly on loss of containment.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (/Bluegill)/; Conditions: static bioassay in fresh water at 23 deg C, mild aeration applied after 24 hr; Concentration: 550 ppm for 96 hr
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Methyl chloride, present at 3.79-19.2 mg/L, reached 1% of its theoretical BOD in 4 weeks using an activated sludge inoculum concentration of 1 drop/L in the Japanese MITI test(1). Using OECD Guideline 301D (Ready Biodegradability: Closed Bottle Test) with an activated sludge inoculum, methyl chloride (at 3 mg/L) reached 77% degradation after 28 days of incubation(2). Direct measurements of methyl chloride degradation in coastal seawater from Nova Scotia indicated that loss of methyl chloride was due to microbial activity(3). Strains of bacteria isolated from terrestrial, freshwater, estuarine and marine environments have been shown to be capable of biodegrading methyl chloride(2,4). Methyl chloride was biodegraded in a soil microcosm(5).
Bioaccumulative potential
An estimated BCF of 3 was calculated for methyl chloride in fish(SRC), using a log Kow of 0.91(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc for methyl chloride can be estimated to be 13(SRC). According to a classification scheme(2), this estimated Koc value suggests that methyl chloride is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1063 (For reference only, please check.)
IMDG: UN1063 (For reference only, please check.)
IATA: UN1063 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: METHYL CHLORIDE (REFRIGERANT GAS R 40) (For reference only, please check.)
IMDG: METHYL CHLORIDE (REFRIGERANT GAS R 40) (For reference only, please check.)
IATA: METHYL CHLORIDE (REFRIGERANT GAS R 40) (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 2.1 (For reference only, please check.)
IMDG: 2.1 (For reference only, please check.)
IATA: 2.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: (For reference only, please check.)
IMDG: (For reference only, please check.)
IATA: (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Following intoxication patient should be observed carefully for 48 hours.Check oxygen content before entering the area.