Chlorfenvinphos SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Chlorfenvinphos
- CAS： 470-90-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 3, Dermal
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H311 Toxic in contact with skin
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Chlorfenvinphos
- Common names and synonyms: Chlorfenvinphos
- CAS number: 470-90-6
- EC number: 207-432-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. See Notes.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .
Most important symptoms/effects, acute and delayed
Acute: cholinesterase inhibitor which affects central nervous system. Severe illness or death possible. Convulsions or coma and death. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Airway protection. Insure that a clear airway exists. Intubate the patients and aspirate the secretions with a large-bore suction device if necessary. Administer oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. Improve tissue oxygenation as much as possible before administering atropine, so as to minimize the risk of ventricular fibrillation. In severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. Organophosphate pesticides
SECTION 5: Firefighting measures
Suitable extinguishing media
FIRE EXTINGUISHING MEDIA: Alcohol-resistant foam, dry powder, carbon dioxide.
Specific hazards arising from the chemical
Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) This material may burn but does not ignite readily. Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Avoid iron, steel, and brass. Stable when stored in glass or polyethylene lined containers. Avoid alkaline aqueous solutions. (EPA, 1998)
Special protective actions for fire-fighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Do NOT wash away into sewer. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Do NOT wash away into sewer. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs. Well closed. Store in glass-lined or polyethylene-lined containers.IT IS STABLE WHEN STORED IN GLASS OR POLYETHYLENE-LINED CONTAINERS...
SECTION 8: Exposure controls/personal protection
Control parameters
TLV BEI issued
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Chlorfenvinfos is an amber-colored liquid with a mild chemical odor. Used for control of ticks, flies, lice, and mites on cattle and for blowfly, lice, ked, and itchmite on sheep. Controls fleas and mites on dogs; not used on cats. Applied on organic wastes and breeding places of fly larvae. Also used as a foliage insecticide for potatoes, rice, maize, and sugar cane. Used to control soil insects. (EPA, 1998)
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Colour：
Colorless liquid
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Odour：
Mild odor
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Melting point/freezing point：
-23 to -19°C
-
Boiling point or initial boiling point and boiling range：
396.5°C at 760 mmHg
-
Flammability：
Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
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Flash point：
>100°C
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Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
Miscible with most common organic solvents, e.g. acetone, ethanol, kerosene, xylene, propylene glycol, dichloromethane, hexane.
-
Partition coefficient n-octanol/water：
log Kow = 3.81
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Vapour pressure：
3.9E-06mmHg at 25°C
-
Density and/or relative density：
1.373g/cm3
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Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating and on burning. This produces toxic and corrosive fumes of hydrogen chloride (see ICSC 0163) and phosphorus oxides. Attacks tin, brass, iron and steel.
Chemical stability
Slowly hydrolyzed by water or acid, 50% decomp occurs at 38 deg c in greater than 700 hr at ph 1.1, greater than 400 hr at ph 9.1, but unstable in alkali--at 20 deg c 50% loss occurs in 1.28 hr at ph 13.
Possibility of hazardous reactions
NonflammableOrganophosphates, such as CHLORFENVINFOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Conditions to avoid
no data available
Incompatible materials
Incompatible with alkaline materials.
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of hydrogen chloride and POx /phosphorus oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 117-200 mg/kg
- Inhalation: LC50 Rat inhalation 0.05 mg/l air/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. Exposure could cause unconsciousness and death. The effects may be delayed. See Notes. Medical observation is indicated.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: The persistence half-lives for chlorofenvinphos ranged from about 14 days to >150 days in soil(1-8). The initial half-live of chlorofenvinphos in soils varied from 2 wks to more than 23 wks depending on the soil type, the formulation, and the dosage level(1). Chlorofenvinphos is more persistent in peat and least persistent in sandy loam and brick earth; the initial half-life in peat was >16 wks, >12 wks in loam, and >2 wks in sandy loam and brick earth(1). In another study, chlorofenvinphos degraded slowly on peaty soil whereas on sandy soils persistence was much shorter(2). When applied to the surface, the half-life on peat soil was >150 days(2). On sandy loam soil, it was somewhat <30 days(2). On fine sandy soil, half-life dropped to <4 days(2). When granular formulations were applied to sandy loam soil, chlorofenvinphos half-life was 10-12 wk(2). Depth of incorporation of chlorofenvinphos did not affect the residue rate of decline in soil; and about 73% of a granular application, incorporated to a depth of 15 cm, dissipated within 23 wk(2). Trace residues were detected in the soil as long as 4 yr post application(2). In one test using sterilized soil and sand, 95% of initial chlorofenvinphos remained after 45 days of incubation, while in nonsterile soil, 70-98% was degraded suggesting a biological route of disappearance(3). In laboratory studies, the disappearance rate of chlorofenvinphos was more than 15 times faster in nonsterile soil as compared to sterilized soil(4). Using a sandy loam soil and an organic soil, more than 24 weeks of incubation were required to reach 50% degradation of chlorofenvinphos when the soils were sterilized(5); in nonsterilized soils, only one week of incubation or less was needed to reach 50% degradation(5).
Bioaccumulative potential
An estimated BCF of 28 was calculated for chlorofenvinphos(SRC), using a log Kow of 3.81(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). A BCF of 255 has been reported for Mediterranean mussels (Mytilus galloprovincialis)(4). A BCF of 200 has been reported for earthworms(5,6).
Mobility in soil
A Koc of 295 for chlorofenvinphos was measured in silt loam soil containing 3.53% organic matter(1). According to a suggested classification scheme(2), this Koc value suggests that chlorofenvinphos has medium mobility in soil(SRC). Experimental Kd sorption coefficients of 10.6 to 256.0 have been determined for various kaolinite and bentonite clays(3) indicating that strong adsorption to clay particles is possible(SRC). Over a 90 day observation period during a field study in a sandy loam soil (organic carbon content of 0.32%), surface applied chlorofenvinphos did not leach below a 15 cm depth(4); in addition, no lateral soil movement was observed(4), which suggests that chlorofenvinphos has limited mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3017 (For reference only, please check.)
IMDG: UN3017 (For reference only, please check.)
IATA: UN3017 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC, FLAMMABLE, flash point not less than 23 °C (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC, FLAMMABLE, flash point not less than 23 °C (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC, FLAMMABLE, flash point not less than 23 °C (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Depending on the degree of exposure, periodic medical examination is suggested.The symptoms of acute intoxication do not become manifest until 30 minutes to 6-12 hours.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.