Carbendazim SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Carbendazim
- CAS： 10605-21-7
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Germ cell mutagenicity, Category 1B
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H340 May cause genetic defects
H410 Very toxic to aquatic life with long lasting effects
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Carbendazim
- Common names and synonyms: Carbendazim
- CAS number: 10605-21-7
- EC number: 234-232-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Rest.
Most important symptoms/effects, acute and delayed
ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of NOx. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention.
SECTION 5: Firefighting measures
Suitable extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Specific hazards arising from the chemical
Literature sources indicate that this chemical is probably nonflammable. (NTP, 1992)
Special protective actions for fire-fighters
Use water spray, powder.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures. Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from bases and food and feedstuffs.Keep container tightly closed in a dry and well-ventilated place.
SECTION 8: Exposure controls/personal protection
Control parameters
MAK: (inhalable fraction): 10 mg/m3; peak limitation category: II(4); pregnancy risk group: B; germ cell mutagen group: 5
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles.
Protective gloves.
Avoid inhalation of dust and mist.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
PHYSICAL DESCRIPTION: Light gray or beige powder. (NTP, 1992)
-
Colour：
White powder
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Odour：
Odorless /Technical/
-
Melting point/freezing point：
302-307°C
-
Boiling point or initial boiling point and boiling range：
409°C
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Flammability：
Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
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Flash point：
11°C
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Auto-ignition temperature：
no data available
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Decomposition temperature：
302-307°C
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pH：
no data available
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Kinematic viscosity：
no data available
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Solubility：
less than 1 mg/mL at 70° F (NTP, 1992)
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Partition coefficient n-octanol/water：
log Kow = 1.52
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Vapour pressure：
less than 0.000000075 mm Hg at 68° F ; <0.001 mm Hg at 257° F (NTP, 1992)
-
Density and/or relative density：
1.421g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes slowly on contact with bases.
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
CARBENDAZIM is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Conditions to avoid
no data available
Incompatible materials
Incompatible materials: Strong oxidizing agents
Hazardous decomposition products
Decomposes at 300 deg C.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral (in sesame oil) >15,000 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group C Possible Human Carcinogen
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
Animal tests show that this substance possibly causes toxicity to human reproduction or development.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: /Oncorhynchus mykiss/ (Rainbow trout); Concentration: 2.4 mg/L for 96 hr /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea); Concentration: 0.27 mg/L for 96 hr /Conditions of bioassay not specified
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Carbendazim, present at 100 mg/L, reached 0% of its Theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(1). Carbendazim, present at 10.0 ug/mL, was degraded 100% in 5 days in soil previously treated with the fungicide and degraded only 45% in 21 days in uncontaminated soil; mixed bacterial cultures were used(2). Carbendazim was degraded 5% in sterile sand after 14 days, 45% in non-history soil after 14 days, 97% in 2% pretreated soil after 9 days, and 100% in 100% pretreated soil after 7 days(2). Approximately two-thirds of the various fungal isolates capable of degrading carbendazim were identified as Alternaria alternata(3). Based on these data, carbendazim is expected to biodegrade slowly in soil under normal environmental conditions; however, degradation will be enhanced in pretreated soils(SRC).
Bioaccumulative potential
BCFs of <1.5-3.5 and 0.6-1.1 were measured using carp (Cyprinus carpio) exposed to 2 and 20 ug/L, respectively, carbendazim over a 6-week period(1). Carbendazim was not bioconcentrated in perch (Perca fluviatilis) and carp exposed to food pellets containing a mixture of 13 pesticides(2). According to a classification scheme(3), these BCF values suggest bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of carbendazim was reported as 2805 in Hungarian agricultural soil (0.68% organic carbon, 21.8% silt, 15.4% clay, 62.8% sand, pH 6.1)(1). Carbendazim Koc values were reported as 200-250 in uncharacterized soils(2), 122.3-672.7 in European soils(3-4) and 960-2700 in Vietnamese soils(5). According to a classification scheme(6), the Koc range 122.3-2805(1-5) suggests that carbendazim is expected to have high mobility in some soils with decreasing mobility as the amount of clay and organic carbon content increases; pH will have a lesser effect on mobility(5). Carbendazim had Kd values of 1-3 in surface bed sediment from the River Calder, England(7).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
If the substance is formulated with solvents also consult the ICSCs of these materials.Carrier solvents used in commercial formulations may change physical and toxicological properties.