Captan SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Captan
- CAS： 133-06-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Serious eye damage, Category 1
Skin sensitization, Category 1
Acute toxicity - Category 3, Inhalation
Carcinogenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H318 Causes serious eye damage
H317 May cause an allergic skin reaction
H331 Toxic if inhaled
H351 Suspected of causing cancer
H400 Very toxic to aquatic life
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Captan
- Common names and synonyms: Captan
- CAS number: 133-06-2
- EC number: 205-087-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Seek medical attention if you feel unwell.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention.
Rinse mouth. Seek medical attention if you feel unwell.
Most important symptoms/effects, acute and delayed
Vapor irritates eyes. Ingestion causes depression, lachrymation, labored respiration, diarrhea. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Remove patient from contact with the material. Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Dithiocarbamates and Related Compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Irritating and toxic gases are produced in a fire; they may include sulfur dioxide, hydrogen chloride, phosgene, and oxides of nitrogen. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, foam, powder, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Store in an area without drain or sewer access.Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 5 mg/m3, as TWA; (SEN); A3 (confirmed animal carcinogen with unknown relevance to humans)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles or face shield.
Protective gloves. Protective clothing.
Use ventilation (not if powder).
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Captan is a white solid dissolved in a liquid carrier. It is a water emulsifiable liquid. It can cause illness by inhalation, skin absorption and/or ingestion. The primary hazard of this material is that it poses a threat to the environment. In case of release immediate steps should be taken to limit its spread to the environment. Since it is a liquid it can easily penetrate the soil to contaminate groundwater. It is used as a fungicide.
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Colour：
White to cream powder
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Odour：
Odorless [Note: Commercial product has a pungent odor]
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Melting point/freezing point：
178°C
-
Boiling point or initial boiling point and boiling range：
314.2°Cat 760 mmHg
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Flammability：
Combustible Solid; may be dissolved in flammable liquids.
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Lower and upper explosion limit/flammability limit：
no data available
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Flash point：
143.8°C
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Auto-ignition temperature：
no data available
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Decomposition temperature：
no data available
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pH：
no data available
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Kinematic viscosity：
no data available
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Solubility：
less than 1 mg/mL at 68° F (NTP, 1992)
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Partition coefficient n-octanol/water：
log Kow = 2.80
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Vapour pressure：
0.000474mmHg at 25°C
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Density and/or relative density：
1.74
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Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
NIOSH considers captan to be a potential occupational carcinogen.
Decomposes on heating. This produces toxic fumes including sulfur oxides, nitrogen oxides, hydrogen chloride and phosgene.
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
Captan may burn, but does not ignite readily.CAPTAN decomposes at or near the melting point. This chemical is incompatible with strong alkaline and oxidizing materials, sulfur and (sulfur + moisture). (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Incompatible materials: Strong bases
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions - Carbon oxides, nitrogen oxides (NOx), sulfur oxides, hydrogen chloride gas.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 9000 mg/kg
- Inhalation: LC50 Swiss-Webster mouse (male) inhalation 4.5 mg/L/2 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Classification of carcinogenicity: 1) evidence in humans: no adequate data; 2) evidence in animals: limited evidence. Overall summary evaluation of carcinogenic risk to humans is Group 3: The agent is not classifiable as to its carcinogenicity to humans. From table
Reproductive toxicity
No information is available on the reproductive or developmental effects of captan in humans. Evidence on the reproductive and developmental effects of captan in animals is conflicting. In one study where animals were orally exposed, captan was fetotoxic in high-dosed rabbits, a slight reduction in fetal weight was observed in high-dosed rats, and increased resorptions were observed in high-dosed hamsters. Some abnormalities were observed in another study. Other studies have reported no effects.
STOT-single exposure
The substance is irritating to the eyes and skin.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Oncorhynchus mykiss (Rainbow Trout) weight 1 g; Conditions: freshwater, static, 12 deg C, pH 7.4, hardness 44 mg/L CaCO3; Concentration: 76.4 ug/L for 24 hr (95% confidence interval: 69.5-83.9 ug/L) /90% purity technical material
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea); Concentration: 7.06-9.96 ppm for 48 hr /Conditions of bioassay not specified in source examined
- Toxicity to algae: EC50; Species: Anabaena flosaquae (Blue-Green Algae); Conditions: freshwater, static; Concentration: 1200 ug/L for 96 hr (95% confidence limit: 830-1600 ug/L); Effect: population, abundance /99.8% purity
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: (14)C-Labeled captan, present at 50 ppm, was degraded 25% in 8 weeks using a Mexico-Putnam silt loam representative of claypan soils in north Missouri. Crop residues slightly increased degradation(1). A half-life of 2.5 days in soil has been reported in an Italian study, details were not provided(2). Carbonyl-radio-labeled captan, applied to a sandy loam, was degraded 99% after 7 days, 95% of the radio-label was found as CO2 after 322 days(3). Trichloromethyl-radio-labeled captan had a half-life in sandy loam soil of <1 day; 46% of the radio-label was present as CO2 after 1 day and 19.4% was found as parent compound(3). Half-lives of less than one day were reported for captan in two separate aerobic water/sediment systems(3). Captan was degraded 100% in 3 hours from an initial concentration of 50 ug/L in an activated sludge test(4). However, captan, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(5) which may be due to toxicity to microorganisms(SRC).
Bioaccumulative potential
A measured BCF of 126 was reported for captan in bluegill sunfish (Lepomis macrochirus) in a 28 day study(1). A BAF of 113 (wholefish) was determined for captan in a 28-day study using bluegill sunfish(2). After a 14-day depuration period, concentrations declined by 95%(2). According to a classification scheme(3), these BCF values suggest that bioconcentration in aquatic organisms is moderate(SRC).
Mobility in soil
Koc values of 33, 67, 115, 100-600(1), and 200(2) have been reported for captan. According to a classification scheme(3), these Koc values suggest that captan is expected to generally have high to moderate mobility in soil(SRC). A measured organic matter partition coefficient for captan in soil with 3.53% organic matter is 115(4). In field studies at six different sites, however, captan was shown to have slight to no mobility(5). One study predicted that captan would leach <10 cm in a loam soil at 25 deg C under annual rainfall of 150 cm(6). Turf thatch has been shown to increase sorption by a factor of 10(7).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3077 (For reference only, please check.)
IMDG: UN3077 (For reference only, please check.)
IATA: UN3077 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.