Bromacil SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Bromacil
- CAS： 314-40-9
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Bromacil
- Common names and synonyms: Bromacil
- CAS number: 314-40-9
- EC number: 206-245-1
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin, upper respiratory system Target Organs: Eyes, skin, respiratory system, thyroid (NIOSH, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
Skin decontamination: Skin contamination should he treated promptly by washing with soap and water. Contamination of the eyes should be treated immediately by prolonged flushing of the eyes with large amounts of clean water. If dermal or ocular irritation persists, medical attention should be, obtained without delay. Herbicides
SECTION 5: Firefighting measures
Suitable extinguishing media
Bromacil may be ignited by heat or open flame. ... Use dry chemical, carbon dioxide, water spray, or foam extinguishers. ... From a secure, explosion-proof location, use water spray to coll exposed containers. ...
Specific hazards arising from the chemical
Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.
Methods and materials for containment and cleaning up
Remove all ignition sources. Absorb liquid containing Bromacil in vermiculite, dry sand, earth, or similar material. Collect powdered material in the most convenient and safe manner adn deposit in sealed containers. Ventilate area of spill or leak after clean-up is complete. ...
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep in a well-ventilated room. Separated from strong oxidants and strong acids.Do not contaminate water, other pesticides, fertilizer, food or feed in storage. Store in original container. Keep tightly closed in a dry, cool and wellventilated place. Keep out of the reach of children. DuPont Hyvar X Herbicide
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 10 mg/m3, as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Bromacil is a colorless to white odorless crystalline solid. Used as an herbicide. Commercially available as a wettable powder or in liquid formulations. (NIOSH, 2016)
-
Colour：
White crystalline solid
-
Odour：
Odorless
-
Melting point/freezing point：
157-160°C
-
Boiling point or initial boiling point and boiling range：
411°C
-
Flammability：
Noncombustible Solid, but may be dissolved in flammable liquids.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
no data available
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
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pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
0.08 % at 77° F (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
log Kow = 2.11
-
Vapour pressure：
0.0008 mm Hg at 212° F (NIOSH, 2016)
-
Density and/or relative density：
1.55
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes including hydrogen bromide and nitrogen oxides. Decomposes on contact with acids or oxidants.
Chemical stability
Stable to 0 deg F, but water-soluble formulations become less soluble with exposed to air.
Possibility of hazardous reactions
Active ingredient and dry formulations are non-flammable; the liquid formulation (HYVAR-XL) is a combustible mixture which should be kept away from heat and open flame.BROMACIL is incompatible with the following: Strong acids (decomposes slowly), oxidizers, heat, sparks, open flames (NIOSH, 2016).
Conditions to avoid
no data available
Incompatible materials
Strong acids (decomposes slowly), oxidizers, heat, sparks, open flames.
Hazardous decomposition products
Decomposes slowly in strong acids.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat male oral 5200 mg/kg
- Inhalation: LC50 Rat inhalation >4.8 mg/L air/4 hr
- Dermal: LD50 Rabbit percutaneous >5000 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group C Possible Human Carcinogen
Reproductive toxicity
no data available
STOT-single exposure
The substance is mildly irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
no data available
Aspiration hazard
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill sunfish); Concentration: 71 ppm for 48 hr /Conditions of bioassay not specified in source examined
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr; Conditions: freshwater, static; Concentration: 121000 ug/L for 48 hr (95% confidence interval: 111000-148000 ug/L); Effect: intoxication, immobilization /96.6% purity
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae); Conditions: freshwater, static; Concentration: 6.8 ug/L for 5 days (95% confidence interval: 5.9-7.8 ug/L); Effect: population abundance /96.5% purity
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: The microbial degradation of bromacil in aerobic soil is slow with a half-life of 275 days in silty clay loam soil incubated for up to 12 months. Carbon dioxide was the major degradate with 5-bromo-6-methyluracil, 5-bromo-3-(alpha-hydroxymethylpropyl)-6-methyluracil, 5-bromo-3-sec-butyl-6-hydroxymethyluracil, 5-bromo-3-(2-hydroxy-1-methylpropyl)-6-methyluracil and 3-sec-butyl-6-methyluracil found as minor metabolites(1). Bromacil was degraded within 4 to 6 months when single applications were made to soil; however, when two applications were used, bromacil persisted in the top 75 mm of soil for nearly a year(2). The mineralization half-life of (14)C-labeled bromacil, incubated in loamy sand and mucky peat soils, was estimated to range from 5,429 to 46,200 days(3). Bromacil estimated half-life is 12-46 days in two New Zealand soils; Motupiko silt loam (pH 5.7, 24% sand, 57% silt, 19% clay, 2.4% organic content) Waikiwi silt loam (pH 5.5, 7% sand, 69% silt, 24% clay, 3.9% organic content)(4).
Bioaccumulative potential
The bioconcentration of bromacil in bluegill sunfish (Lepomis macrochirus) was studied over a 28-day period using flow-through conditions(1). Bluegill sunfish exposed to 10.6 ppm bromacil had BCF values for muscle, viscera, carcass, and whole fish of 49, 72, 22, and 26.5, respectively(1). At 1.0 ppm, maximum BCF values were 4.6, 8.3, 2.2, and 2.8 for muscle, viscera, carcass, and whole fish, respectively(1). Depuration was rapid, with >96% of the accumulated residues eliminated from the fish tissues by day 3 of the depuration period. A BCF of 3.2 was measured in fathead minnow(2). A log BCF of 0.35242 in bluegill sunfish exposed for 28 days has also been reported(3), corresponding to a BCF of 2.20(SRC). According to a classification scheme(4), these BCF values suggest that bioconcentration in aquatic organisms is low. [
Mobility in soil
Bromacil is very mobile in sand, sandy loam, clay loam and silt loam soils; aged bromacil residues are very mobile in silt loam soils(1). Extensive data exists as evidence that bromacil leaches to ground water as a result of normal agricultural use(1). An average Koc value of 23 was determined from experimental values determined in 8 soils and 4 sediments(2). Koc values of 25 to 50 for for Israeli soils(3), 55 to 126(4), 46 to 93 for 7 sandy Florida soils(5), and 76 to 129 for a mucky peat and a loamy sand Oregon soils incubated at temperatures of 4 and 25 deg C(6) have been reported. Koc values in sand (FL), sandy loam (CA), clay loam (MD), and silt loam (DE) were 12, 33, 2.3, and 14, respectively(7). According to a classification scheme(8), these Koc values suggest that bromacil is expected to have very high to moderate mobility in soil. In soil column leaching studies, bromacil readily leached from loess and sandy soils, but was retained in organic-rich soils(6). As the pH increased from 3 to 12, less adsorption of bromacil to Ca-montmorillonite was measured(4). In 7 sandy soils, a rainfall of 20-23 cm displaced over 96% of applied bromacil(5). Koc values were slightly higher at lower temperatures(6). Maximum bromacil concentrations of 1.25 ppm were detected in groundwater (depths of 4.5-6 meters) three months after the herbicide was applied to a surface of Lakeland, FL sandy soil bearing scrub vegetation of small oaks and poor grasses(9). The pKa of bromacil is 9.30(10), indicating that this compound will exist partially in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(11). Desorption of bromacil from Cuban soils were reported as 51.98 and 67.00% from a red ferralitic soil and a brown plastic soil, respectively; the specific adsorption constants are 2.89 and 23.9 ug/g, respectively(12). Adsorption coefficients 1.79 and 4.59 for Motupiko topsoil (1-10 cm) and subsoil (40-50 cm), respectively, and 1.57 for Waikiwi topsoil (1-10 cm) have been reported for two Wakefield, Nelson, New Zealand soils. Soil characteristics are as follows: Motupiko silt loam (pH 5.7, 24% sand, 57% silt, 19% clay, 2.4% organic content) Waikiwi silt loam (pH 5.5, 7% sand, 69% silt, 24% clay, 3.9% organic content)(13).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Carrier solvents used in commercial formulations may change physical and toxicological properties.