Biphenyl SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Biphenyl
- CAS： 92-52-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Biphenyl
- Common names and synonyms: Biphenyl
- CAS number: 92-52-4
- EC number: 202-163-5
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Rinse mouth. Refer for medical attention .
Most important symptoms/effects, acute and delayed
CALL FOR MEDICAL AID. VAPOR, MIST OR DUST: Irritating to eyes, nose, throat and skin. Flush affected area with plenty of water. IF IN EYES, hold eyelids open and flush with plenty of water. SOLID OR LIQUID: Irritating to skin and eyes, nose and throat. Remove contaminated clothing and shoes. Flush affected areas with plenty water. IF IN EYES, hold eyelids open and flush with plenty of water. If swallowed, do not induce vomiting. Harmful if inhaled or swallowed. Causes irritation to eyes, skin and mucous membrane and upper respiratory tract. Causes central nervous system depression, paralysis and convulsion in animals. May cause headache, diffuse gastrointestinal pain, nausea, indigestion, numbness and aching of limbs, and general fatigue. Liver function test may show abnormalities. Chronic exposure is mostly characterized by central nervous system symptoms, fatigue, headache, tremor, insomnia, sensory impairment, and mood changes. Such symptoms are rare however. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Exposure treatment. Inhalation: Call for medical aid. Remove the victim to fresh air. If not breathing give artificial respiration. If breathing is difficult give oxygen. Ingestion: Do not induce vomiting. Skin: Wash with soap and copious amounts of water. Eyes: Flush with copious amounts of water for at least 15 min.
SECTION 5: Firefighting measures
Suitable extinguishing media
Carbon dioxide, dry chemical, water spray, mist, fog.
Specific hazards arising from the chemical
Combustible. Emits toxic fumes under fire conditions. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, foam, powder, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Environmental considerations: Air spill: Apply water spray or mist to knock down vapors.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Prevent build-up of electrostatic charges (e.g., by grounding). Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs and oxidants. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Materials... toxic as stored or which can decompose into toxic components... should be stored in a cool... ventilated place, out of... sun, away from fire hazard... /and/ be periodically inspected. ...Incompatible materials should be isolated...
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.2 ppm as TWA.MAK: skin absorption (H); carcinogen category: 3B
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection if powder.
Protective gloves.
Avoid inhalation of dust and mist. Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Solid. Flakes.
-
Colour：
White.
-
Odour：
Pleasant, peculiar odor
-
Melting point/freezing point：
69.45°C.
-
Boiling point or initial boiling point and boiling range：
255.25 °C. Atm. press.:760 mm Hg. Remarks:Reported boiling point is 255.25 ± 0.05 °C.
-
Flammability：
Combustible Solid
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 0.6% by volume (at 232 deg F, 111 deg C); Upper flammable limit: 5.8% by volume (at 311 deg F,155 deg C)
-
Flash point：
113 °C.;115 °C.
-
Auto-ignition temperature：
566 °C. Atm. press.:101.3 kPa. Remarks:Measurements determined at ambient atmospheric pressure, but exact barometric pressure is not reported.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 0.95. Temperature:100.0°C.;dynamic viscosity (in mPa s) = 0.57. Temperature:150.0°C.;dynamic viscosity (in mPa s) = 0.38. Temperature:200.0.
-
Solubility：
Insoluble in water
-
Partition coefficient n-octanol/water：
log Pow = 4.008. Temperature:25 °C. Remarks:SD +/- 0.022, pH not reported.
-
Vapour pressure：
0.001 kPa. Temperature:25 °C. Remarks:+/- 0.03.
-
Density and/or relative density：
0.97 g/cm3. Temperature:100 °C.;1.17 g/cm3. Temperature:24.5 °C.
-
Relative vapour density：
5.31 (USCG, 1999) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Reacts with oxidants.
Chemical stability
Very stable in acidic & alkaline media.
Possibility of hazardous reactions
Slight when exposed to heat or flame; can react with oxidizing materials.Dust explosion possible if in powder or granular form, mixed with air.BIPHENYL is incompatible with oxidizers. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Reacts with oxidants causing fire and explosion hazard.
Hazardous decomposition products
This substance decomposes on heating producing toxic gases, acrid smokes and fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 2 400 mg/kg bw. Remarks:One to five days with most deaths occurring within two days.
- Inhalation: LC50 Mouse inhalation 0.275 mg/L/4 hr
- Dermal: LD50 - rabbit (male/female) - > 5 010 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Reproductive toxicity
No information is available on the reproductive or developmental effects of biphenyl in humans. Limited data indicate that biphenyl does not cause teratogenic effects (birth defects) in animals. Some evidence (not significant) of fetotoxicity has been observed in rats exposed to high levels of biphenyl via gavage (experimentally placing the chemical in the stomach).
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
The substance may have effects on the liver and nervous system. This may result in impaired functions.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - 3 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 0.36 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 2.5 mg/L - 96 h.
- Toxicity to microorganisms: NOEC - Colpidium colpoda - >= 6.3 mg/L - 18 h.
Persistence and degradability
Several organisms have been found that can grow on diphenyl and use it as the sole carbon source.
Bioaccumulative potential
Bioconcentration factors for biphenyl in golden orfe (Leuciscus idus melanotus) and the amphipod Rhepoxynius abronius, have been measured as 280(1) and 4,500(2). Measured BCF values for rainbow trout (Salmo gairdneri) were reported as 437(3) and 1,318(4). According to a classification scheme(5), these BCF values indicate that bioconcentration in aquatic organisms is high to very high(SRC). Bivalve molluscs, Mercenaria mercenaria L., exposed to waste crankcase oil containing biphenyl for 2 days, did not significantly depurate biphenyl over a 45 day period in clean water(6).
Mobility in soil
In three soils, the log Koc was determined to be in the range 2.94-3.52 (Koc of 871-3,331)(1). The experimental mean log Koc value in five soils was 3.16 (Koc of 1,445)(3). The log Koc value in humic acids was determined to be 3.27 (Koc of 1,862)(4). According to a recommended classification scheme(2), these log Koc values indicate biphenyl may have low to slight mobility in soil(SRC). A log Koc of 5.09 was measured using soot columns and an SRM-1650 soot standard obtained from NIST(5). A retardation factor (Rf) of 2.1 was measured for biphenyl using soil columns filled with a surface soil (organic carbon = 12.6%, 60.3% sand, 24.0% silt, 15.7% clay, porosity = 0.7)(6). A retardation factor of 2.2-2.3 was measured for biphenyl on columns packed with low carbon aquifer material(7). The sorption of biphenyl on HDTMA clays indicated that sorption occurs via partition interactions with the HDTMA-derived organic phase. The greater the HDTMA content and the larger spacings of high charge HDTMA clays increased biphenyl's sorption(8).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3077 (For reference only, please check.)
IMDG: UN3077 (For reference only, please check.)
IATA: UN3077 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.