4,4'-carbonimidoylbis(N,N-dimethylaniline) monohydrochloride SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 4,4'-carbonimidoylbis(N,N-dimethylaniline) monohydrochloride
- CAS： 2465-27-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 3, Dermal
Carcinogenicity, Category 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H302 Harmful if swallowed
H311 Toxic in contact with skin
H351 Suspected of causing cancer
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 4,4'-carbonimidoylbis(N,N-dimethylaniline) monohydrochloride
- Common names and synonyms: 4,4'-carbonimidoylbis(N,N-dimethylaniline) monohydrochloride
- CAS number: 2465-27-2
- EC number: 219-567-2
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
SYMPTOMS: Exposure to this compound may cause skin and eye irritation. It may also cause skin burns, dermatitis, eye irritation, edema of eyelids, hyperemia, corneal opacity, necrosis, corneal erosion, nausea and vomiting. ACUTE/CHRONIC HAZARDS: This compound is harmful if swallowed, inhaled or absorbed through the skin. It may cause skin and eye irritation. When heated to decomposition, this compound emits toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides and hydrochloride gas. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
no data available
SECTION 5: Firefighting measures
Suitable extinguishing media
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)
Specific hazards arising from the chemical
Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal ... The plastic bag should be sealed immediately ... The sealed bag should be labelled properly ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. Chemical Carcinogens
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
PHYSICAL DESCRIPTION: Yellow flakes or powder. (NTP, 1992)
-
Colour：
Yellow powder
-
Odour：
no data available
-
Melting point/freezing point：
188°C(lit.)
-
Boiling point or initial boiling point and boiling range：
137°C
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
42°C(lit.)
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
less than 1 mg/mL at 64° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
no data available
-
Vapour pressure：
8.31E-07mmHg at 25°C
-
Density and/or relative density：
1.01g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
AURAMINE O is incompatible with strong oxidizing agents. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
The Human Health Assessment Group in EPA's Office of Health and Environmental Assessment has evaluated auramine for carcinogenicity. According to their analysis, the weight-of-evidence for auramine is group B2, which is based on inadequate evidence in humans and sufficient evidence in animals. As a group B2 chemical, auramine is considered probably carcinogenic to humans. Auramine
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
Using an initial concn of 100 mg/L auramine hydrochloride, 0 %BOD was observed after a 2 week period in a biodegradation screening test using 30 mg/L sludge(1). Based on a five-day BOD value of 0.038 g/g determined in an aerobic aqueous screening test utilizing municipal waste activated sludge, a theoretical BOD value of 1.3% can be calculated for auramine hydrochloride(2,SRC).
Bioaccumulative potential
The BCF range for auramine hydrochloride was experimentally determined to be 3.8-16 in a flow-through test using carp, Cyprinus Carpio(1). This BCF value indicates that auramine hydrochloride will not bioconcentrate in fish(SRC).
Mobility in soil
Aromatic amines have been observed to undergo rapid and reversible covalent bonding with humic materials in aqueous solution; the initial bonding reaction is followed by a slower and much less reversible reaction believed to represent the addition of the amine to quinoidal structures followed by oxidation of the product to give an amino-substituted quinone; these processes represent pathways by which aromatic amines may be converted to latent forms in the biosphere(4). In the absence of covalent bonding, one can estimate the adsorption potential based on the Koc value. Based on an experimental water solubility of 10,000 mg/L(2) and a recommended regression-derived equation(1), the Koc value for auramine hydrochloride can be estimated to be 27(SRC). According to a suggested classification scheme(3), this Koc value indicates that auramine hydrochloride will have very high soil mobility. However, using a structure estimation method(5), Koc values of 50,000 and 25,000 can be estimated for auramine hydrochloride and its parent compound, respectively, and these Koc values indicate that auramine hydrochloride will be immobile in soil(3,SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2811 (For reference only, please check.)
IMDG: UN2811 (For reference only, please check.)
IATA: UN2811 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IATA: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/