7,12-dimethylbenz[a]anthracene SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 7,12-dimethylbenz[a]anthracene
- CAS： 57-97-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Carcinogenicity, Category 1B
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H302 Harmful if swallowed
H350 May cause cancer
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 7,12-dimethylbenz[a]anthracene
- Common names and synonyms: 7,12-dimethylbenz[a]anthracene
- CAS number: 57-97-6
- EC number: 200-359-5
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
SYMPTOMS: Symptoms of exposure to this compound include irritation of the skin, eyes and gastrointestinal tract. It may also cause acetonemia. ACUTE/CHRONIC HAZARDS: This compound is harmful by ingestion, inhalation or skin absorption. It is an irritant of the skin, eyes and gastrointestinal tract. When heated to decomposition it emits acrid smoke, irritating fumes and toxic fumes of carbon monoxide and carbon dioxide. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
After iv injection into rats, 7,12-dimethylbenz(a)anthracene was taken up rapidly by the liver, bound to particular fractions, & subsequently transformed into polar metab, which have less affinity for particulate fractions than the parent hydrocarbon, & which were recovered from cellular cytosol. after transfer to cytosol, metabolites were secreted into bile.
SECTION 5: Firefighting measures
Suitable extinguishing media
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Specific hazards arising from the chemical
This chemical is combustible. (NTP, 1992)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Substances in this high-chronic-toxicity category incl heavy metal compd & compd ... classified as strong carcinogens. examples of compd ... considered to be strong carcinogens incl ... 7,12-dimethylbenz(a)anthracene ... all containers ... in this category should have labels that identify the contents & incl warning ... storage areas for substances in this category should have limited access, & special signs should be posted if a special toxicity hazard exists. any area used for storage ... maintained under negative pressure with respect to surrounding areas.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
PHYSICAL DESCRIPTION: Yellow to greenish-yellow crystals or a yellow solid. Odorless. Maximum fluorescence at 440 nm. Bluish-violet fluorescence in UV light. (NTP, 1992)
-
Colour：
PLATES, LEAFLETS FROM ACETONE & ALC, FAINT GREENISH-YELLOW TINGE
-
Odour：
no data available
-
Melting point/freezing point：
217°C(lit.)
-
Boiling point or initial boiling point and boiling range：
191°C(lit.)
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
58°C(lit.)
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
less than 1 mg/mL at 64° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
Log Kow = 5.80
-
Vapour pressure：
no data available
-
Density and/or relative density：
0.9 g/mL at 25°C(lit.)
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
7,12-DIMETHYLBENZ[A]ANTHRACENE is incompatible with strong oxidizing agents (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
Carbon-14 labeled 7,12-dimethylbenz(a)anthracene was introduced into a large marine microcosm typical of shallow marine waters. Within 12 hours after the addition, 20 percent of the degradation products was transferred to the sediments. The rate of Carbon-14 labeled carbon dioxide production resulting from the metabolism of degradation products was initially 0.63 percent per day, then dropped to 0.13 percent per day after 40 days. After 62 days in an enclosed marine ecosystem, 12 percent of the 7,12-dimethylbenz(a)anthracene had been respired to carbon dioxide, and about 18 percent could be extracted from sediments(1). In another study, 7,12-dimethylbenz(a)anthracene was not degraded in 6 days in a standard BOD test using an activated sludge inoculum(2).
Bioaccumulative potential
An estimated BCF of 7,100 was calculated for 7,12-dimethylbenz(a)anthracene(SRC), using an experimental log Kow of 5.80(1,SRC) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF suggests that bioconcentration in aquatic organisms would be very high(SRC). Dimethylbenz(a)anthracene, having a maximum exposure concentration of 0.0006 ppm, was determined to bioconcentrate in the marine species Macoma inquinata at a level of 0.86 ppm after 7 days. This yielded a bioconcentration factor of 1,349(4). Dimethylbenzanthracene bioaccumlation in the presence of 0.2 mg/l humic acid was determined to be 64.2 nmol/g dry wt Daphnia after 6 hours, having a BCF of 968. Dimethylbenzanthracene bioaccumlation in the presence of 2.0 mg/l humic acid was determined to be 55.8 nmol/g dry wt Daphnia after 6 hours, having a BCF of 666(5). This demonstrated that the presence of humic acid did not significantly change the bioavailability of 7,12-dimethylbenz(a)anthracene to Daphnia(5). When deposit feeding clams, Macoma inquinata, were exposed to detritus contaminated with Prudoe Bay Crude Oil, to which an unspecified isomer of dimethylbenzanthracene had been added for 7 days, the log bioconcentration factor from seawater was 3.13. The chemical associated with sediment was not available for uptake(6).
Mobility in soil
7,12-Dimethylbenz(a)anthracene adsorbs very strongly to soils and sediment. The mean Koc value for its adsorption to 13 soils and sediments from the central U.S. was 235,700(1). According to a recommended classification scheme(3), this Koc value suggests that 7,12-dimethylbenz(a)anthracene would be immobile in soil(SRC). While adsorption was strongly correlated to organic carbon content, it was independent of other soil or sediment properties such as pH, cation exchange capacity, clay content or mineralogy(1). Another investigator found that 20-40% of 7,12-dimethylbenz(a)anthracene was sorbed in water and wastewater samples(2).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1993 (For reference only, please check.)
IMDG: UN1993 (For reference only, please check.)
IATA: UN1993 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: FLAMMABLE LIQUID, N.O.S. (For reference only, please check.)
IMDG: FLAMMABLE LIQUID, N.O.S. (For reference only, please check.)
IATA: FLAMMABLE LIQUID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/