Heptan-3-one SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Heptan-3-one
- CAS： 106-35-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 3
Eye irritation, Category 2
Acute toxicity - Category 4, Inhalation
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H226 Flammable liquid and vapour
H319 Causes serious eye irritation
H332 Harmful if inhaled
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Heptan-3-one
- Common names and synonyms: Heptan-3-one
- CAS number: 106-35-4
- EC number: 203-388-1
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Rest. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Short term exposure can cause irritation of eyes, nose, throat and lungs. High concentrations may cause headache, dizziness or unconsciousness. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
INHALATION. Symptoms: Cough. Dizziness. Headache. Sore throat. Unconsciousness. First aid: Fresh air, rest. Refer for medical attention. SKIN: Symptoms: Dry skin. Redness. First aid: Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES: Symptoms: Redness. Pain. First aid: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION: First aid: Rinse mouth. Rest. Refer for medical attention.
SECTION 5: Firefighting measures
Suitable extinguishing media
Fire Extinguishing Agents Not to Be Used: Water. Fire Extinguishing Agents: Dry chemical, alcohol foam, or carbon dioxide. (USCG, 1999)
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire. (USCG, 1999)
Special protective actions for fire-fighters
Use powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable metal containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable metal containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.
Methods and materials for containment and cleaning up
1. remove all ignition sources. 2. ventilate area of spill or leak. 3. for small quantities, absorb on paper towels. evaporate in safe place (such as fume hood). allow ... evaporating vapors to completely clear the hood ductwork. burn the paper in suitable location away from combustible materials.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 46°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof.Prior to working with this chemical you should be trained on its proper handling and storage. Ethyl butyl ketone must be stored to avoid contact with oxidizers such as peroxides, chlorates, perchlorates, permanganates, and nitrates, because violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away form heat. Sources of ignition such as smoking and open flames are prohibited where ethyl butyl ketone is used, handled, or stored in a manner that could create a potential fire or explosion hazard.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 50 ppm as TWA; 75 ppm as STEL.MAK: 47 mg/m3, 10 ppm; peak limitation category: I(2); pregnancy risk group: D.EU-OEL: 95 mg/m3, 20 ppm as TWA
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Ethyl butyl ketone is a colorless odorless liquid with a mild fruity odor. Flash point 140°F.
-
Colour：
Clear liquid
-
Odour：
GREEN ODOR
-
Melting point/freezing point：
360°C(dec.)(lit.)
-
Boiling point or initial boiling point and boiling range：
148°C
-
Flammability：
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 1.4% by volume; Upper flammable limit: 8.8% by volume
-
Flash point：
46°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
0.84 cP at 20 deg C
-
Solubility：
1 % (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
log Kow = 1.73 (est)
-
Vapour pressure：
4.22mmHg at 25°C
-
Density and/or relative density：
0.819
-
Relative vapour density：
3.93 (Air = 1)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
PROBLEM OF FLAMMABILITY SHOULD NOT BE GREAT UNLESS MATERIAL IS HANDLED @ ELEVATED TEMP.ETHYL BUTYL KETONE is reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion. Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. May react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. Irritating vapors and toxic gases may be formed when involved in fire (USCG, 1999).
Conditions to avoid
no data available
Incompatible materials
Forms explosive mixture with air. Violent reaction with strong oxidizers, acetaldehyde, perchloric acid. Attacks some plastics, rubber, and coatings.
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 2760 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. Exposure could cause lowering of consciousness.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: A 3.7 percent theoretical BOD was observed for 3-heptanone (initial concn of 500 ppm) in a Warburg respirometer after 1 day of incubation with activated sludge inocula at 20 deg C(1).
Bioaccumulative potential
An estimated BCF of 6 was calculated in fish for 3-heptanone(SRC), using a water solubility of 4,300 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of 3-heptanone is estimated as 44(SRC), using a water solubility of 4,300 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 3-heptanone is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1224 (For reference only, please check.)
IMDG: UN1224 (For reference only, please check.)
IATA: UN1224 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: KETONES, LIQUID, N.O.S. (For reference only, please check.)
IMDG: KETONES, LIQUID, N.O.S. (For reference only, please check.)
IATA: KETONES, LIQUID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/