2,6-dinitrotoluene SDS

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Dermal

Acute toxicity - Category 3, Inhalation

Germ cell mutagenicity, Category 2

Carcinogenicity, Category 1B

Specific target organ toxicity – repeated exposure, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

Reproductive toxicity, Category 2

H301 Toxic if swallowed

H311 Toxic in contact with skin

H331 Toxic if inhaled

H341 Suspected of causing genetic defects

H350 May cause cancer

H373 May cause damage to organs through prolonged or repeated exposure

H412 Harmful to aquatic life with long lasting effects

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P203 Obtain, read and follow all safety instructions before use.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

P301+P316 IF SWALLOWED: Get emergency medical help immediately.

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P316 Get emergency medical help immediately.

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P318 IF exposed or concerned, get medical advice.

P319 Get medical help if you feel unwell.

P405 Store locked up.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

INHALATION, INGESTION OR SKIN ABSORPTION: Headache, weakness, nausea or dizziness, cyanosis, drowsiness, shortness of breath and collapse. Can burn eyes and skin. (USCG, 1999)

In case of ingestion, induction of emesis is not recommended because of the potential for central nervous system depression. Gastric lavage and administration of activated charcoal may be considered soon after ingestion, provided airways are protected. Dinitrotoluene

Water, carbon dioxide, or dry chemical from protected location.

Special Hazards of Combustion Products: Emits toxic fumes of oxides of nitrogen Behavior in Fire: May explode when exposed to heat or flame. (USCG, 1999)

Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.

Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

1) remove all ignition sources. 2) ventilate area of spill. 3) for small quantities, sweep onto paper or other suitable material & burn in suitable combustion chamber which allows burning in unconfined condition & is equipped with appropriate effluent gas cleaning device. large quantities may be reclaimed ... if ... not practical, dissolve in fuel oil & atomize in suitable combustion chamber equipped with appropriate effluent gas cleaning device. dinitrotoluene

NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Fireproof. Separated from strong bases, food and feedstuffs, oxidants and strong reducing agents. Well closed. Keep in a well-ventilated room.Storage temperture: Ambient

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield.

Protective gloves. Protective clothing.

Use local exhaust or breathing protection.

no data available

NIOSH considers dinitrotoluene to be a potential occupational carcinogen. [50 mg/cu m] Dinitrotoluene

May explode on heating. Decomposes on heating. This produces toxic and corrosive fumes including nitrogen oxides even in the absence of air. Reacts with reducing agents, strong bases and oxidants. This generates explosion hazard.

no data available

CombustibleDust explosion possible if in powder or granular form, mixed with air.2,6-DINITROTOLUENE is sensitive to heat. It may explode when exposed to heat or flame. It can be detonated only by a very strong initiator. This chemical is incompatible with strong oxidizers. It is also incompatible with caustics and metals such as tin and zinc. It may react with reducing agents. It will attack some forms of plastics, rubber and coatings. (NTP, 1992)

no data available

STABILITY: This chemical is stable under normal laboratory conditions. Solutions of this chemical in water, DMSO, 95% ethanol or acetone should be stable for 24 hours under normal lab conditions.REACTIVITY: This compound reacts with oxidizers, caustics, nitric acid, reducing materials and metals, such as zinc or tin. It may react violently in the presence of a base or when heated to the boiling point. It attacks some forms of plastics, rubbers and coatings. (NTP, 1992)

When heated to decomposition it emits toxic fumes of /nitrogen oxides/.

no data available

no data available

no data available

no data available

Evaluation: There is inadequate evidence in humans for the carcinogenicity of ... 2,6-dinitrotoluene. There is sufficient evidence in experimental animals for the carcinogenicity of ... 2,6-dinitrotoluene. Overall evaluation: ... 2,6-Dinitrotoluene /is/ possibly carcinogenic to humans (Group 2B).

no data available

The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

The substance may have effects on the blood. This may result in the formation of methaemoglobin. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

AEROBIC: The biodegradability of 2,6-dinitrotoluene was tested in a static screening test using flasks that contained either 5 or 10 mg/L 2,6-dinitrotoluene, 5 mg/L yeast extract and settled domestic sewage as the inoculum. Subcultures were done every 7 days. The percent biodegradation by the original culture and first, second and third subcultures at an initial 2,6-dinitrotoluene concentration of 10 mg/L was: 57, 49, 35 and 13%, respectively(1). 2,6-Dinitrotoluene at an initial concentration of 10 ug/ml (10 mg/L) did not significantly degrade after 28 days incubation with raw municipal sewage(2). In another study, 2,6-dinitrotoluene inhibited biodegradation of municipal sewage at concentrations above 50 mg/L(3). In the same study, industrial seed degraded 50 mg/L 2,6-dinitrotoluene to 25 mg/L in 2 days, but after 7 days, 2,6-dinitrotoluene concentration remained at 25 mg/L. 2,6-Dinitrotoluene was easy to degrade according to results obtained by the "cultivation method" in which 98-100% and 83-100% degradation occurred in 3 days in river water and coastal sea water in Japan, respectively(7). 2,6-Dinitrotoluene was easily degraded by microorganisms in seawater, although the 2,6-isomer was the least readily degraded than all other dinitrotoluene isomers(4). This is consistent with the observation that the rate of reduction of nitro compound increases with increasing electron withdrawing power of groups in the para position(6). Degradation in river water was generally higher than in seawater(5). No degradation rates were given. The average percent biodegradation in eleven test runs of a pilot activated sludge plant was 57%(8).

An estimated BCF of 11 was calculated for 2,6-dinitrotoluene(SRC), using a log Kow of 2.10(1) and a regression-derived equation(2). The BCF for dinitrotoluene (mixed isomers) has been measured to be low (BCF values of 0.6 to 21.2) in carp (Carprinus carpio)(3). According to a classification scheme(4), these BCF values suggest the potential for bioconcentration in aquatic organisms is low. An experimental log BCF of 2.44 (BCF of 275) (fat basis) was determined for 2,6-dinitrotoluene in the guppy (Poecilia reticulata) in a 3-day static test(5).

The Freundlich adsorption constant (exponent 1/n) for 2,6-dinitrotoluene in a Mississippi sandy loam soil (pH 5.6, organic carbon 0.94%) and a Texas sandy silt loam soil (pH 8.1, organic carbon 3.25%) was 0.014 (0.68) and 0.005 (0.61), respectively(1) which correspond to Koc values of 72 and 19, respectively(SRC). In a loamy sand soil containing an organic matter content of 8.5 g/kg, 2,6-dinitrotoluene had measured Kd adsorption coefficient 0.97 cu cm/g(2) that correspond to a Koc 197(SRC). According to a classification scheme(3), these Koc values indicate that 2,6-dinitrotoluene is expected to have very high to moderate mobility in soil. Field monitoring at a munition factory site in Melbourne Australia found that 2,6-dinitrotoluene migrated large distances in the subsurface soils(4). Leaching of 2,6-dinitrotoluene has been observed in soil column transport studies(5).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN3454 (For reference only, please check.)

IMDG: UN3454 (For reference only, please check.)

IATA: UN3454 (For reference only, please check.)

ADR/RID: DINITROTOLUENES, SOLID (For reference only, please check.)

IMDG: DINITROTOLUENES, SOLID (For reference only, please check.)

IATA: DINITROTOLUENES, SOLID (For reference only, please check.)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

ADR/RID: II (For reference only, please check.)

IMDG: II (For reference only, please check.)

IATA: II (For reference only, please check.)

ADR/RID: No

IMDG: No

IATA: No

no data available

no data available

Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Do NOT take working clothes home.UN number for molten form: UN1600.See ICSC 0465.