2,6-dimethylheptan-4-one SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2,6-dimethylheptan-4-one
- CAS： 108-83-8
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 3
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Warning
H226 Flammable liquid and vapour
H335 May cause respiratory irritation
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2,6-dimethylheptan-4-one
- Common names and synonyms: 2,6-dimethylheptan-4-one
- CAS number: 108-83-8
- EC number: 203-620-1
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Inhalation of vapor causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Vaporirritates eyes. Contact with liquid irritates skin. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
INHALATION. Symptoms: Cough. Dizziness. Headache. Nausea. Sore throat. Vomiting. First aid: Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. SKIN: Symptoms: Redness. Numbness. First aid: Remove contaminated clothes. Rinse and then wash skin with water and soap. EYES: Symptoms: Redness. Pain. First aid: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION: First aid: Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.
SECTION 5: Firefighting measures
Suitable extinguishing media
In case of fire: keep drums, etc., cool by spraying with water. AFFF, alcohol-resistant foam, powder, carbon dioxide.
Specific hazards arising from the chemical
Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. Substance may be transported hot. For hybrid vehicles, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. If molten aluminum is involved, refer to ERG Guide 169. (ERG, 2016)
Special protective actions for fire-fighters
Use AFFF, alcohol-resistant foam, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Ventilate area of spill or leak. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or similar material and deposit in sealed containers. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 49°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants.MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS ... SHOULD BE STORED IN A COOL, WELL VENTILATED PLACE, OUT OF THE DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, AND SHOULD BE PERIODICALLY INSPECTED. IMCOMPATIBLE MATERIALS SHOULD BE ISOLATED.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 25 ppm as TWA
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Liquid.
-
Colour：
Colourless.
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Odour：
Peppermint odor
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Melting point/freezing point：
-45.98°C. Atm. press.:Ca. 101.3 kPa.
-
Boiling point or initial boiling point and boiling range：
168.26°C. Atm. press.:101.3 kPa.
-
Flammability：
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 0.8% by volume @ 200 deg F (93 deg C); Upper flammable limit: 7.1% by volume @ 200 deg F (93 deg C)
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Flash point：
49 °C. Atm. press.:Ca. 101.3 kPa.
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Auto-ignition temperature：
345 °C. Atm. press.:Ca. 101.3 kPa.
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Decomposition temperature：
no data available
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pH：
no data available
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Kinematic viscosity：
dynamic viscosity (in mPa s) = 1.05. Temperature:20°C. Remarks:Referenec: Ullmann's Encyclopedia of Industrial Chemistry,.;dynamic viscosity (in mPa s) = 0.869. Temperature:25.0°C. Remarks:Reference: Kirk-Othmer Encyclopedia of Chemical Technology.
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Solubility：
Slightly soluble (NTP, 1992)
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Partition coefficient n-octanol/water：
log Pow = 3.71. Temperature:25 °C. Remarks:PH not relevant for HPLC method, as the substance is not ionizable.
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Vapour pressure：
0.23 kPa. Temperature:20 °C. Remarks:Reference: Ullmann.;1.7 mm Hg. Temperature:20 °C. Remarks:Reference: Verschueren/Hawley.;2.3 mm Hg. Temperature:30 °C. Remarks:Reference: Verschueren.
-
Density and/or relative density：
0.81 g/ml. Temperature:20 °C.;0.81 g/cm3. Temperature:20 °C.
-
Relative vapour density：
4.9 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Reacts with oxidants. Attacks some forms of plastic.
Chemical stability
no data available
Possibility of hazardous reactions
Flammable liquid when exposed to heat or flame ...DIISOBUTYL KETONE may attack some plastics. It reacts with oxidizers. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Reacts with oxidants. Attacks some forms of plastics.
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - > 2 000 mg/kg bw.
- Inhalation: LC50 - rat - > 14.5 mg/L air (nominal).
- Dermal: LD50 - rat (male/female) - > 2 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. Exposure to high concentrations could cause lowering of consciousness.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis.
Aspiration hazard
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 30 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 37.2 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 46.9 mg/L - 72 h.
- Toxicity to microorganisms: IC50 - aerobic microorganisms - 255 mg/L - 16 h.
Persistence and degradability
AEROBIC: Using standard BOD dilution techniques with acclimated microbial cultures, theoretical BODs of 37.4-46.7% were measured for diisobutyl ketone over 5-day incubation periods(1,2). Diisobutyl ketone had BODs of 4, 39, 57, and 88% of theoretical measured over 5, 10, 15, and 20 day incubation periods, respectively, using standard BOD dilution techniques and a non-acclimated sewage inoculum(3); theoretical BODs of 4, 9, and 18% were measured over 10, 15, and 20 day incubation periods, respectively, using a synthetic salt BOD dilution water and a non-acclimated sewage inoculum(3).
Bioaccumulative potential
An estimated BCF of 7 was calculated in fish for diisobutyl ketone(SRC), using a water solubility of 2,640 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of diisobutyl ketone is estimated as 57(SRC), using a water solubility of 2,640 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that diisobutyl ketone is expected to have high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1157 (For reference only, please check.)
IMDG: UN1157 (For reference only, please check.)
IATA: UN1157 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: DIISOBUTYL KETONE (For reference only, please check.)
IMDG: DIISOBUTYL KETONE (For reference only, please check.)
IATA: DIISOBUTYL KETONE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/