2,6-xylidinium chloride SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2,6-xylidinium chloride
- CAS： 21436-98-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
no data available
GHS label elements, including precautionary statements
- Signal word no data available
no data available
no data available
no data available
no data available
no data available
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2,6-xylidinium chloride
- Common names and synonyms: 2,6-xylidinium chloride
- CAS number: 21436-98-6
- EC number: 244-388-1
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
Immediate First Aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Specific hazards arising from the chemical
no data available
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations. Keep in suitable, closed containers for disposal.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | 2,6-xylidinium chloride |
|---|---|
| CAS No. | 21436-98-6 |
|
Recommended Exposure Limit: 10-hour Time-Weighted Average: 2 ppm (10 mg/cu m). Skin. |
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
no data available
-
Colour：
Yellow liquid
-
Odour：
Characteristic odor
-
Melting point/freezing point：
188°C(lit.)
-
Boiling point or initial boiling point and boiling range：
131°C/2.5mmHg(lit.)
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Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
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Flash point：
57°C(lit.)
-
Auto-ignition temperature：
520 deg C
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Decomposition temperature：
no data available
-
pH：
no data available
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Kinematic viscosity：
1.7 mPa.s (dynamic) at 50 deg C
-
Solubility：
In water, 8240 ppm at 25 deg C
-
Partition coefficient n-octanol/water：
log Kow = 1.84
-
Vapour pressure：
0.13mmHg at 25°C
-
Density and/or relative density：
0.9842 g/cu cm at 20 deg C
-
Relative vapour density：
4.2 (Air = 1)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
This chemical is a combustible liquid. Xylidines
Conditions to avoid
no data available
Incompatible materials
Incompatible materials: Acids, acid chlorides, acid anhydrides, oxidizing agents, chloroformates, halogens.
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 840 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: There is inadequate evidence in humans for the carcinogenicity of 2,6-dimethylaniline. There is sufficient evidence in experimental animals for the carcinogenicity of 2,6-dimethylaniline. Overall evaluation: 2,6-dimethylaniline is possibly carcinogenic to humans (Group 2B).
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: A Warburg respirometer study utilizing an activated sludge seed and 6 hr of incubation resulted in a 2,6-xylidine depletion of 33-37% at a concentration of 20 ppm(1). In a 6 week soil degradation study using (14)C-labelled 2,6-xylidine, 8.4% of applied radioactivity was recovered via CO2 evolution in non-autoclaved soil while 0% CO2 evolution occurred in autoclaved soil(2). In a soil degradation study conducted in glass vessels using Chernozem soil, 2,6-xylidine (at 500 mg/L) was degraded after 3 days of incubation with >90% recovered in transformation products(3). Using OECD Guideline 301F (Ready Biodegradability: Manometric Respirometry Test), 2,6-xylidine (at 100 mg/L) reached 4, 8, 25, 38 and 69% of its theoretical BOD after 7, 13, 36, 42 and 70 days. respectively(4); these results indicated that 2,6-xylidine was not readily biodegradable according to OECD criteria, however, it is biodegradable after extended adaptation(4). In another OECD Guideline 301F study, 2,6-xylidine (at 100 mg/L) showed no bidegradation after 33 day(4). Using OECD Guideline 302B (Inherent biodegradability: Zahn-Wellens/EMPA Test) and an industrial activated sludge seed, 83% of initial 2,6-xylidine was removed from the aqueous test system after 11 days, however, the substance was mainly removed via volatilization(4). 2,6-Xylidine, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(5).
Bioaccumulative potential
An estimated BCF value of 8 was calculated for 2,6-xylidine in fish(SRC), using a log Kow of 1.84(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of 2,6-xylidine can be estimated to be 190(SRC). According to a classification scheme(2), this estimated Koc value suggests that 2,6-xylidine is expected to have moderate mobility in soil. Aromatic amines are expected to bind strongly to humus or organic matter in soils due to the high reactivity of the aromatic amino group(3,4), suggesting that mobility may be lower in some soils(SRC). In a short term soil adsorption study using 14C-labelled 2,6-xylidine, 66% of the applied radioactivity was bound to the soil (3.4% organic matter, 36.6% sand, 28.2% silt, 35.2% clay) after 24 hrs(3).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3272 (For reference only, please check.)
IMDG: UN3272 (For reference only, please check.)
IATA: UN3272 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ESTERS, N.O.S. (For reference only, please check.)
IMDG: ESTERS, N.O.S. (For reference only, please check.)
IATA: ESTERS, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/