2-chlorotoluene SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2-chlorotoluene
- CAS： 95-49-8
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Inhalation
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H332 Harmful if inhaled
H411 Toxic to aquatic life with long lasting effects
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2-chlorotoluene
- Common names and synonyms: 2-chlorotoluene
- CAS number: 95-49-8
- EC number: 202-424-3
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Inhalation of vapor may cause respiratory irrtation. Prolonged and repeated vapor exposures may produce systemic toxic effects. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Applied under occlusive dressing to 2 guinea pigs ... there was ... evidence of skin absorption ...
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide. Chlorotoluenes
Specific hazards arising from the chemical
Special Hazards of Combustion Products: May contain toxic chloride fumes. Behavior in Fire: Container may explode in heat of fire. Vapor may travel to a source of ignition and flashback. Vapor explosion hazard indoors, outdoors or in sewer. Toxic chloride fumes may be produced. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, carbon dioxide, foam, powder. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 43°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 50 ppm as TWA
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Colourless.
-
Odour：
Aromatic odor.
-
Melting point/freezing point：
-35.6 °C.
-
Boiling point or initial boiling point and boiling range：
159.2 °C. Atm. press.:1 013 hPa.
-
Flammability：
Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
43 °C.
-
Auto-ignition temperature：
> 500 °C.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
dynamic viscosity (in mPa s) = 1.022. Temperature:20°C.
-
Solubility：
Insoluble in water
-
Partition coefficient n-octanol/water：
log Pow = 3.185.
-
Vapour pressure：
4.7 hPa. Temperature:25 °C.
-
Density and/or relative density：
1.08. Temperature:20 °C.
-
Relative vapour density：
4.38 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
On combustion, forms toxic and corrosive fumes including hydrogen chloride and phosgene. Reacts with oxidants.
Chemical stability
no data available
Possibility of hazardous reactions
SLIGHT, WHEN EXPOSED TO HEAT OR FLAME. /4-CHLOROTOLUENE/O-CHLOROTOLUENE may be incompatible with strong oxidizing and reducing agents. Also may be incompatible with amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Reacts violently with dimethyl sulfoxide (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
Acids, alkalis, oxidizers, reducing materials, water.
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male) - 3 227 mg/kg bw.
- Inhalation: LC50 - rat (male) - 7 119 ppm.
- Dermal: LD50 - rat (male/female) - > 1 080 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking.
Aspiration hazard
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Oryzias latipes - 7.7 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.7 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 7.8 mg/L - 72 h.
- Toxicity to microorganisms: TT - Pseudomonas putida - 15 mg/L - 16 h.
Persistence and degradability
In the Japanese MITI test, using an initial concn of 100 ppm 2-chlorotoluene, <30% of the theoretical BOD was reached in 14 days using an activated sludge inoculum(1,2). In the modified MITI test, using an initial concentration of 100 ppm 2-chlorotoluene, 0% of the theoretical BOD was reached in 14 days(3). A second order rate constant for the microbial degradation of 2-chlorotoluene in natural water was experimentally determined to be 2.7X10-11 L/organism-hr(4). Microorganisms capable of degrading 2-chlorotolune were isolated from soil samples collected at a landfill site used for the disposal of chlorinated organic wastes(5). A microbial blend of 10 different bacteria and 2 fungi was used to degrade 2-chlorotoluene at a concentration of 200 mg/l; complete biodegradation occurred in 3 days(6).
Bioaccumulative potential
Carp exposed to 2-chlorotoluene at 0.045 and 0.45 mg/L had measured BCF values of 20-112 and 41.6-87.2, respectively(1). An estimated BCF value of 230 was calculated for 2-chlorotoluene(SRC), using a measured log Kow of 3.42(2) and a recommended regression-derived equation(3). According to a recommended classification scheme(4), these BCF values suggest that bioconcentration of 2-chlorotoluene in aquatic organisms may occur(SRC).
Mobility in soil
Measured soil adsorption coefficients (Koc) for 2-chlorotoluene ranged between 170-880, the average value was 370(1). According to a recommended classification scheme(3), these Koc values suggest that 2-chlorotoluene will have low to moderate mobility in soil(2,SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2238 (For reference only, please check.)
IMDG: UN2238 (For reference only, please check.)
IATA: UN2238 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: CHLOROTOLUENES (For reference only, please check.)
IMDG: CHLOROTOLUENES (For reference only, please check.)
IATA: CHLOROTOLUENES (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/