2-(4-chloro-2-methylphenoxy)propionic acid SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2-(4-chloro-2-methylphenoxy)propionic acid
- CAS： 93-65-2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
no data available
GHS label elements, including precautionary statements
- Signal word no data available
no data available
no data available
no data available
no data available
no data available
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2-(4-chloro-2-methylphenoxy)propionic acid
- Common names and synonyms: 2-(4-chloro-2-methylphenoxy)propionic acid
- CAS number: 93-65-2
- EC number: 202-264-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
Bath and shampoo with soap and water to remove chemicals from skin and hair. Obtain medical treatment if irritation persists. Individuals with chronic skin disease or known sensitivity to these herbicides should either avoid using them or take strict precautions to avoid contact (respirator, gloves, etc). FLUSH contaminating chemicals from eyes and copious amounts of clean water for 10-15 minutes. If irritation persists, obtain medical treatment. Chlorophenoxy compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
In case of fire in the surroundings, use appropriate extinguishing media.
Specific hazards arising from the chemical
Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Liquid spillage should be dammed-off and pumped into containers; soak up remainder with absorbent material and dispose of in accordance with local regulations. Mecoprop-P
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store in an area without drain or sewer access. Separated from food and feedstuffs.Do not...store near heat or open flame. Protect from freezing. Salts of mecoprop
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Mecoprop is a colorless crystals. Corrosive to metals. Used as an herbicide.
-
Colour：
Colorless crystals
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Odour：
Odorless
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Melting point/freezing point：
88-90°C
-
Boiling point or initial boiling point and boiling range：
327°C
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Flammability：
Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
no data available
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
In water, 880 mg/L at 25 deg C
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Partition coefficient n-octanol/water：
log Kow = 3.13
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Vapour pressure：
1.6 mPa (1.2X10-5 mm Hg) at 25 deg C
-
Density and/or relative density：
1.35 g/cm3
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Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes including hydrogen chloride. The solution in water is a weak acid. Attacks some forms of coatings and metals in the presence of moisture.
Chemical stability
Stable to heat, and to hydrolysis, reduction, and atmospheric oxidation.
Possibility of hazardous reactions
PURE MECOPROP AS WELL AS COMMERCIAL PRODUCTS ARE NONFLAMMABLE.A phenoxy aryloxyalkanoic acid derivative.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /hydrogen chloride/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 600 mg/kg Technical material
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
There is limited evidence of the carcinogenicity of mecoprop to humans. There is no data for evaluation of the carcinogenicity of mecoprop to animals. Overall evaluation: Group 2B: The agent is possibly carcinogenic to humans. Chlorophenoxy herbicides
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
See Notes.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly on spraying or when dispersed, especially if powdered.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill); Conditions: freshwater, static; Concentration: >92000 ug/L for 96 hr /92.7% purity formulation
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr; Conditions: freshwater, static; Concentration: 100000 ug/L for 48 hr; Effect: intoxicaiton, immobilization />90% purity formulation
- Toxicity to algae: EC50; Species: Scenedesmus subspicatus (Green Algae) 1x10+4 cells/mL; Conditions: freshwater, renewal, 25 deg C; Concentration: 102660 ug/L for 96 hr (95% confidence interval: 97642-108678 ug/L); Effect: decreased population abundance /98% purity
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Mecoprop is decomposed in soil by microbial degradation(1). The estimated half-lives of 14C-ring-labeled mecoprop (2 ppm) in a sandy loam soil at 50% water holding capacity at 20, 10 and 5 deg C was 3, 12, and 20 days, respectively. In dry and flooded soil (25% and 200% of water holding capacity) at 20 deg C, the half-lives increased to 10 and 15 days, respectively. The half-life decreased by 43% when the concentration of mecoprop was decreased by a factor of 10. Comparing the half-lives of mecoprop in surface soil and subsurface soil, the investigators found half-lives of mecoprop in an undisturbed soil column of a coarse sandy soil to be 7 days at 0-33 cm depth, 70 days at 33-66 cm depth and 34 days at 66-99 cm depth. In these experiments when half of the mecoprop had disappeared, 12% of the 14C was recovered as CO2 and when 90% of the mecoprop had disappeared, 50% of the 14C was evolved as CO2. The degradation intermediates were not identified(1). Using UV absorption, HPLC, GC-MS and other techniques to monitor the course of mecoprop biodegradation using enriched mixed culture from a soil sample, found that biodegradation was incomplete (75%) and that 4-chloro-2-methylphenol was an intermediate(2). GC-MS data also suggested that other phenolic compounds with repositioned chloro and methyl groups are formed(2). The half-lives of mecoprop in clay loam, heavy clay loam, and sandy loam soils at 20 deg C and 85% field moisture capacity were 9, 8, and 7 days, respectively(3). An earlier experiment in which the UV absorption was used to monitor the disappearance of mecoprop (50-80 ppm) with an inoculum of Mardin silt loam, Honeoye silt loam and Dunkirk silt loam; 100% degradation, as typified by the loss of the aromatic ring, was not completely obtained in 47, 124, and 205 days, respectively when incubated at 30 deg C and pH 7.2(4). Using undisturbed soil core techniques and different applications of 14C-ring labeled mecoprop, biodegradation studies were performed resulting in 14.2 to 25.07% 14CO2 evolution over the 90 day study period(5). Under aerobic conditions, (S)-mecoprop degrades faster than (R)-mecoprop(6).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for mecoprop(SRC), using a log Kow of 3.20(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The soil distribution coefficient for mecoprop in three Danish agricultural soils were: sandy loam (pH 6.9), 0.12; sandy loam (pH 6.7), 0.20 and coarse sandy soil (pH 6.6), 0.07(1). The corresponding Koc values were 8.4, 13.3, and 5.3, respectively(1). Koc values for mecoprop were also reported as 5 to 43(2). According to a classification scheme(3), these Koc values suggest that mecoprop is expected to have very high mobility in soil. The pKa of mecoprop is 3.78(4), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Leaching experiments were conducted in which mecoprop (2.26 kg/ha) was applied to turfgrass lysimeter (37 cm soil profile) plots (prepared with 3 common northeastern soils and irrigated with 28.5 cm of water over 71 days)(6). Leachate was collected after 30, 52 and 71 days. In all three cases the maximum concentration of mecoprop in leachate was found after 52 days which was 10, 18, and 310 ppb in Hudson silt loam (pH 6.5), Arkport fine sandy loam (pH 6.5), and sand (pH 6.7), respectively(6). The soil partition coefficient of mecoprop to 5 Dutch subsoils (6-7 m below the soil surface) was very low, 0.142 to 0.326 in three soils and zero in the other two soils(7).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2761 (For reference only, please check.)
IMDG: UN2761 (For reference only, please check.)
IATA: UN2761 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOCHLORINE PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IMDG: ORGANOCHLORINE PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IATA: ORGANOCHLORINE PESTICIDE, SOLID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Mecoprop is a chlorophenoxy-herbicide which, as a group, has been classified by IARC (1987) as possibly carcinogenic to humans, but the data on this specific substance are inconclusive.Carrier solvents used in commercial formulations may change physical and toxicological properties.Other CAS number 7085-19-0.