1,5-naphthylene diisocyanate SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 1,5-naphthylene diisocyanate
- CAS： 3173-72-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity – single exposure, Category 3
Respiratory sensitization, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H412 Harmful to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P319 Get medical help if you feel unwell.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 1,5-naphthylene diisocyanate
- Common names and synonyms: 1,5-naphthylene diisocyanate
- CAS number: 3173-72-6
- EC number: 221-641-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Rest. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, nose, throat; respiratory sensitization, cough, pulmonary secretions, chest pain, dyspnea (breathing difficulty); asthma Target Organs: Eyes, respiratory system (NIOSH, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
no data available
SECTION 5: Firefighting measures
Suitable extinguishing media
Excerpt from ERG Guide 155 [Substances - Toxic and/or Corrosive (Flammable / Water-Sensitive)]: Note: Most foams will react with the material and release corrosive/toxic gases. CAUTION: For Acetyl chloride (UN1717), use CO2 or dry chemical only. SMALL FIRE: CO2, dry chemical, dry sand, alcohol-resistant foam. LARGE FIRE: Water spray, fog or alcohol-resistant foam. FOR CHLOROSILANES, DO NOT USE WATER; use AFFF alcohol-resistant medium-expansion foam. Move containers from fire area if you can do it without risk. Use water spray or fog; do not use straight streams. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
Specific hazards arising from the chemical
Excerpt from ERG Guide 155 [Substances - Toxic and/or Corrosive (Flammable / Water-Sensitive)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. (ERG, 2016)
Special protective actions for fire-fighters
Use foam, powder, carbon dioxide. NO water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.
Environmental precautions
Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
See Chemical Dangers. Well closed.
SECTION 8: Exposure controls/personal protection
Control parameters
MAK: carcinogen category: 3B; sensitization of respiratory tract (SA)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles or eye protection in combination with breathing protection if powder.
Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Solid. Crystalline.
-
Colour：
White to yellowish.
-
Odour：
no data available
-
Melting point/freezing point：
127 °C.
-
Boiling point or initial boiling point and boiling range：
167. Atm. press.:7 hPa. Remarks:Pressure is not reported.
-
Flammability：
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
73°C(lit.)
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
In water: soluable
-
Partition coefficient n-octanol/water：
log Pow = 0.91.
-
Vapour pressure：
0 hPa. Temperature:25 °C. Remarks:Calculated.;0.01 hPa. Temperature:79.6 °C.;0.002 hPa. Temperature:67.3 °C.
-
Density and/or relative density：
1.4. Temperature:20 °C.
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes of nitrogen oxides, carbon monoxide, isocyanates and hydrogen cyanide. Reacts with acids, alcohols, amines, bases, strong oxidants, strong reducing agents and water.
Chemical stability
no data available
Possibility of hazardous reactions
Isocyanates and thioisocyanates, such as 1,5-NAPHTHALENE DIISOCYANATE, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].
Conditions to avoid
no data available
Incompatible materials
This compound is incompatible with the following:None reported (NIOSH, 1997)
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 cut-off - rat (female) - >= 5 000 mg/kg bw.
- Inhalation: LC50 - rat (male/female) - 270 mg/m3 air.
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC-3
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
Repeated or prolonged inhalation may cause asthma.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LL0 - Danio rerio (previous name: Brachydanio rerio) - 50 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EL0 - Daphnia magna - >= 100 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 8.744 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - > 10 000 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Reacts violently with fire extinguishing agents such as water (above 50°C).The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.Rest and medical observation are therefore essential.Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.Do NOT take working clothes home.