1,1,1,2-tetrachloroethane SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 1,1,1,2-tetrachloroethane
- CAS： 630-20-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 1, Dermal
Eye irritation, Category 2
Acute toxicity - Category 3, Inhalation
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H302 Harmful if swallowed
H310 Fatal in contact with skin
H319 Causes serious eye irritation
H331 Toxic if inhaled
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 1,1,1,2-tetrachloroethane
- Common names and synonyms: 1,1,1,2-tetrachloroethane
- CAS number: 630-20-6
- EC number: 211-135-1
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Do NOT induce vomiting. Refer for medical attention . Give one or two glasses of water to drink.
Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin; lassitude (weakness, exhaustion), restlessness, irregular respiration, muscle incoordination Target Organs: Eyes, skin, central nervous system, liver (NIOSH, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Halogenated aliphatic hydrocarbons and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide. Apply water from as far a distance as possible. Keep run-off water out of sewers and water sources. Tetrachloroethane
Specific hazards arising from the chemical
Literature sources indicate that this chemical is nonflammable. (NTP, 1992)
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Methods and materials for containment and cleaning up
Evacuate and restrict persons not wearing protective equipment for the area of spill or leak until cleanup is complete. Remove all ignition sources. Ventilate area of spill or leak. Absorb liquids in vermiculite, dry sand,earth, peat, carbon, or a similar material and deposit in sealed containers. ... It may be necessary to contain and dispose of this chemical as a hazardous waste.
SECTION 7: Handling and storage
Precautions for safe handling
NO contact with hot surfaces. NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants and strong bases. Well closed.Store in tightly closed containers in a cool, well-ventilated area away from potassium; sodium; dinitrogen tetraoxide; potassium hydroxide; nitrogen tetraoxide; sodium potassium alloy; 2,4-dinitrophenyl disulfide. Metal containers involving the transfer of 5 gallons or more of this chemical should be grounded and bonded.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | 1,1,1,2-tetrachloroethane |
|---|---|
| CAS No. | 630-20-6 |
|
Handle with caution in the workplace. NIOSH considers ethylene dichloride; hexachloroethane; 1,1,2,2-tetrachloroethane; and 1,1,2-trichloroethane; to be potential occupational carcinogens. Additionally, NIOSH recommends that the other five chloroethane compounds: 1,1-dichloroethane; ethyl chloride; methyl chloroform; pentachloroethane; and 1,1,1,2-tetrachloroethane be treated in the workplace with caution because of their structural similarity to the four chloroethanes shown to be carcinogenic in animals. |
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
PHYSICAL DESCRIPTION: Clear colorless liquid. (NTP, 1992)
-
Colour：
Colorless, heavy liquid
-
Odour：
no data available
-
Melting point/freezing point：
285°C(lit.)
-
Boiling point or initial boiling point and boiling range：
131°C
-
Flammability：
Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
268°C(lit.)
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
1.50X10-3 Pa-sec at 20 deg C
-
Solubility：
less than 1 mg/mL at 68.9° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = 2.93 (est)
-
Vapour pressure：
10 mm Hg at 66.7° F ; 20 mm Hg at 89.8° F (NTP, 1992)
-
Density and/or relative density：
1.598 g/mL at 25°C(lit.)
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic and corrosive gases including hydrogen chloride. Reacts with strong bases and strong oxidants.
Chemical stability
no data available
Possibility of hazardous reactions
It is non combustible.1,1,1,2-TETRACHLOROETHANE is incompatible with strong oxidizing agents and strong bases. It is also incompatible with dinitrogen tetraoxide, 2,4-dinitrophenyl disulfide, potassium, potassium hydroxide, nitrogen tetraoxide, sodium and sodium potassium alloy. It may react with chemically active metals, strong caustics, hot iron, aluminum and zinc in presence of steam. It may also react with mixtures of dinitrogen tetraoxide with halocarbons. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Mixtures of potassium with tetra- and pentachloroethane will often explode spontaneously after a short delay during which a voluminous solid separates out.
Hazardous decomposition products
When in contact with flame, incandescent material or red hot metal surfaces, it decomp to form hydrochloric acid, carbon dioxide, and carbon monoxide.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 670 mg/kg
- Inhalation: LC50 Rat inhalation 2100 ppm/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: No epidemiological data relevant to the carcinogenicity of 1,1,1,2-tetrachloroethane were available. There is limited evidence in experimental animals for the carcinogenicity of 1,1,1,2-tetrachloroethane. Overall evaluation: 1,1,1,2-Tetrachloroethane is not classifiable as to its carcinogenicity to humans (Group 3).
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system.
STOT-repeated exposure
no data available
Aspiration hazard
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, weight 0.32-1.2 g); Conditions: freshwater, static, 21-23 deg C, pH 6.5-7.9, hardness 32-48 mg/L CaCO3, alkalinity 28-34 mg/L CaCO3, conductivity 93-190 umhos/cm, dissolved oxygen 0.3-9.7 mg/L; Concentration: 20 mg/L for 24 hr /> or =80% purity
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea, age <24 hr); Conditions: freshwater, static, 22 deg C, pH 8.0 (7.4-9.4), hardness 173 mg/L CaCO3, dissolved oxygen >60%; Concentration: 27000 ug/L for 24 hr (22000-35000 ug/L) />80% purity
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
Biodegradation data are not available for 1,1,1,2-tetrachloroethane(SRC, 2008); however, biodegradation data for the isomer 1,1,2,2-tetrachloroethane indicate that degradation will be slow under aerobic conditions, but may proceed under anaerobic conditions(1).
Bioaccumulative potential
An estimated BCF of 12 was calculated in fish for 1,1,1,2-tetrachloroethane(SRC), using a water solubility of 1.07X10+3 mg/L at 25 deg C(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The experimentally determined Koc for 1,1,1,2-tetrachloroethane is 399(1). According to a classification scheme(2), this Koc value suggests that 1,1,1,2-tetrachloroethane is expected to have moderate mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2810 (For reference only, please check.)
IMDG: UN2810 (For reference only, please check.)
IATA: UN2810 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TOXIC LIQUID, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: TOXIC LIQUID, ORGANIC, N.O.S. (For reference only, please check.)
IATA: TOXIC LIQUID, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
See ICSC 0332.