N,N-dimethylhydrazine SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： N,N-dimethylhydrazine
- CAS： 57-14-7
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 2
Acute toxicity - Category 3, Oral
Skin corrosion, Sub-category 1B
Acute toxicity - Category 3, Inhalation
Carcinogenicity, Category 1B
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H225 Highly flammable liquid and vapour
H301 Toxic if swallowed
H314 Causes severe skin burns and eye damage
H331 Toxic if inhaled
H350 May cause cancer
H411 Toxic to aquatic life with long lasting effects
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: N,N-dimethylhydrazine
- Common names and synonyms: N,N-dimethylhydrazine
- CAS number: 57-14-7
- EC number: 200-316-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Refer immediately for medical attention.
First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .
Rinse with plenty of water (remove contact lenses if easily possible).
Rinse mouth. Rest. Do NOT induce vomiting. Refer immediately for medical attention.
Most important symptoms/effects, acute and delayed
This compound exhibits high acute toxicity as a result of exposure by all routes. Death or permanent injury may result after very short exposure to small quantities. Chronic exposure may cause pneumonia, liver damage, and kidney damage. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Specific treatment for exposure consists of thorough washing of all exposed skin areas with soap and water, copious irrigation of the eyes, and prompt removal of the patient from the source of exposure. Hydrazines
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.
Specific hazards arising from the chemical
Vapor may explode if ignited in an enclosed area. Vapors may travel to a source of ignition and flashback. Runoff to sewer may create fire or explosion hazard. When it decomposes, 1,1-dimethylhydrazine gives off toxic nitrogen compound fumes. Dissolves, swells, and disintegrates many plastics. Dangerous when exposed to heat, flame, or oxidizers. Hazardous polymerization may not occur. (EPA, 1998)
Special protective actions for fire-fighters
Use powder, alcohol-resistant foam, water in large amounts, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable non-plastic containers. Do NOT absorb in saw-dust or other combustible absorbents. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable non-plastic containers. Do NOT absorb in saw-dust or other combustible absorbents. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Activated carbon, polyurethane foam and polypropylene fibers are the most advantageous agents for cleanup of 1,1-dimethylhydrazine. Also Amberlite XAD resins and Dowex 50WX8 or Amberlite IRA 900 may be used.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents or acids. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Provision to contain effluent from fire extinguishing. Separated from strong oxidants and strong acids. Dry. Well closed. Keep in a well-ventilated room. Do NOT store or transport in containers made from plastic. Store in an area without drain or sewer access.PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.01 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: skin absorption (H); sensitization of skin (SH); carcinogen category: 2
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
1,1-dimethylhydrazine is a clear colorless liquid with an ammonia-like odor. Flash point 0°F. Corrosive to the skin. Less dense than water and soluble in water. Vapors are heavier than air and very toxic by inhalation, attacking the eyes and respiratory system. Prolonged exposure of containers to heat may result in their violent rupturing and rocketing due to decomposition. Generates toxic oxides of nitrogen when burned. Vapors may travel to a source of ignition and a flame can flashback to the source of vapors. Used as a rocket propellant and to make other chemicals.
-
Colour：
CLEAR, COLORLESS LIQUID
-
Odour：
Characteristic ammonia like fishy odor of aliphatic hydrazines
-
Melting point/freezing point：
-57.2°C
-
Boiling point or initial boiling point and boiling range：
62-64°C (753 mmHg)
-
Flammability：
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
-
Lower and upper explosion limit/flammability limit：
Lower 2% by vol; Upper 95% by vol
-
Flash point：
-18°C
-
Auto-ignition temperature：
480° F (NTP, 1992)
-
Decomposition temperature：
no data available
-
pH：
STRONGLY ALKALINE LIQ
-
Kinematic viscosity：
0.492 millipascal second @ 25 deg C
-
Solubility：
Decomposes (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = -1.19 /Estimated/
-
Vapour pressure：
103 mm Hg ( 20 °C)
-
Density and/or relative density：
0.785
-
Relative vapour density：
1.94 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
15 ppm; NIOSH considers 1,1-dimethylhydrazine to be a potential occupational carcinogen.
On combustion, forms toxic fumes including nitrogen oxides. The substance is a strong reducing agent. It reacts violently with oxidants. The substance is a strong base. It reacts violently with acid and is corrosive. Reacts with oxygen. This generates fire and explosion hazard. Attacks plastics.
Chemical stability
Solution stored in dark and cold are relatively stable in absence of oxidants
Possibility of hazardous reactions
It is flammable over a wide range of vapor air concentrations.The vapour is heavier than air and may travel along the ground; distant ignition possible.1,1-DIMETHYLHYDRAZINE is a powerful reducing agent. Ignition can occur on contact with oxidizing agents such hydrogen peroxide and fuming nitric acid [Haz. Chem. Data(1966)]. Also reacts as a base to neutralize acids in exothermic reactions.
Conditions to avoid
no data available
Incompatible materials
Contact of dicyanofurazan, or its N-oxide (dicyanofuroxan), with ... dimethylhydrazine ... is instantaneously explosive.
Hazardous decomposition products
When heated to decomp it emits highly toxic fumes of /nitrogen oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 265 mg/kg from table
- Inhalation: LC50 Rat inhalation 252 ppm/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group B2 Probable Human Carcinogen
Reproductive toxicity
No information is available on the reproductive or developmental effects of 1,1-dimethylhydrazine in humans. Sperm abnormalities and decreased sperm counts were observed in animals injected with 1,1-dimethylhydrazine. Birth defects were not observed in the offspring of animals exposed intraperitoneally to 1,1-dimethylhydrazine.
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. Inhalation of the vapour may cause lung oedema. See Notes. The substance may cause effects on the central nervous system and liver.
STOT-repeated exposure
The substance may have effects on the blood. This may result in anaemia. This substance is possibly carcinogenic to humans.
Aspiration hazard
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Pimephales promelas (Fathead minnow, 30 day old) 7.85 mg/L/96 hr (confidence limit: 7.16-8.62 mg/L); flow-through, 24.5 deg C, 7.4 mg/L dissolved O2, hardness 46.4 mg CaCO3/L, alkalinity 42.8 mg CaCO3/L
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
Contaminated wastewater from the NASA Kennedy Space station was studied in batch cultures and trickle bed reactors to monitor the degradation rates of hydrazine containing rocket fuels(1,2). The half-life of structurally similar methylhydrazine in batch cultures (Rhodococcus B30 or Achromobacter sp.) and trickle bed reactors was about 2.5 and 12 days, respectively(1). Biodegradation may be a significant removal process at low concentrations in soils or ambient waters, but at higher concentrations hydrazines are toxic to microorganisms(2). Concentrations of hydrazine and 1,1-dimethylhydrazine that reduced bacterial metabolism by 50% ranged from 14.6 to 145 mg/L and from 19.2 to 9,060 mg/L, respectively(3).
Bioaccumulative potential
An estimated BCF value of 3 was calculated for 1,1-dimethylhydrazine(SRC), using an estimated log Kow of -1.19(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Of the initial amount of 1,1-dimethylhydrazine in cleaned sand (100% sand), Vandenburg Air Force Base (VAFB) soil (99.1% sand, 0.4% clay, pH 6.1), organic soil (96.1% sand, 1% clay, 1% carbon, pH 6.4), and clay (69.3% sand, 27.95% clay, pH 3.7), 5%, 20%, 15%, and 30% was adsorbed, respectively. Passage of 2 liters of distilled, deionized water at 5 ml/min through columns containing sand, VAFB soil, organic soil and clay (10% clay soil plus 90% pure sand) in equilibrium with 10 ml of a 0.1 v/v solution of 1,1-dimethylhydrazine resulted in 99.9%, 42.5%, 21.9%, and 7.2% recovery of this compound, respectively(1). As the hydrazines are all very basic chemicals, adsorption to acidic, clay soils is expected(1).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1163 (For reference only, please check.)
IMDG: UN1163 (For reference only, please check.)
IATA: UN1163 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: DIMETHYLHYDRAZINE, UNSYMMETRICAL (For reference only, please check.)
IMDG: DIMETHYLHYDRAZINE, UNSYMMETRICAL (For reference only, please check.)
IATA: DIMETHYLHYDRAZINE, UNSYMMETRICAL (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Depending on the degree of exposure, periodic medical examination is suggested.The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.The odour warning when the exposure limit value is exceeded is insufficient.Do NOT take working clothes home.Rinse contaminated clothing with plenty of water because of fire hazard.