OSI-420
| Price | USD1.00 |
| Packge | 1g |
- Min. Order:1g
- Supply Ability:1ton
- Time:2020-01-13
Product Details
- Product NameOSI-420
- CAS No.183320-51-6
- EINECS No.200-258-5
- MFC21H22ClN3O4
- MW415.87
- AppearancePowderWhite to off-white
- storage temp. Store at -20°C
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Common Name
Density
N/A
Boiling Point
N/A
Molecular Formula
C21H22ClN3O4
Melting Point
N/A
MSDS
N/A
Flash Point
N/A
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Use of OSI-420
Desmethyl Erlotinib (OSI-420) is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor.
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Name
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol,hydrochloride
Synonym
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Description
Desmethyl Erlotinib (OSI-420) is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor.
Related Catalog
In Vivo
Desmethyl Erlotinib exposure (AUC) in plasma is 30% (range 12-59%) of erlotinib, and Desmethyl Erlotinib clearance is more than 5-fold higher than erlotinib. The CSF penetration of erlotinib and Desmethyl Erlotinib is <5% relative to total plasma concentration[1].
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Molecular Formula
C21H22ClN3O4
Molecular Weight
415.870
Exact Mass
415.129883
PSA
85.73000
LogP
3.62600
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OSI-420
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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