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Homecompany CYCLOSPORIN D
	CYCLOSPORIN D
	CYCLOSPORIN D

CYCLOSPORIN D

Price USD1.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:1ton
  • Time:2020-01-03

Product Details

  • Product Name CYCLOSPORIN D
  • CAS No. 63775-96-2
  • EINECS No.200-258-5
  • MFC63H113N11O12
  • MW1216.64
  • AppearanceColorless to off-white crystalline solid.White to Off-White
  • Melting point 148-1510C
  • storage temp. -20°C Freezer
  • Boiling point 1294.7±65.0 °C(Predicted)
  • density 1.015±0.06 g/cm3(Predicted)
CYCLOSPORIN D Basic information
Product Name:
Synonyms:
Cyclosporine EP Impurity D;CYCLOSPORIN D;Val2-cyclosporine;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];7-L-Valinecyclosporin A;Cyclosporine IMpurity-D
CAS:
MF:
C63H111N11O12
MW:
1214.62
EINECS:
806-434-4
Mol File:
CYCLOSPORIN D Structure
 
CYCLOSPORIN D Chemical Properties
Melting point 
148-1510C
alpha 
D20 -245° (c = 0.52 in CHCl3); D20 -211° (c = 0.51 in methanol)
Boiling point 
1294.7±65.0 °C(Predicted)
density 
1.015±0.06 g/cm3(Predicted)
Fp 
9 °C
storage temp. 
-20°C Freezer
pka
13.22±0.70(Predicted)
form 
Colorless to off-white crystalline solid.
InChIKey
YJDYDFNKCBANTM-QCWCSKBGSA-N
 
Safety Information
Hazard Codes 
Safety Statements 
RIDADR 
UN 1648 3 / PGII
WGK Germany 
2
HS Code 
29419090
MSDS Information
 
 
CYCLOSPORIN D Usage And Synthesis
Chemical Properties
Colorless Crystalline Solid
Uses
A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Uses
Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumour-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.
Uses
Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;
  • Since:2014-12-17
  • Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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