Atenolol - ChemicalBook India

Price	USD10.00
Packge	1KG

Product Details

Product NameAtenolol
CAS No.29122-68-7
EINECS No.249-451-7
MFC14H22N2O3
MW266.34
InChIKeyMETKIMKYRPQLGS-UHFFFAOYSA-N
Appearancepowderwhite to off-white
Melting point 154°C
storage temp. 2-8°C
Boiling point 409.54°C (rough estimate)
density 1.0807 (rough estimate)
Water Solubility 13.5mg/L(25 ºC)

Atenolol ,also known as atenolol, Aten Yue Er, tamoxifen, downhill Ling blood pressure, Tenormin, blood pressure Ling, is a long-acting cardioselective β1-adrenergic blockers, without intrinsic sympathomimetic activity or membrane stability.The atenolol,s retardation for β1 adrenaline receptors is similar with metoprolol, propranolol and nadolol , which is 1/6 times for pindolol and timolol. But, it does not inhibit the effect of the isoproterenol bronchodilator.When administered in small doses, it does not like non-selective β-adrenergic blockers as aggravated hypoglycemia induced hypertensive crisis, peripheral circulatory impairment or patients with obstructive airways disease worsening airway function and so on. However, When administered in large doses, atenolol also can decrease asthma or chronic obstructive pulmonary disease, airway function. Atenolol, as a long-term treatment of hypertension, also were reported for affecting airway function. Thus, despite atenolol heart selection, chronic obstructive pulmonary disease patients can only use small doses, but also should be given a sufficient amount of β1-adrenergic receptor agonists.
Oral F is 46%~60%, Tmax about 2~4 h, Mainly unchanged since the urine excretion, T1/2 of 6~7 h. Hemodialysis can clear the goods. Rapidly absorbed from the gastrointestinal tract, but not exclusively.The rest of the body is excreted in the stool. Food can reduce the F, fasting and after meals AUC decreased by 20%. Distribution of the central nervous system is relatively few. The ratio of brain tissue to blood concentration was 0.1:1. Easy to achieve in the placenta and the maternal plasma concentrations of same. PPB is less than 5%, Vd is 50~75 L. Atenolol is not metabolized by the liver, most of the drug is excreted from the body in urine, renal insufficiency in patients with T1/2 was significantly prolonged. Patients with renal failure range of T1/2 was 10~28 h, or even up to 100 h. Results at 24 h after, the discharge from the urine of the drug can be reduced by 29%. The T1/2 of patients with hyperthyroidism was significantly shortened, 4.2h.

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3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
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Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.

FAQ

1. What's your payment terms?
T/T or L/C, D/P,D/A,WU,MG.
2. What's your delivery time?
Usually we will arrange the shipment in 7 -15 days.
3. How about the packing?
Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.
4. When can I Get Reply?
Our Area sales manager will contact you as soon as possible in 24 hours one working day!
5. How about the validity of the products?
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6. What documents you provide?
Usually, we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
7. What certificate you can provide?
According to different kinds of product, we have various certificates like:Halal,Kosher,Haccp,GMP,Iso,Organic Certificate
8. What is loading port?
Usually is Shanghai,Qingdao or Tianjin.

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Company Profile Introduction

Shijiazhuang Erche Biotechnology Co., Ltd is a professional pharmaceutical intermediates company, located in Shijiazhuang City,Hebei Province,China.We are engaged in the manufacturer and supply of pharmaceutical intermediates,organic intermediate, BMK, PMK, API, NMN, nootropics, nutrition ingredients, cosmetic ingredients, sex enhancer, plant extracts,etc.In the past years, our products have spread over more than 50 countries in the world.Most of the products produced and sold are exported abroad,and it is well-received in all around the world for its excellent quality.Our goal is to survive by quality and develop by credit. In the past two years,our products have spread over more than 30 countries in the world, the U.S.A, the Netherlands, Poland, Canada, England, Italy, India, Columbia and so on. We work with friends all over the world to develop the best quality products, the most reasonable prices, safe and effective transportation. Product can be ordered from milligrams to tons to meet the purchase of new and old customers.

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2025-09-23