(3,4-Dihydroxybenzylidene)-malononitrile
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:20kg
- Time:2019-09-06
Product Details
- Product Name(3,4-Dihydroxybenzylidene)-malononitrile
- CAS No.118409-57-7
- MFC10H6N2O2
- MW186.17
- AppearanceYellow solidYellow
- storage temp. 2-8°C
- Melting point 225°C
- Boiling point 421.1±45.0 °C(Predicted)
- density 1.428±0.06 g/cm3(Predicted)
Abby024
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AG 18 Basic information
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Product Name:
Synonyms:
AG 18 - CAS 118409-57-7 - Calbiochem;TYRPHOSTIN A23 99+%;(3,4-Dihydroxybenzylidene)-malononitrile, RG-50810;AG 18 (Tyrphostin A23);2-(3,4-Dihydroxyphenyl)ethene-1,1-dicarbonitrile;4,5-Dihydroxybenzylidenemalononitrile;(3,4-Dihydroxyphenyl)methylene propanedinitrile;Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)-
CAS:
MF:
C10H6N2O2
MW:
186.17
EINECS:
Product Categories:
Mol File:
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AG 18 Chemical Properties
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Melting point
225°C
storage temp.
2-8°C
solubility
Soluble in DMSO, ethanol, or DMF
form
Yellow solid
λmax
464nm(DMSO)(lit.)
Stability:
Store in refrigerator
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Safety Information
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WGK Germany
3
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English
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AG 18 Usage And Synthesis
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Chemical Properties
Yellow Powder
Uses
A specific inhibitor for the epidermal growth factor receptor. Also inhibits EGF-dependent cell proliferation (IC50=35uM)
Uses
AG 18 inhibits EGFR with IC50 of 35 μM.
Biological Activity
Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC 50 values are 35 and 25 μ M respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling.
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AG 18 Preparation Products And Raw materials
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Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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