Butoconazole
| Price | USD1.00 | USD2.00 |
| Packge | 1KG | 1KG |
- Min. Order:1KG
- Supply Ability:200kg
- Time:2019-09-02
Product Details
- Product NameButoconazole
- CAS No.64872-76-0
- MFC19H17Cl3N2S
- MW411.78
- AppearanceSolidWhite to off-white
- Melting point 68-70.5°
- density 1.32±0.1 g/cm3(Predicted)
- Boiling point 566.9±50.0 °C(Predicted)
- storage temp. Store at -20°C
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Product Name:
Synonyms:
BUTOCONAZOLE;Butooonazole;BUTONAZOLE;1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanyl-butyl]imidazole;(±)-1-[4-(4-Chlorophenyl)-2-[(2，6-dichlorophenyl)thio]butyl]-1H-imidazole;1-[2-[(2,6-Dichlorophenyl)thio]-4-(4-chlorophenyl)butyl]-1H-imidazole
CAS:
MF:
C19H17Cl3N2S
MW:
411.78
EINECS:
Product Categories:
Mol File:
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Butoconazole Chemical Properties
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Melting point
68-70.5°
CAS DataBase Reference
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Safety Information
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Butoconazole Usage And Synthesis
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Uses
antineoplastic, pyrimidine antimetabolite
Definition
ChEBI: A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to the nitrogen is substituted by a 4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl group. An antifungal agent, it is used as its nitrate sa t in gynaecology for treatment of vulvovaginal infections caused by Candida species, particularly Candida albicans.
Brand name
Femstat (Roche);Femstat 3 (Bayer); Gynazole-1 (KV Pharmaceutical).
Enzyme inhibitor
This fungicide (FW = 411.78 g/mol; CAS 64872-77-1), also known as Femstat?, Femstat-3?, Gynazole-1?, and systematically as 1-[4- (4- chlorophenyl) -2-[ (2,6-dichlorophenyl) -sulfanyl]butyl]-1H-imidazole (* = chiral center), is believed to inhibit steroid synthesis, targeting the conversion of lanosterol to ergosterol and modifying membrane composition/function. At 80 μM, butoconazole was strictly fungistatic against early stationary-phase Candida albicans cells. During early log- phase growth, butoconazole were highly lethal at 20 μM. In 1995, butoconazole was approved for treatment of vaginal yeast infections.
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Butoconazole Preparation Products And Raw materials
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Raw materials
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Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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