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Carbamazepine
Carbamazepine

Carbamazepine

Price USD1.00
Packge 1kg
  • Min. Order:1kg
  • Supply Ability:High quality Factory
  • Time:2020-06-02

Product Details

  • Product NameCarbamazepine
  • CAS No.298-46-4
  • EINECS No.206-062-7
  • MFC15H12N2O
  • MW236.27
  • InChIKeyFFGPTBGBLSHEPO-UHFFFAOYSA-N
  • AppearanceCrystalsAlmost white
  • Water Solubility pract. insoluble
  • storage temp. 2-8°C
  • Melting point 191-192 °C (lit.)
  • Boiling point 378.73°C (rough estimate)
  • density 1.1099 (rough estimate)
Product Name: Carbamazepine
Synonyms: 5H-Dibenz[b,f]azepine-5-carboxamine;5H-Dibenzo[b,f]azepine-5-carboxamide;Biston;Calepsin;Carbamazepen;Carbamezepine;Carbazepine;Carbelan
CAS: 298-46-4
MF: C15H12N2O
MW: 236.27
EINECS: 206-062-7
Product Categories: Pharmaceutical;Acids and Derivatives;Heterocycles;Active Pharmaceutical Ingredients;APIs;Pharmaceutical raw material;TEGRETOL;Pharmaceutical Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Isotope Labelled Compounds
Mol File: 298-46-4.mol
Carbamazepine Structure
 
Carbamazepine Chemical Properties
Melting point  189-192 °C
Boiling point  378.73°C (rough estimate)
density  1.1099 (rough estimate)
refractive index  1.5906 (estimate)
Fp  9℃
storage temp.  2-8°C
solubility  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL
form  Crystals
color  Almost white
Water Solubility  pract. insoluble
Merck  14,1781
CAS DataBase Reference 298-46-4(CAS DataBase Reference)
NIST Chemistry Reference Carbamazepine(298-46-4)
 
Safety Information
Hazard Codes  Xn,T,F
Risk Statements  42/43-22-20/21/22-39/23/24/25-23/24/25-11
Safety Statements  37-24-22-36/37/39-36-45-36/37-16
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  HN8225000
HS Code  29339900
Hazardous Substances Data 298-46-4(Hazardous Substances Data)
Toxicity LD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet)
MSDS Information
Provider Language
Carbamazepine English
ACROS English
 
Carbamazepine Usage And Synthesis
Overview Carbamazepine (CBZ) is an irninostilbene derivative, structurally similar to the tricyclic antidepressants. Chemically. CBZ is a neutral, liposoluble compound that can easily pass the bloodlbrain barrier and other membranes in the body. Developed and marketed for the treatment of epileptic seizures and trigeminal neuralgia, CBZ has been utilized more and more frequently in the last decade to treat psychiatric disorders.
Carbamazepine was first evaluated as a potential treatment in manic depressive psychosis by Takezaki and Hanaoka (1971)[1], and Okuma et al. (1973)[2]. In 1979, Okuma et al.[3] performed the first double-blind trial of carbamazepine in comparison with the antipsychotic chlorpromazine in mania and found that 70% and 60% of patients improved respectively. A further placebo-controlled double-blind study replicated the antimanic properties of carbamazepine under controlled circumstances (Ballenger and Post, 1980). There have since been many studies demonstrating the efficacy of carbamazepine in treating the acute manic and depressive symptoms of bipolar disorder, as well as in prophylaxis[4, 5].
Carbamazepine Basic information
Overview Indication Dosage and administration Plasma levels monitoring Cautions Pharmacodynamics Interactions Special populations Mode of action Psychiatric use Adverse reactions and precaution References

 

 

 

 

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.

 

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

 

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis. 

 

Think Chemistry,Think CHemWill

 

 

 

 

 

Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China


Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA

 

 

---any inquiries will be replied within 12 hours.

---golden manufactory under iso/gmp with large stock.

---dedication to quality,we have strict quality control system. 

---oem/odm available.

---sample is available for your evaluation & formulation development.

 
 

 

 

PLS contact

Ms Ella Lee  -   Deputy Sales Manager  

 
Phone: +86 -21-51086038
 

Email: chemwill_asia@126.com;ch

Company Profile Introduction

Over 30 years experience in the chemical industry, Chemwill Asia co.,Ltd is one of the leading manufacturer of Organic compounds in CHINA. We own GMP licence as well as ISO certificate paper. CHemwill employs over 165 peoples including professional technical experts and professional-trained workers. The sales volume of our company in 2018 is over 8.5 million dollars.
Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 
 
Our advantageous business including: 

- Intermediate using for Pharmaceuticals

- Fluorine, boronic acids, unnatural amino acids, cross linkers,chiral building blocks

- Intermediate using for advanced performance materials
- Monomer & polymers, high performance, photosensitive and specialty chemicals 
- Electro chemical materials(Lithium Battery, Photoresist, semiconductor, IT-related chemicals) 
 
* Custom synthesis from the laboratory scale to commercial production. 
* Contract research, custom manufacturing and contract-manufacture 
 
Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.

Think Chemistry,Think CHemWill

Recommended supplier

Chemwill Asia Co.,Ltd.

Shanghai CHINA
  • Since:2004-09-01
  • Address: BLDG 9,No.235 Sanlin road,Pudong new district,Shanghai,China
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