STAUROSPORINE
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:1T
- Time:2019-07-06
Product Details
- Product NameSTAUROSPORINE
- CAS No.62996-74-1
- EINECS No.613-127-7
- MFC28H26N4O3
- MW466.54
- AppearanceWhite to pale yellow solidOff white to pale yellow
- storage temp. 2-8°C
- Melting point 270°C
- Water Solubility Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.
- Boiling point 677.5±55.0 °C(Predicted)
- density 1.56±0.1 g/cm3(Predicted)
CR363
| Product Name: | STAUROSPORINE |
| Synonyms: | STSP;ANTIBIOTIC M 193;ANTIBIOTIC AM-2282;[9S-(9A,10B,11B,13A)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-1M]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE;2,3,10,11,12,13-HEXAHYDRO-10R-METHOXY-9S-METHYL-11R-METHYLAMINO-9S,13R-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1 ONE;STAUROSPORINE FROM STREPTOMYCES SP.;STAUROSPORINE READY-MADE SOLUTION;STAUROSPORINE FROM STREPTOMYCES SP., PGE WITH 250 UG |
| CAS: | 62996-74-1 |
| MF: | C28H26N4O3 |
| MW: | 466.53 |
| EINECS: | |
| Product Categories: | All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Protein Kinase;Signalling;Inhibitor;antibiotic;API |
| Mol File: | 62996-74-1.mol |
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| STAUROSPORINE Chemical Properties |
| Melting point | 270°C |
| alpha | D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol) |
| RTECS | KD5084000 |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| Water Solubility | Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water. |
| InChIKey | HKSZLNNOFSGOKW-WIFUGMKFSA-N |
| Safety Information |
| Hazard Codes | Xn,T,Xi |
| Risk Statements | 40-45-36/37/38-46 |
| Safety Statements | 36/37-53-36-26-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | 2 |
| F | 8-10 |
| HazardClass | 3 |
| HS Code | 29419090 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| STAUROSPORINE Usage And Synthesis |
| Chemical Properties | Light Yellow Solid |
| Uses | Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumour active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta. |
| Uses | Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumor active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta. |
| Uses | A protein Kinase C inhibitor that induces apoptosis in many cell types |
| Biological Activity | Broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC 50 = 3 nM), protein kinase A (IC 50 = 7 nM), p 60v-src tyrosine protein kinase (IC 50 = 6 nM) and CaM kinase II (IC 50 = 20 nM). Also available as part of the Mixed Kinase Inhibitor Tocriset™ . |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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