Fluoxetine hydrochloride
| Price | USD5.50 |
| Packge | 25Kg/Drum |
- Min. Order:1ASSAYS
- Supply Ability:200tons per month
- Time:2021-01-06
Product Details
- Product NameFluoxetine hydrochloride
- CAS No.56296-78-7
- EINECS No.260-101-2
- MFC17H19ClF3NO
- MW345.79
- Appearancesolidwhite
- Melting point 158-159°C
- storage temp. 2-8°C
- Water Solubility Soluble in dimethylsulfoxide and water.
| Product Name: | fluoxetine hydrochloride |
| Synonyms: | Fluoxetine HCL; Fluoxetinhydrochloride; Fluoxetin HCL; N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride (1:1); 6,11-dihydroxy-3,3-dimethyl-5-(3-methylbut-2-en-1-yl)-3,12-dihydro-7H-pyrano[2,3-c]acridin-7-one HCL |
| CAS RN.: | 56296-78-7 |
| EINECS: | 260-101-2 |
| Molecular Weight: | 345.79 |
| Molecular Formula: | C17H18F3NO·HCl |
| Density: | 1.254g/cm3 |
| Boiling Point(℃): | 569.2°C at 760 mmHg |
| Flash Point(℃): | 298°C |
| refractive_index: | 1.63 |
Introduction
Fluoxetine was shown to be effective for depression in six-week-long double-blind controlled trials, where it also alleviated anxiety and improved sleep. Fluoxetine was better than placebo for the prevention of depression recurrence when the patients, who originally responded to fluoxetine, were treated for a further 38 weeks. Efficacy of fluoxetine for geriatric, as well as pediatric, depression was also demonstrated in placebo-controlled trials.
Research suggests that a significant part of the resistance to the SSRIs paroxetine (Paxil) and citalopram(Celexa) can be explained by the genetic variation of Pgp transporter. Paroxetine and citalopram, which are Pgp substrates, are actively transported from the brain by this protein. Fluoxetine is not a substrate of Pgp, and thus a switch from paroxetine or citalopram to fluoxetine may be beneficial to the nonresponders.
Function
Fluoxetine is frequently used to treat major depression, obsessive compulsive disorder, bulimia nervosa,panic disorder, body dysmorphic disorder, premenstrual dysphoric disorder, and trichotillomania. Caution should be taken when using any SSRI for bipolar disorder as this can increase the likelihood of mania; however, fluoxetine can be used with an antipsychotic (such as quetiapine) for bipolar. It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.
Company Profile Introduction
Qingdao Trust Agri Chemical Co.,Ltd is located in Qingdao, Shandong Province. Our company is a professional chemicals exporter, products included: Agro chemicals, Intermediates, Inorgannic salt and other chemicals.
- Since:2016-04-04
- Address: No.689 Qingwei Road, Chengyang Subdistrict, Chengyang District, Qingdao, Shandong