XantPhos Pd G3

1445085-97-1

XantPhos Pd G3

Synonym: [(4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate

CAS Number 1445085-97-1

Formula: C52H45NO4P2PdS

Formula Weight: 948.35 g/mol

Appearance (Color) Light Green to Dark Green to Dark Yellow

assay  95%

mp  164-167 °C (decomposition)

Caution : air sensitive 

shelf life :12 month 

Supplier: LPBchem-Benjamin

Related Categories

Buchwald 3rd Generation Palladacycles, Buchwald Ligands and Complexes, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling,

Homogeneous Pd Catalysts, Palladium Catalysts

General description

XantPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. XantPhos Pd G3 is an excellent reagent for palladium catalyzed cross-coupling reactions. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Application

XantPhos Pd G3 may be used in the following processes:

- Negishi cross-coupling reaction during the synthesis of palmerolides.

-Aminocarbonylation of heteroaryl bromides with carbon monoxide (CO) in the presence of triethylamine.

-Coupling between polyglycosyl thiols and aglycon halides by C-S bond formation