Product Details
- Product NameLY 171883
- CAS No.88107-10-2
- MFC16H22N4O3
- MW318.37
- AppearanceWhite solid.White
- storage temp. Store at +4°C
- Melting point 117-119℃
- Boiling point 553.0±60.0 °C(Predicted)
- density 1.220±0.06 g/cm3(Predicted)
Email: amy@coreychem.com
Career Henan Chemical Co
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| LY 171883 Basic information |
| Product Name: |
LY 171883 |
| Synonyms: |
TOMELUKAST;LY-171,833;LY 171883;5-[4-4-ACETYL-3-HYDROXY-2-PROPYLPHENOXYBUTYL]-1H-TETRAZOLE;5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE;1-[2-HYDROXY-3-PROPYL-4-[4-(1H-TETRAZOL-5-YL)BUTOXY]PHENYL]ETHANONE;1-(2-hydroxy-3-propyl-4-(4-(1h-tetrazol-5-yl)butoxy)phenyl)-ethanon;2’-hydroxy-3’-propyl-4-(4-(1h-tetrazol-5-yl)butoxy)-acetophenon |
| CAS: |
88107-10-2 |
| MF: |
C16H22N4O3 |
| MW: |
318.37 |
| EINECS: |
|
| Product Categories: |
Prostanoid receptor and related |
| Mol File: |
88107-10-2.mol |
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| |
| LY 171883 Chemical Properties |
| Melting point |
117-119℃ |
| Boiling point |
553.0±60.0 °C(Predicted) |
| density |
1.220±0.06 g/cm3(Predicted) |
| storage temp. |
Store at +4°C |
| form |
White solid. |
| pka |
5.02±0.10(Predicted) |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| Safety Statements |
36 |
| WGK Germany |
3 |
| RTECS |
KM5780800 |
| |
| LY 171883 Usage And Synthesis |
| Definition |
ChEBI: A member of the class of acetophenones that is 1-phenylethanone substituted at position 2 by a hydroxy group, a propyl group at position 3 and a 4-(1H-tetrazol-5-yl)butoxy group at position 4. A leukotriene antagonist, it exhibits anti asthmatic activity. |
| Biological Activity |
Selective, orally active leukotriene D 4 (LTD 4 ) antagonist; inhibits binding of [ 3 H]-LTD 4 to guinea pig lung membranes (K i = 0.63 μ M).? Acts as an agonist at peroxisome proliferator-activated receptors (PPARs). |
Company Profile
Introduction
Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).
