Product Details
- Product NameFOSTRIECIN SODIUM SALT
- CAS No.87860-39-7
- MFC19H28NaO9P
- MW454.39
- AppearanceColorless solid
- storage temp. -20°C
- Water Solubility Soluble to 100 mM in water
Heidi 483
| FOSTRIECIN SODIUM SALT Basic information |
| |
| FOSTRIECIN SODIUM SALT Chemical Properties |
| storage temp. |
−20°C |
| form |
Colorless solid |
| WGK Germany |
3 |
| RTECS |
UQ0600000 |
| |
| FOSTRIECIN SODIUM SALT Usage And Synthesis |
| Uses |
Antineoplastic. |
| Biological Activity |
Originally identified as an antitumor antibiotic from Streptomyces pulveraceous . Displays potent inhibition of protein phosphatase types 2A (PP2A) and 4 (PP4) with IC 50 values of 1.5 nM and 3 nM respectively. Also exhibits weaker inhibition of topoisomerase II (IC 50 = 40 μ M) and protein phosphatase type 1 (PP1) (IC 50 = 131 μ M) with no apparent inhibition of protein phosphatase type 2B (PP2B). Active in vivo . |
Company Profile
Introduction
Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).
