Product Details
- Product NameMidecamycin Acetate
- CAS No.55881-07-7
- EINECS No.2598796
- MFC45H71NO17
- MW898.046
- Melting point ~220° (with coloration)
- Boiling point 878.7±65.0 °C(Predicted)
- density 1.20±0.1 g/cm3(Predicted)
| Midecamycin Acetate Basic information |
| Product Name: |
Midecamycin Acetate |
| Synonyms: |
Midecamycin Acetate;Leucomycin V, 3B,9-diacetate 3,4B-dipropanoate;3'',9-Diacetylmydecamycin;9,3''-Di-O-acetylmidecamycin;Acecamycin;Leucomycin V, 3B,9-diacetate 3,4B-dipropanoate (9CI);Miocamycin;Miokamycin |
| CAS: |
55881-07-7 |
| MF: |
C45H71NO17 |
| MW: |
898.046 |
| EINECS: |
259-879-6 |
| Product Categories: |
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| Mol File: |
55881-07-7.mol |
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| Midecamycin Acetate Chemical Properties |
| Melting point |
~220° (with coloration) |
| alpha |
D25 -53° (c = 1.0 in chloroform); D20 -74° (c = 1 in methanol) |
| Boiling point |
878.7±65.0 °C(Predicted) |
| density |
1.20±0.1 g/cm3(Predicted) |
| pka |
13.06±0.70(Predicted) |
| |
| Midecamycin Acetate Usage And Synthesis |
| Description |
Miokamycin (midecamycin acetate) is a macrolide antibiotic useful in the treatment of respiratory tract, dermatological and surgical infections due to grampositive bacteria and mycoplasmas. |
| Originator |
Meiji Seika (Japan) |
| Brand name |
MIOCAMYCIN |
| Pharmaceutical Applications |
A semisynthetic diacetyl derivative of midecamycin A1. It is generally less active than erythromycin and some strains of H. influenzae and E. faecalis are resistant. It is rapidly and extensively metabolized, though some metabolites retain antibacterial activity.
Absorption of the dry formulation is unaffected by food, whereas that of the oral suspension is delayed. In various studies the peak plasma concentration was 1.65, 1.31–3 and 1.3–2.7 mg/L after doses of 400, 600 and 800 mg, respectively.
It is said to exhibit less toxicity than earlier macrolides. Attention has been paid to its interaction with theophylline, which resembles that of other macrolides. It is of limited availability. |
Company Profile
Introduction
Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).
