Tamoxifen base

Price	Get Latest Price
Packge	1Kg

Min. Order:1g
Supply Ability:5000kg
Time:2021-12-23

Product Details

Product NameTamoxifen
CAS No.10540-29-1
EINECS No.234-118-0
MFC26H29NO
MW371.51
AppearanceneatCrystals from pet ether
Melting point 97-98 °C(lit.)
storage temp. 2-8°C
Water Solubility Insoluble in water. Soluble in methanol, ethanol, propanol or propylene glycol.Soluble in dimethyl sulfoxide, dichloromethane and ethanol. Insoluble in water.
Boiling point 501.18°C (rough estimate)
density 1.0630 (rough estimate)

Product Name: Tamoxifen

CAS: 10540-29-1

MF: C26H29NO

MW: 371.51

EINECS: 234-118-0

Melting point 97-98 °C(lit.)

Boiling point 501.18°C (rough estimate)

density 1.0630 (rough estimate)

refractive index 1.6000 (estimate)

storage temp. 2-8°C

solubility H2O: insoluble <0.1% at 20°C

pka pKa 8.71(H2O t = 25 I = 0.025) (Uncertain)

Uses A nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines

Uses Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Company Profile Introduction

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD is located in Jiangxia District, Wuhan City, Hubei Province. Main pharmaceutical intermediates, raw materials, food additives, antibiotics raw materials, etc. Wuhan dongkangyuan Technology Co., Ltd. is located in Wuhan, the thoroughfare of nine provinces. It is a high-tech industrial company specializing in the R & D and sales of chemical raw materials in Central China. The company has its own R & D base, equipped with advanced production equipment and high-efficiency precision testing instruments, with a complete, scientific and quality management system. And constantly committed to technological innovation, product innovation and management innovation, with high-tech and excellent innovation quality service has won the trust of University organs, scientific research institutions, pharmaceutical manufacturers, quality inspection departments, environmental protection enterprises, chemical production, agricultural production, food related industries and other industries. In order to ensure that our products in the same industry with super competitiveness. The company has independent import and export operation rights and excellent sales team.

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Hubei CHINA

Since:2013-04-05
Address: Yuanfen Road community, Wuchang District, Wuhan City

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