Zolbetuximab
- CAS NO.：1496553-00-4
- Molecular Weight: 0
- Update Date: 2025-12-16 21:30:20
What is Zolbetuximab?
The Uses of Zolbetuximab
Zolbetuximab (development code IMAB362) is an experimental monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors.
Mechanism of action
Zolbetuximab is the first drug developed against the target of Claudin18.2. It is a chimeric IgG1 monoclonal antibody that specifically binds to Claudin18.2 on the surface of tumor cells, thereby triggering antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), apoptosis and inhibition of cell proliferation.
Safety information for Zolbetuximab
New Products
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