ZM 449829
Synonym(s):(2-Naphthylvinyl Ketone), ZM 449829;JAK3 Inhibitor V - CAS 932258 - Calbiochem
- CAS NO.：4452-06-6
- Empirical Formula: C13H10O
- Molecular Weight: 182.22
- MDL number: MFCD04974535
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-10 09:00:29
What is ZM 449829?
The Uses of ZM 449829
ZM 449829, is a potent, selective inhibitor of JAK3 (Janus tyrosine kinase 3) which binds competitively to the JAK3 ATP site. Also inhibits STAT-5 phosphorylation and T-cell proliferation.
What are the applications of Application
JAK3 Inhibitor V is a selective JAK3 inhibitor
Definition
ChEBI: 1-(2-naphthalenyl)-2-propen-1-one is a member of naphthalenes.
Properties of ZM 449829
| Boiling point: | 319.3±15.0 °C(Predicted) |
| Density | 1.093±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | White waxy solid |
Safety information for ZM 449829
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for ZM 449829
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