ZIZYPHINE

Description

A peptide alkaloid present in Zizyphus aenoplia Mill., this base forms colourless crystals from EtOH and is strongly laevorotatory with [α]^{24/sup>_D - 464.7° (c 1.0, CHCI3 ). The ultraviolet spectrum in EtOH has absorption maxima at 206, 267 and 319 mμ, and that in dioxan has maxima at 243, 273 and 321 mμ. The alkaloid yields crystalline salts including the hydrochloride, m.p. 184-5°C; perchlorate, m.p. 268-9°C (dec.) and the oxalate, m.p. 139.5-140.5°C. It is probably identical with the Zizyphine A, having the structure given above, recently obtained from the same source by Tschesche and his colleagues.}

References

Menard et ai., Helv. Chirn. Acta, 46, 1801 (1963) Tschesche, Kaussmann, Eckhardt., Tetrahedron Lett., 2577 (1973)