Z-D-Arg-Gly-Arg-PNA 2 HCl
- CAS NO.：113711-77-6
- Empirical Formula: C28H40ClN11O7
- Molecular Weight: 678.15
- MDL number: MFCD03093407
- Update Date: 2026-09-12 18:54:55
What is Z-D-Arg-Gly-Arg-PNA 2 HCl?
Description
Z-D-Arg-Gly-Arg-pNA is a colorimetric substrate for Factor Xa.1,2 Factor Xa preferentially binds to and cleaves the Arg-Gly-Arg (RGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.
The Uses of Z-D-Arg-Gly-Arg-PNA 2 HCl
Z-D-Arg-Gly-Arg-pNA Dihydrochloride is a reagent used in the preparation and testing of tripeptides and intermediates (arginine-containing) as reagent for the determination of serine protease.
References
1. Gustavsson, S.I., and Arielly, S. New Peptide Derivatives ,(1989).
2. Joo, H.-S., Park, G.-C., Kim, K.-M., et al. Novel alkaline protease from the polychaeta, Periserrula leucophryna: Purification and characterization Proc. Biochem. 36(8-9),893-900(2001).
Properties of Z-D-Arg-Gly-Arg-PNA 2 HCl
| storage temp. | Store at -20°C |
| solubility | DMF: 14 mg/ml; DMSO: 14 mg/ml; Ethanol: partially soluble; PBS (pH 7.2): 0.5 mg/ml |
| form | A solid |
| Stability: | Hygroscopic |
Safety information for Z-D-Arg-Gly-Arg-PNA 2 HCl
Computed Descriptors for Z-D-Arg-Gly-Arg-PNA 2 HCl
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