Y-29794 tosylate
- CAS NO.：143984-17-2
- Empirical Formula: C30H42N2O4S3
- Molecular Weight: 590.86
- MDL number: MFCD30533391
- Update Date: 2026-04-14 09:55:04
What is Y-29794 tosylate?
Description
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. Y-29794 selectively and competitively inhibited rat brain PPCE (Ki = 0.95 nM) in a reversible manner. Ex vivo study demonstrated that Y-29794 could penetrate into brain to exhibit dose-dependent and long-lasting inhibition. Furthermore, Y-29794 could potentiate the effect of TRH on the release of ACh in the rat hippocampus. Y-29794 prevents the progression of A beta-like deposition in the hippocampus of the SAM.
Safety information for Y-29794 tosylate
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